Potassium in PDB 6w7d: K2P2.1 (Trek-1), 10 Mm K+

The structure of K2P2.1 (Trek-1), 10 Mm K+, PDB code: 6w7d was solved by M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.95 / 3.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.306, 122.652, 126.127, 90, 90, 90
R / Rfree (%)	28.2 / 31.1

The structure of K2P2.1 (Trek-1), 10 Mm K+ also contains other interesting chemical elements:

Cadmium

(Cd)

3 atoms

The binding sites of Potassium atom in the K2P2.1 (Trek-1), 10 Mm K+ (pdb code 6w7d). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the K2P2.1 (Trek-1), 10 Mm K+, PDB code: 6w7d:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the K2P2.1 (Trek-1), 10 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of K2P2.1 (Trek-1), 10 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K407 b:156.2 occ:1.00 O A:THR142 2.8 138.2 1.0 O B:THR142 2.8 137.7 1.0 O A:ILE143 2.9 191.1 1.0 O A:THR251 3.0 135.9 1.0 O B:ILE143 3.0 172.9 1.0 O B:ILE252 3.0 183.3 1.0 O A:ILE252 3.1 151.1 1.0 O B:THR251 3.5 137.9 1.0 K A:K408 3.6 162.1 1.0 C A:ILE143 3.7 199.7 1.0 C B:ILE252 3.7 183.8 1.0 C A:ILE252 3.8 159.3 1.0 C B:ILE143 3.8 155.7 1.0 C A:THR251 4.0 140.0 1.0 C A:THR142 4.0 138.5 1.0 C B:THR142 4.0 147.7 1.0 CA A:ILE252 4.1 166.0 1.0 CA B:ILE252 4.1 179.5 1.0 CA A:ILE143 4.2 194.4 1.0 CA B:ILE143 4.2 137.0 1.0 C B:THR251 4.2 158.7 1.0 N A:ILE252 4.5 171.1 1.0 N B:ILE252 4.5 168.9 1.0 N A:ILE143 4.6 185.2 1.0 N B:ILE143 4.6 141.9 1.0 N A:GLY144 4.6 211.2 1.0 OG1 B:THR251 4.7 150.2 1.0 N B:GLY253 4.8 237.1 1.0 N A:GLY253 4.8 157.6 1.0 N B:GLY144 4.8 238.6 1.0 O B:GLY144 4.8 300.0 1.0 O A:GLY144 4.9 300.0 1.0 CA A:GLY144 5.0 246.8 1.0

Potassium binding site 2 out of 2 in the K2P2.1 (Trek-1), 10 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of K2P2.1 (Trek-1), 10 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K408 b:162.1 occ:1.00 O B:THR251 2.7 137.9 1.0 O A:THR251 2.8 135.9 1.0 O A:THR142 2.9 138.2 1.0 OG1 A:THR142 3.1 155.7 1.0 OG1 A:THR251 3.2 172.2 1.0 OG1 B:THR251 3.2 150.2 1.0 O B:THR142 3.3 137.7 1.0 CB A:THR251 3.3 161.8 1.0 OG1 B:THR142 3.4 165.1 1.0 CB A:THR142 3.6 148.3 1.0 K A:K407 3.6 156.2 1.0 CG2 B:THR251 3.6 180.1 1.0 C A:THR142 3.8 138.5 1.0 C A:THR251 3.8 140.0 1.0 CB B:THR142 3.9 148.3 1.0 C B:THR251 3.9 158.7 1.0 CB B:THR251 3.9 162.9 1.0 C B:THR142 4.2 147.7 1.0 CA A:THR251 4.2 146.7 1.0 CA A:THR142 4.3 137.0 1.0 CG2 A:THR251 4.5 177.6 1.0 CA B:THR251 4.6 160.0 1.0 N A:ILE143 4.7 185.2 1.0 CA B:THR142 4.7 146.3 1.0 O A:THR141 4.8 148.3 1.0 CG2 A:THR142 4.8 165.0 1.0 N A:ILE252 5.0 171.1 1.0 N B:ILE252 5.0 168.9 1.0

M.Lolicato, A.M.Natale, F.Abderemane-Ali, D.Crottes, S.Capponi, R.Duman, A.Wagner, J.M.Rosenberg, M.Grabe, D.L.Minor Jr.. K 2P Channel C-Type Gating Involves Asymmetric Selectivity Filter Order-Disorder Transitions. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33127683
DOI: 10.1126/SCIADV.ABC9174