Potassium in PDB 7d99: Human Potassium-Chloride Co-Transporter KCC4

The structure of Human Potassium-Chloride Co-Transporter KCC4 also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Potassium atom in the Human Potassium-Chloride Co-Transporter KCC4 (pdb code 7d99). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Potassium-Chloride Co-Transporter KCC4, PDB code: 7d99:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Human Potassium-Chloride Co-Transporter KCC4


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Potassium-Chloride Co-Transporter KCC4 within 5.0Å range: probe atom residue distance (Å) B Occ A:K1301 b:5.3 occ:1.00 O A:THR432 2.9 5.9 1.0 O A:ASN131 3.0 9.6 1.0 O A:PRO429 3.0 5.2 1.0 O A:ILE132 3.1 7.0 1.0 CL A:CL1302 3.4 14.9 1.0 OG1 A:THR432 3.5 5.9 1.0 OH A:TYR216 3.7 4.4 1.0 CA A:ILE132 3.8 7.0 1.0 C A:ILE132 3.8 7.0 1.0 C A:THR432 4.0 5.9 1.0 C A:ASN131 4.0 9.6 1.0 C A:PRO429 4.2 5.2 1.0 N A:THR432 4.3 5.9 1.0 C A:SER430 4.3 6.6 1.0 CA A:SER430 4.4 6.6 1.0 N A:ILE132 4.4 7.0 1.0 O A:SER430 4.5 6.6 1.0 CA A:THR432 4.5 5.9 1.0 CB A:THR432 4.6 5.9 1.0 N A:VAL431 4.7 4.8 1.0 N A:SER430 4.8 6.6 1.0 C A:VAL431 5.0 4.8 1.0 CB A:ILE132 5.0 7.0 1.0

Potassium binding site 2 out of 2 in the Human Potassium-Chloride Co-Transporter KCC4


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Potassium-Chloride Co-Transporter KCC4 within 5.0Å range: probe atom residue distance (Å) B Occ B:K1301 b:5.3 occ:1.00 O B:THR432 2.9 5.9 1.0 O B:ASN131 3.0 9.6 1.0 O B:PRO429 3.0 5.2 1.0 O B:ILE132 3.1 7.0 1.0 CL B:CL1302 3.4 14.9 1.0 OG1 B:THR432 3.5 5.9 1.0 OH B:TYR216 3.7 4.4 1.0 CA B:ILE132 3.8 7.0 1.0 C B:ILE132 3.8 7.0 1.0 C B:THR432 4.0 5.9 1.0 C B:ASN131 4.0 9.6 1.0 C B:PRO429 4.2 5.2 1.0 N B:THR432 4.3 5.9 1.0 C B:SER430 4.3 6.6 1.0 CA B:SER430 4.4 6.6 1.0 N B:ILE132 4.4 7.0 1.0 O B:SER430 4.5 6.6 1.0 CA B:THR432 4.5 5.9 1.0 CB B:THR432 4.6 5.9 1.0 N B:VAL431 4.7 4.8 1.0 N B:SER430 4.8 6.6 1.0 C B:VAL431 5.0 4.8 1.0 CB B:ILE132 5.0 7.0 1.0

Y.Xie, S.Chang, C.Zhao, F.Wang, S.Liu, J.Wang, E.Delpire, S.Ye, J.Guo. Structures and An Activation Mechanism of Human Potassium-Chloride Cotransporters. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33310850
DOI: 10.1126/SCIADV.ABC5883