Potassium in PDB 6npl: Cryo-Em Structure of NKCC1

The structure of Cryo-Em Structure of NKCC1 also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Potassium atom in the Cryo-Em Structure of NKCC1 (pdb code 6npl). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Cryo-Em Structure of NKCC1, PDB code: 6npl:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Cryo-Em Structure of NKCC1


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo-Em Structure of NKCC1 within 5.0Å range: probe atom residue distance (Å) B Occ A:K1201 b:17.1 occ:1.00 O A:ILE221 2.9 2.9 1.0 O A:PRO417 2.9 4.0 1.0 OH A:TYR305 2.9 5.0 1.0 O A:ASN220 2.9 3.0 1.0 O A:THR420 3.2 4.1 1.0 C A:ILE221 3.5 2.9 1.0 CA A:ILE221 3.6 2.9 1.0 OG1 A:THR420 3.7 4.1 1.0 C A:THR420 3.9 4.1 1.0 C A:ASN220 4.0 3.0 1.0 CZ A:TYR305 4.0 5.0 1.0 CL A:CL1202 4.0 22.4 1.0 C A:PRO417 4.1 4.0 1.0 CA A:ALA418 4.2 4.2 1.0 N A:ILE221 4.3 2.9 1.0 CE1 A:TYR305 4.3 5.0 1.0 C A:ALA418 4.3 4.2 1.0 N A:THR420 4.3 4.1 1.0 O A:ALA418 4.4 4.2 1.0 CA A:THR420 4.5 4.1 1.0 N A:GLY421 4.6 4.7 1.0 N A:ALA418 4.7 4.2 1.0 N A:TRP222 4.7 3.6 1.0 OD1 A:ASN220 4.7 3.0 1.0 CB A:THR420 4.8 4.1 1.0 N A:GLY223 4.8 6.0 1.0 CB A:ILE221 4.8 2.9 1.0 N A:ALA419 4.8 4.1 1.0 CA A:GLY421 4.9 4.7 1.0 CA A:GLY223 5.0 6.0 1.0

Potassium binding site 2 out of 2 in the Cryo-Em Structure of NKCC1


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Cryo-Em Structure of NKCC1 within 5.0Å range: probe atom residue distance (Å) B Occ B:K1201 b:6.3 occ:1.00 OH B:TYR305 2.8 5.5 1.0 O B:ILE221 2.8 5.0 1.0 O B:PRO417 2.9 4.1 1.0 O B:THR420 2.9 4.2 1.0 O B:ASN220 3.1 6.4 1.0 C B:ILE221 3.6 5.0 1.0 CA B:ILE221 3.6 5.0 1.0 C B:THR420 3.8 4.2 1.0 OG1 B:THR420 3.9 4.2 1.0 CL B:CL1202 3.9 26.2 1.0 C B:PRO417 4.0 4.1 1.0 CZ B:TYR305 4.0 5.5 1.0 CA B:ALA418 4.0 4.4 1.0 C B:ALA418 4.1 4.4 1.0 O B:ALA418 4.1 4.4 1.0 C B:ASN220 4.1 6.4 1.0 N B:THR420 4.3 4.2 1.0 N B:ILE221 4.4 5.0 1.0 CE1 B:TYR305 4.4 5.5 1.0 CA B:THR420 4.5 4.2 1.0 N B:ALA418 4.5 4.4 1.0 N B:GLY421 4.6 5.8 1.0 N B:ALA419 4.7 4.2 1.0 N B:TRP222 4.8 5.2 1.0 CB B:ILE221 4.8 5.0 1.0 CB B:THR420 4.8 4.2 1.0 CA B:GLY421 4.8 5.8 1.0 N B:GLY223 4.8 5.4 1.0 CG2 B:ILE221 4.9 5.0 1.0 C B:ALA419 5.0 4.2 1.0

T.A.Chew, B.J.Orlando, J.Zhang, N.R.Latorraca, A.Wang, S.A.Hollingsworth, D.H.Chen, R.O.Dror, M.Liao, L.Feng. Structure and Mechanism of the Cation-Chloride Cotransporter NKCC1. Nature V. 572 488 2019.
ISSN: ESSN 1476-4687
PubMed: 31367042
DOI: 10.1038/S41586-019-1438-2