Atomistry » Potassium » PDB 6bd3-6csr » 6cq9
Atomistry »
  Potassium »
    PDB 6bd3-6csr »
      6cq9 »

Potassium in PDB 6cq9: K2P2.1(Trek-1):ML402 Complex

Protein crystallography data

The structure of K2P2.1(Trek-1):ML402 Complex, PDB code: 6cq9 was solved by M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 15.00 / 2.80
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 67.091, 119.565, 127.215, 90.00, 90.00, 90.00
R / Rfree (%) 26.5 / 30.9

Other elements in 6cq9:

The structure of K2P2.1(Trek-1):ML402 Complex also contains other interesting chemical elements:

Cadmium (Cd) 1 atom
Chlorine (Cl) 2 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the K2P2.1(Trek-1):ML402 Complex (pdb code 6cq9). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 5 binding sites of Potassium where determined in the K2P2.1(Trek-1):ML402 Complex, PDB code: 6cq9:
Jump to Potassium binding site number: 1; 2; 3; 4; 5;

Potassium binding site 1 out of 5 in 6cq9

Go back to Potassium Binding Sites List in 6cq9
Potassium binding site 1 out of 5 in the K2P2.1(Trek-1):ML402 Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of K2P2.1(Trek-1):ML402 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K401

b:0.5
occ:1.00
 OG1 A:THR142 4.3 0.7 1.0
OG1 A:THR251 4.5 0.1 1.0
K B:K402 4.7 0.9 1.0
OG1 B:THR251 4.8 89.4 1.0

Potassium binding site 2 out of 5 in 6cq9

Go back to Potassium Binding Sites List in 6cq9
Potassium binding site 2 out of 5 in the K2P2.1(Trek-1):ML402 Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of K2P2.1(Trek-1):ML402 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K402

b:0.7
occ:1.00
 O A:GLY144 2.6 99.3 1.0
O B:GLY253 2.6 0.0 1.0
O A:ILE143 2.7 0.6 1.0
O B:GLY144 2.7 0.8 1.0
O A:GLY253 2.7 85.2 1.0
O A:ILE252 2.7 76.0 1.0
O B:ILE252 2.8 0.0 1.0
O B:ILE143 2.9 94.3 1.0
K B:K401 2.9 96.1 1.0
K A:K403 3.2 0.6 1.0
C B:GLY253 3.4 0.5 1.0
C A:GLY253 3.5 84.3 1.0
C A:GLY144 3.5 0.3 1.0
C B:GLY144 3.5 1.0 1.0
CA A:GLY253 3.8 81.9 1.0
C A:ILE252 3.8 93.1 1.0
CA B:GLY253 3.8 97.1 1.0
C A:ILE143 3.8 93.7 1.0
C B:ILE252 3.9 80.1 1.0
C B:ILE143 4.0 91.2 1.0
CA B:GLY144 4.0 84.2 1.0
CA A:GLY144 4.1 76.5 1.0
N A:GLY253 4.3 74.9 1.0
N A:PHE145 4.3 0.5 1.0
N B:GLY253 4.4 0.8 1.0
N A:GLY144 4.4 89.6 1.0
N B:GLY144 4.5 83.8 1.0
N B:PHE254 4.5 0.1 1.0
N A:PHE254 4.5 90.2 1.0
N B:PHE145 4.6 96.4 1.0
CA A:PHE145 4.6 0.7 1.0
O A:THR251 4.8 74.6 1.0
CA B:PHE145 4.9 96.9 1.0
C A:PHE145 4.9 0.6 1.0
CA B:PHE254 5.0 0.9 1.0

Potassium binding site 3 out of 5 in 6cq9

Go back to Potassium Binding Sites List in 6cq9
Potassium binding site 3 out of 5 in the K2P2.1(Trek-1):ML402 Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of K2P2.1(Trek-1):ML402 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K403

b:0.6
occ:1.00
 O A:PHE145 2.7 0.1 1.0
O A:GLY253 2.7 85.2 1.0
O B:PHE254 2.8 0.1 1.0
O B:GLY253 2.8 0.0 1.0
O B:GLY144 2.9 0.8 1.0
O A:GLY144 3.0 99.3 1.0
O A:PHE254 3.1 95.7 1.0
O B:PHE145 3.2 0.7 1.0
K A:K402 3.2 0.7 1.0
C A:PHE145 3.3 0.6 1.0
C B:PHE145 3.5 94.7 1.0
C B:PHE254 3.6 0.8 1.0
C A:PHE254 3.6 86.3 1.0
CA A:PHE145 3.8 0.7 1.0
C A:GLY253 3.9 84.3 1.0
C B:GLY253 4.0 0.5 1.0
C B:GLY144 4.0 1.0 1.0
N B:GLY146 4.0 96.9 1.0
C A:GLY144 4.1 0.3 1.0
N A:GLY146 4.1 0.7 1.0
CA B:PHE254 4.1 0.9 1.0
CA B:PHE145 4.1 96.9 1.0
CA A:PHE254 4.1 75.8 1.0
CA B:GLY146 4.3 89.3 1.0
CA A:GLY146 4.4 0.4 1.0
N A:GLY255 4.4 0.8 1.0
N A:PHE145 4.4 0.5 1.0
N A:PHE254 4.5 90.2 1.0
N B:PHE254 4.5 0.1 1.0
N B:GLY255 4.6 0.4 1.0
N B:PHE145 4.6 96.4 1.0
CA A:GLY255 4.9 0.8 1.0
CA B:GLY255 5.0 94.7 1.0

Potassium binding site 4 out of 5 in 6cq9

Go back to Potassium Binding Sites List in 6cq9
Potassium binding site 4 out of 5 in the K2P2.1(Trek-1):ML402 Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of K2P2.1(Trek-1):ML402 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K401

b:96.1
occ:1.00
 O A:THR251 2.6 74.6 1.0
O B:ILE252 2.6 0.0 1.0
O A:ILE252 2.7 76.0 1.0
O A:THR142 2.8 0.9 1.0
O B:THR251 2.8 93.7 1.0
O A:ILE143 2.8 0.6 1.0
O B:THR142 2.9 81.5 1.0
O B:ILE143 2.9 94.3 1.0
K A:K402 2.9 0.7 1.0
C B:ILE252 3.4 80.1 1.0
C A:ILE252 3.5 93.1 1.0
C A:ILE143 3.5 93.7 1.0
C B:ILE143 3.6 91.2 1.0
K B:K402 3.7 0.9 1.0
C A:THR251 3.8 87.6 1.0
C B:THR251 3.8 87.8 1.0
C A:THR142 3.9 95.1 1.0
C B:THR142 3.9 57.3 1.0
CA A:ILE143 4.0 95.6 1.0
CA B:ILE143 4.0 85.8 1.0
CA B:ILE252 4.0 0.7 1.0
CA A:ILE252 4.1 71.0 1.0
N B:GLY253 4.3 0.8 1.0
N B:ILE252 4.4 0.4 1.0
N A:ILE252 4.4 58.9 1.0
N A:ILE143 4.4 86.4 1.0
N B:ILE143 4.4 77.5 1.0
N A:GLY253 4.5 74.9 1.0
N B:GLY144 4.5 83.8 1.0
N A:GLY144 4.5 89.6 1.0
CA B:GLY253 4.5 97.1 1.0
CA A:GLY253 4.7 81.9 1.0
O A:GLY144 4.8 99.3 1.0
CA B:GLY144 4.8 84.2 1.0
O B:GLY253 4.8 0.0 1.0
CA A:THR251 4.9 81.3 1.0
O B:GLY144 4.9 0.8 1.0
CA A:GLY144 4.9 76.5 1.0
CA B:THR251 5.0 85.3 1.0

Potassium binding site 5 out of 5 in 6cq9

Go back to Potassium Binding Sites List in 6cq9
Potassium binding site 5 out of 5 in the K2P2.1(Trek-1):ML402 Complex


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of K2P2.1(Trek-1):ML402 Complex within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K402

b:0.9
occ:1.00
 O B:THR142 2.8 81.5 1.0
O B:THR251 2.8 93.7 1.0
OG1 A:THR251 2.9 0.1 1.0
O A:THR142 2.9 0.9 1.0
O A:THR251 3.0 74.6 1.0
OG1 B:THR142 3.1 87.6 1.0
OG1 B:THR251 3.2 89.4 1.0
CB A:THR251 3.2 79.1 1.0
CB B:THR251 3.3 73.3 1.0
OG1 A:THR142 3.3 0.7 1.0
CB B:THR142 3.5 62.9 1.0
CB A:THR142 3.6 0.3 1.0
K B:K401 3.7 96.1 1.0
C B:THR142 3.8 57.3 1.0
C A:THR251 3.8 87.6 1.0
C B:THR251 3.8 87.8 1.0
C A:THR142 3.9 95.1 1.0
CA A:THR251 4.1 81.3 1.0
CA B:THR251 4.2 85.3 1.0
CA B:THR142 4.3 63.4 1.0
CG2 A:THR251 4.4 84.6 1.0
CA A:THR142 4.4 85.1 1.0
CG2 B:THR251 4.5 72.7 1.0
CG2 B:THR142 4.7 59.9 1.0
K A:K401 4.7 0.5 1.0
O A:THR250 4.7 90.8 1.0
N A:ILE252 4.8 58.9 1.0
O B:THR141 4.8 91.6 1.0
CG2 A:THR142 4.8 0.0 1.0
N B:ILE143 4.8 77.5 1.0
N B:ILE252 4.9 0.4 1.0
N A:ILE143 4.9 86.4 1.0
O B:THR250 5.0 87.8 1.0

Reference:

M.Lolicato, C.Arrigoni, T.Mori, Y.Sekioka, C.Bryant, K.A.Clark, D.L.Minor. K2P2.1 (Trek-1)-Activator Complexes Reveal A Cryptic Selectivity Filter Binding Site. Nature V. 547 364 2017.
ISSN: ESSN 1476-4687
PubMed: 28693035
DOI: 10.1038/NATURE22988
Page generated: Mon Dec 14 00:27:25 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy