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Potassium in PDB 6c07: Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum

Enzymatic activity of Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum

All present enzymatic activity of Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum:
2.5.1.6;

Protein crystallography data

The structure of Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum, PDB code: 6c07 was solved by J.F.Ohren, R.E.Viola, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.99 / 1.85
Space group I 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 134.390, 62.060, 191.583, 90.00, 90.65, 90.00
R / Rfree (%) 15.7 / 20.4

Other elements in 6c07:

The structure of Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum also contains other interesting chemical elements:

Magnesium (Mg) 7 atoms
Chlorine (Cl) 2 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum (pdb code 6c07). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum, PDB code: 6c07:

Potassium binding site 1 out of 1 in 6c07

Go back to Potassium Binding Sites List in 6c07
Potassium binding site 1 out of 1 in the Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of S-Adenosylmethionine Synthetase (Metk/Mat) From Cryptosporidium Parvum within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K501

b:23.3
occ:0.48
O D:GLY271 2.7 22.6 1.0
O C:GLY271 2.8 18.3 1.0
O D:HOH776 2.8 33.6 1.0
HD13 D:ILE274 2.9 23.4 1.0
O D:HOH709 2.9 20.7 1.0
HA C:ARG272 2.9 23.2 1.0
HG23 C:ILE274 3.1 22.7 1.0
HD2 C:ARG272 3.2 26.1 1.0
HG23 D:ILE274 3.3 27.9 1.0
HA D:ARG272 3.4 22.2 1.0
HG21 D:ILE274 3.5 27.9 1.0
HD2 D:ARG272 3.5 23.8 1.0
HD13 C:ILE274 3.5 32.4 1.0
HG12 D:ILE274 3.6 25.4 1.0
CD1 D:ILE274 3.8 19.4 1.0
CG2 D:ILE274 3.8 23.3 1.0
HG12 C:ILE274 3.8 21.3 1.0
C C:GLY271 3.8 16.2 1.0
CA C:ARG272 3.9 19.3 1.0
HG21 C:ILE274 3.9 22.7 1.0
C D:GLY271 3.9 17.7 1.0
CG2 C:ILE274 3.9 18.9 1.0
CD C:ARG272 4.1 21.7 1.0
CG1 D:ILE274 4.1 21.1 1.0
HD11 D:ILE274 4.2 23.4 1.0
N C:ARG272 4.3 15.4 1.0
H C:ILE274 4.3 23.9 1.0
CA D:ARG272 4.3 18.5 1.0
CD1 C:ILE274 4.3 27.0 1.0
H D:ILE274 4.4 24.8 1.0
HD3 C:ARG272 4.4 26.1 1.0
HD12 D:ILE274 4.4 23.4 1.0
CD D:ARG272 4.4 19.9 1.0
CG1 C:ILE274 4.5 17.7 1.0
C C:ARG272 4.5 21.6 1.0
HG22 C:ILE274 4.6 22.7 1.0
N D:ARG272 4.6 15.7 1.0
CB D:ILE274 4.6 17.0 1.0
HG2 C:ARG272 4.6 22.8 1.0
HG22 D:ILE274 4.6 27.9 1.0
O C:HOH749 4.7 31.4 1.0
HD11 C:ILE274 4.7 32.4 1.0
HD3 D:ARG272 4.7 23.8 1.0
CG C:ARG272 4.8 19.0 1.0
O D:GLY287 4.8 27.9 1.0
CB C:ILE274 4.8 20.7 1.0
HB2 D:ALA289 4.8 31.9 1.0
CB C:ARG272 4.8 21.5 1.0
HA3 D:GLY271 4.9 22.4 1.0
HG2 D:ARG272 4.9 26.9 1.0
HE C:ARG272 4.9 26.8 1.0
HB2 C:ALA289 4.9 28.5 1.0
N C:LYS273 5.0 21.6 1.0
C D:ARG272 5.0 24.6 1.0
HG13 D:ILE274 5.0 25.4 1.0
H C:LYS273 5.0 26.0 1.0

Reference:

J.Ohren, G.G.Parungao, R.E.Viola. Structure of A Critical Metabolic Enzyme: S-Adenosylmethionine Synthetase From Cryptosporidium Parvum. Acta Crystallogr F Struct V. 75 290 2019BIOL Commun.
ISSN: ESSN 2053-230X
PubMed: 30950830
DOI: 10.1107/S2053230X19002772
Page generated: Mon Aug 12 15:28:27 2024

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