Potassium in PDB 8wa5: Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State

The structure of Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State also contains other interesting chemical elements:

Aluminium	(Al)	1 atom
Fluorine	(F)	4 atoms
Magnesium	(Mg)	1 atom

The binding sites of Potassium atom in the Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State (pdb code 8wa5). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State, PDB code: 8wa5:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:K1101 b:33.2 occ:1.00 O A:ALA339 2.7 33.2 1.0 O A:VAL341 2.7 33.2 1.0 OE2 A:GLU795 2.7 33.2 1.0 OE1 A:GLU343 3.0 33.2 1.0 O A:VAL338 3.0 33.2 1.0 CD A:GLU820 3.3 33.2 1.0 ND2 A:ASN792 3.3 33.2 1.0 OE1 A:GLU820 3.4 33.2 1.0 C A:ALA339 3.4 33.2 1.0 OE2 A:GLU820 3.5 33.2 1.0 C A:VAL341 3.7 33.2 1.0 CG A:GLU820 3.8 33.2 1.0 CD A:GLU795 3.8 33.2 1.0 CA A:ALA339 3.9 33.2 1.0 CG2 A:ILE816 4.0 33.2 1.0 CD A:GLU343 4.0 33.2 1.0 C A:VAL338 4.1 33.2 1.0 C A:TYR340 4.2 33.2 1.0 N A:VAL341 4.2 33.2 1.0 OE2 A:GLU343 4.3 33.2 1.0 N A:TYR340 4.3 33.2 1.0 CG A:ASN792 4.3 33.2 1.0 O A:TYR340 4.3 33.2 1.0 N A:PRO342 4.5 33.2 1.0 CA A:PRO342 4.5 33.2 1.0 N A:ALA339 4.5 33.2 1.0 CA A:VAL341 4.6 33.2 1.0 CG A:GLU795 4.6 33.2 1.0 OE1 A:GLU795 4.6 33.2 1.0 CA A:TYR340 4.7 33.2 1.0 CB A:GLU820 4.7 33.2 1.0 N A:GLU343 4.7 33.2 1.0 CB A:ASN792 4.9 33.2 1.0

Potassium binding site 2 out of 3 in the Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:K1102 b:38.5 occ:1.00 O A:ALA737 2.6 33.2 1.0 O A:LEU734 2.7 33.2 1.0 O A:LYS735 3.0 34.7 1.0 OD2 A:ASP756 3.1 33.2 1.0 C A:LYS735 3.5 34.7 1.0 C A:ALA737 3.7 33.2 1.0 C A:LEU734 3.8 33.2 1.0 CA A:LYS735 3.9 34.7 1.0 N A:ALA737 4.1 33.2 1.0 N A:GLY740 4.1 33.2 1.0 CG A:ASP756 4.2 33.2 1.0 O A:ASP738 4.3 33.2 1.0 CA A:ALA737 4.3 33.2 1.0 N A:LYS735 4.4 34.7 1.0 C A:LYS736 4.4 34.5 1.0 N A:LYS736 4.4 34.5 1.0 C A:ASP738 4.5 33.2 1.0 CA A:GLY740 4.6 33.2 1.0 C A:ILE739 4.7 33.2 1.0 K A:K1103 4.7 48.2 1.0 CB A:ALA737 4.7 33.2 1.0 O A:ALA754 4.7 33.8 1.0 N A:ASP738 4.7 33.2 1.0 N A:ILE739 4.8 33.2 1.0 OD1 A:ASP756 4.8 33.2 1.0 O A:LYS736 4.9 34.5 1.0 CA A:ILE739 4.9 33.2 1.0 CA A:ASP738 4.9 33.2 1.0 CA A:LYS736 4.9 34.5 1.0

Potassium binding site 3 out of 3 in the Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Cryo-Em Structure of the Gastric Proton Pump Y799W/E936Q Mutant in K+- Occluded (K+)E2-Alf State within 5.0Å range: probe atom residue distance (Å) B Occ A:K1103 b:48.2 occ:1.00 O A:LYS736 3.0 34.5 1.0 O A:ALA737 3.4 33.2 1.0 C A:LYS736 3.9 34.5 1.0 C A:ALA737 4.0 33.2 1.0 O A:LYS735 4.0 34.7 1.0 CB A:GLU289 4.0 58.7 1.0 CG A:GLU289 4.1 58.7 1.0 O A:GLU289 4.2 58.7 1.0 CA A:ASP738 4.3 33.2 1.0 N A:GLU289 4.3 58.7 1.0 N A:ASP738 4.4 33.2 1.0 CA A:LYS736 4.5 34.5 1.0 O A:GLU287 4.5 63.9 1.0 CA A:GLU289 4.6 58.7 1.0 K A:K1102 4.7 38.5 1.0 N A:ALA737 4.7 33.2 1.0 OD1 A:ASP738 4.7 33.2 1.0 C A:GLU289 4.8 58.7 1.0 NE2 A:GLN715 4.8 34.6 1.0 CA A:ALA737 4.9 33.2 1.0

H.V.Madapally, K.Abe, V.Dubey, H.Khandelia. Specific Protonation of Acidic Residues Confers K+ Selectivity to the Gastric Proton Pump. To Be Published.