Potassium in PDB 8gjb: L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate

All present enzymatic activity of L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate:
1.1.1.103;

The structure of L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate, PDB code: 8gjb was solved by G.F.Mercaldi, J.N.Faria, M.Fagundes, E.H.S.Bezerra, A.T.Cordeiro, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.32 / 1.75
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	47.274, 82.733, 84.384, 90, 90.45, 90
R / Rfree (%)	18 / 21

The binding sites of Potassium atom in the L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate (pdb code 8gjb). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate, PDB code: 8gjb:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate within 5.0Å range: probe atom residue distance (Å) B Occ A:K403 b:50.4 occ:1.00 OE2 A:GLU221 2.7 22.6 1.0 O A:PRO222 2.8 20.4 1.0 O A:TRP291 2.9 18.0 1.0 OD1 A:ASP293 2.9 21.7 1.0 O A:ALA288 3.0 18.4 1.0 O A:PRO292 3.2 18.0 1.0 O A:HOH526 3.5 32.1 1.0 C A:PRO292 3.6 19.3 1.0 CD A:GLU221 3.8 23.2 1.0 C A:TRP291 3.8 19.6 1.0 N A:ASP293 3.9 21.3 1.0 CD2 A:LEU223 4.0 19.8 1.0 CA A:ASP293 4.0 21.5 1.0 C A:PRO222 4.1 20.2 1.0 C A:ALA288 4.1 21.6 1.0 CG A:ASP293 4.1 23.4 1.0 CE A:LYS140 4.2 32.1 1.0 CG A:GLU221 4.2 21.9 1.0 O A:HIS289 4.4 23.5 1.0 CA A:HIS289 4.4 21.0 1.0 CD A:PRO222 4.5 22.3 1.0 C A:HIS289 4.5 23.1 1.0 CA A:PRO292 4.5 18.8 1.0 N A:TRP291 4.6 19.7 1.0 N A:PRO292 4.6 16.8 1.0 CA A:TRP291 4.6 18.8 1.0 CB A:ASP293 4.6 20.8 1.0 N A:PRO222 4.7 21.5 1.0 N A:HIS289 4.7 19.7 1.0 CB A:TRP291 4.7 18.5 1.0 CG A:LEU223 4.7 20.4 1.0 NZ A:LYS140 4.8 30.3 1.0 OE1 A:GLU221 4.8 22.4 1.0 CA A:PRO222 4.9 20.0 1.0 CA A:LEU223 4.9 20.1 1.0 N A:LEU223 5.0 18.7 1.0

Potassium binding site 2 out of 2 in the L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi in Complex with Nad and Acetate within 5.0Å range: probe atom residue distance (Å) B Occ B:K403 b:47.1 occ:1.00 O B:PRO222 2.7 18.8 1.0 OE2 B:GLU221 2.8 22.0 1.0 OD1 B:ASP293 2.8 25.8 1.0 O B:TRP291 2.9 19.2 1.0 O B:PRO292 3.0 17.2 1.0 O B:ALA288 3.1 18.0 1.0 O B:HOH510 3.5 29.3 1.0 C B:PRO292 3.6 18.1 1.0 N B:ASP293 3.8 17.8 1.0 C B:TRP291 3.8 19.2 1.0 CD B:GLU221 3.8 21.6 1.0 CA B:ASP293 3.9 20.0 1.0 CD2 B:LEU223 3.9 18.0 1.0 C B:PRO222 4.0 18.0 1.0 CG B:ASP293 4.0 25.2 1.0 CG B:GLU221 4.2 22.6 1.0 CE B:LYS140 4.2 27.0 1.0 C B:ALA288 4.2 19.1 1.0 O B:HIS289 4.5 21.2 1.0 CA B:HIS289 4.5 19.9 1.0 CB B:ASP293 4.5 21.7 1.0 CA B:PRO292 4.5 18.6 1.0 CD B:PRO222 4.6 17.0 1.0 N B:PRO292 4.6 18.3 1.0 CG B:LEU223 4.6 19.3 1.0 N B:TRP291 4.6 19.8 1.0 CA B:TRP291 4.6 18.8 1.0 C B:HIS289 4.7 20.9 1.0 NZ B:LYS140 4.7 32.1 1.0 N B:PRO222 4.7 18.1 1.0 CG B:PRO222 4.7 20.0 1.0 CB B:TRP291 4.8 17.7 1.0 CA B:LEU223 4.8 17.9 1.0 N B:HIS289 4.8 19.3 1.0 N B:LEU223 4.9 16.4 1.0 CA B:PRO222 4.9 18.1 1.0 OE1 B:GLU221 4.9 24.9 1.0

J.N.Faria, G.F.Mercaldi, M.Fagundes, A.G.Eufrasio, A.T.Cordeiro. Structure, Allosteric Regulation and Metabolic Activity of L-Threonine 3-Dehydrogenase From Trypanosoma Cruzi To Be Published.