Potassium in PDB 7ukg: Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region

Potassium Binding Sites:

The binding sites of Potassium atom in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region (pdb code 7ukg). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region, PDB code: 7ukg:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 7ukg

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Potassium Binding Sites List in 7ukg

Potassium binding site 1 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region

Mono view

Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:K601 b:24.0 occ:1.00	OG1	A:THR370	3.0	22.4	1.0
	OG1	D:THR370	3.0	22.3	1.0
	OG1	C:THR370	3.0	22.3	1.0
	OG1	B:THR370	3.0	22.4	1.0
	O	D:THR370	3.0	22.3	1.0
	O	C:THR370	3.0	22.3	1.0
	O	B:THR370	3.0	22.4	1.0
	O	A:THR370	3.1	22.4	1.0
	K	A:K602	3.4	17.7	1.0
	CB	A:THR370	3.7	22.4	1.0
	CB	D:THR370	3.7	22.3	1.0
	CB	C:THR370	3.7	22.3	1.0
	CB	B:THR370	3.7	22.4	1.0
	C	D:THR370	4.0	22.3	1.0
	C	C:THR370	4.0	22.3	1.0
	C	B:THR370	4.0	22.4	1.0
	C	A:THR370	4.0	22.4	1.0
	CA	D:THR370	4.5	22.3	1.0
	CA	C:THR370	4.5	22.3	1.0
	CA	B:THR370	4.5	22.4	1.0
	CA	A:THR370	4.5	22.4	1.0
	O	A:THR369	4.8	23.1	1.0
	O	D:THR369	4.8	23.0	1.0
	O	C:THR369	4.8	22.9	1.0
	O	B:THR369	4.8	23.1	1.0
	CG2	A:THR370	4.8	22.4	1.0
	CG2	D:THR370	4.9	22.3	1.0
	CG2	C:THR370	4.9	22.3	1.0
	CG2	B:THR370	4.9	22.4	1.0

Potassium binding site 2 out of 4 in 7ukg

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Potassium Binding Sites List in 7ukg

Potassium binding site 2 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region

Mono view

Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:K602 b:17.7 occ:1.00	O	A:THR370	2.7	22.4	1.0
	O	D:THR370	2.7	22.3	1.0
	O	C:THR370	2.7	22.3	1.0
	O	B:THR370	2.7	22.4	1.0
	O	D:LEU371	2.8	20.1	1.0
	O	B:LEU371	2.8	20.3	1.0
	O	C:LEU371	2.8	20.2	1.0
	O	A:LEU371	2.9	20.2	1.0
	K	A:K603	3.3	15.9	1.0
	K	A:K601	3.4	24.0	1.0
	C	D:LEU371	3.6	20.1	1.0
	C	C:LEU371	3.6	20.2	1.0
	C	B:LEU371	3.6	20.3	1.0
	C	A:LEU371	3.6	20.2	1.0
	C	A:THR370	3.8	22.4	1.0
	C	D:THR370	3.8	22.3	1.0
	C	C:THR370	3.8	22.3	1.0
	C	B:THR370	3.8	22.4	1.0
	CA	D:LEU371	4.0	20.1	1.0
	CA	C:LEU371	4.0	20.2	1.0
	CA	B:LEU371	4.0	20.3	1.0
	CA	A:LEU371	4.0	20.2	1.0
	N	A:LEU371	4.4	20.2	1.0
	N	D:LEU371	4.4	20.1	1.0
	N	C:LEU371	4.4	20.2	1.0
	N	B:LEU371	4.4	20.3	1.0
	N	D:GLY372	4.5	18.7	1.0
	N	C:GLY372	4.5	18.7	1.0
	N	B:GLY372	4.5	18.6	1.0
	N	A:GLY372	4.5	18.8	1.0
	CA	D:GLY372	4.9	18.7	1.0
	CA	C:GLY372	4.9	18.7	1.0
	CA	B:GLY372	4.9	18.6	1.0
	CA	A:GLY372	5.0	18.8	1.0
	CA	A:THR370	5.0	22.4	1.0

Potassium binding site 3 out of 4 in 7ukg

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Potassium Binding Sites List in 7ukg

Potassium binding site 3 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region

Mono view

Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:K603 b:15.9 occ:1.00	O	A:LEU371	2.7	20.2	1.0
	O	B:LEU371	2.7	20.3	1.0
	O	D:LEU371	2.7	20.1	1.0
	O	C:LEU371	2.7	20.2	1.0
	O	B:GLY372	2.8	18.6	1.0
	O	D:GLY372	2.8	18.7	1.0
	O	C:GLY372	2.8	18.7	1.0
	O	A:GLY372	2.9	18.8	1.0
	K	A:K602	3.3	17.7	1.0
	K	B:K601	3.4	18.4	1.0
	C	B:GLY372	3.5	18.6	1.0
	C	D:GLY372	3.5	18.7	1.0
	C	C:GLY372	3.5	18.7	1.0
	C	A:GLY372	3.5	18.8	1.0
	C	A:LEU371	3.8	20.2	1.0
	C	B:LEU371	3.8	20.3	1.0
	C	C:LEU371	3.8	20.2	1.0
	C	D:LEU371	3.8	20.1	1.0
	CA	B:GLY372	3.9	18.6	1.0
	CA	D:GLY372	3.9	18.7	1.0
	CA	C:GLY372	3.9	18.7	1.0
	CA	A:GLY372	3.9	18.8	1.0
	N	A:GLY372	4.3	18.8	1.0
	N	B:GLY372	4.3	18.6	1.0
	N	D:GLY372	4.3	18.7	1.0
	N	C:GLY372	4.3	18.7	1.0
	N	B:TYR373	4.4	19.8	1.0
	N	D:TYR373	4.4	19.6	1.0
	N	C:TYR373	4.4	19.7	1.0
	N	A:TYR373	4.4	19.5	1.0
	CA	B:TYR373	4.8	19.8	1.0
	CA	C:TYR373	4.8	19.7	1.0
	CA	D:TYR373	4.8	19.6	1.0
	CA	A:TYR373	4.8	19.5	1.0

Potassium binding site 4 out of 4 in 7ukg

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Potassium Binding Sites List in 7ukg

Potassium binding site 4 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region

Mono view

Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
B:K601 b:18.4 occ:1.00	O	D:TYR373	2.8	19.6	1.0
	O	B:TYR373	2.8	19.8	1.0
	O	C:TYR373	2.8	19.7	1.0
	O	A:TYR373	2.9	19.5	1.0
	O	A:GLY372	3.0	18.8	1.0
	O	D:GLY372	3.0	18.7	1.0
	O	B:GLY372	3.0	18.6	1.0
	O	C:GLY372	3.0	18.7	1.0
	K	A:K603	3.4	15.9	1.0
	C	D:TYR373	3.5	19.6	1.0
	C	B:TYR373	3.5	19.8	1.0
	C	C:TYR373	3.5	19.7	1.0
	C	A:TYR373	3.5	19.5	1.0
	CA	B:TYR373	4.1	19.8	1.0
	CA	D:TYR373	4.1	19.6	1.0
	CA	C:TYR373	4.1	19.7	1.0
	CA	A:TYR373	4.1	19.5	1.0
	C	A:GLY372	4.1	18.8	1.0
	C	D:GLY372	4.1	18.7	1.0
	C	B:GLY372	4.1	18.6	1.0
	C	C:GLY372	4.1	18.7	1.0
	N	D:GLY374	4.3	20.2	1.0
	N	B:GLY374	4.3	20.3	1.0
	N	C:GLY374	4.3	20.3	1.0
	N	A:GLY374	4.3	20.3	1.0
	N	D:TYR373	4.6	19.6	1.0
	N	B:TYR373	4.6	19.8	1.0
	N	A:TYR373	4.6	19.5	1.0
	N	C:TYR373	4.6	19.7	1.0
	CA	D:GLY374	4.6	20.2	1.0
	CA	C:GLY374	4.6	20.3	1.0
	CA	B:GLY374	4.6	20.3	1.0
	CA	A:GLY374	4.7	20.3	1.0

Reference:

W.Ye, H.Zhao, Y.Dai, Y.Wang, Y.H.Lo, L.Y.Jan, C.H.Lee. Activation and Closed-State Inactivation Mechanisms of the Human Voltage-Gated K V 4 Channel Complexes. Mol.Cell V. 82 2427 2022.
ISSN: ISSN 1097-2765
PubMed: 35597238
DOI: 10.1016/J.MOLCEL.2022.04.032

Page generated: Sat Aug 9 15:04:43 2025

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