Potassium in PDB 6w7e: K2P2.1 (Trek-1), 30 Mm K+

The structure of K2P2.1 (Trek-1), 30 Mm K+, PDB code: 6w7e was solved by M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	14.94 / 3.29
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	67.368, 122.534, 126.552, 90, 90, 90
R / Rfree (%)	28.8 / 30.7

The structure of K2P2.1 (Trek-1), 30 Mm K+ also contains other interesting chemical elements:

Cadmium

(Cd)

4 atoms

The binding sites of Potassium atom in the K2P2.1 (Trek-1), 30 Mm K+ (pdb code 6w7e). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the K2P2.1 (Trek-1), 30 Mm K+, PDB code: 6w7e:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the K2P2.1 (Trek-1), 30 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of K2P2.1 (Trek-1), 30 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ A:K406 b:155.2 occ:1.00 O A:ILE252 2.8 174.8 1.0 O B:ILE252 2.8 166.2 1.0 O B:THR142 2.8 128.1 1.0 O A:THR142 2.8 135.4 1.0 O B:THR251 2.9 153.3 1.0 O A:ILE143 3.0 157.9 1.0 O B:ILE143 3.0 150.4 1.0 O A:THR251 3.0 148.8 1.0 C A:ILE252 3.3 180.8 1.0 C B:ILE252 3.5 166.5 1.0 K B:K407 3.7 136.6 1.0 C A:ILE143 3.8 164.2 1.0 C B:ILE143 3.8 157.4 1.0 N A:GLY253 3.9 203.4 1.0 C B:THR251 3.9 152.0 1.0 CA B:ILE252 3.9 157.0 1.0 C A:THR142 4.0 135.6 1.0 C B:THR142 4.0 130.0 1.0 C A:THR251 4.0 152.4 1.0 CA A:GLY253 4.1 224.8 1.0 CA A:ILE252 4.1 162.4 1.0 CA B:ILE143 4.2 140.9 1.0 CA A:ILE143 4.2 154.6 1.0 N B:ILE252 4.4 153.3 1.0 N B:GLY253 4.4 176.7 1.0 N A:ILE252 4.5 156.2 1.0 N B:ILE143 4.6 137.1 1.0 N A:ILE143 4.6 144.8 1.0 CA B:GLY253 4.8 183.8 1.0 N A:GLY144 4.8 184.2 1.0 O A:GLY144 4.9 212.9 1.0 N B:GLY144 4.9 178.6 1.0

Potassium binding site 2 out of 2 in the K2P2.1 (Trek-1), 30 Mm K+


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of K2P2.1 (Trek-1), 30 Mm K+ within 5.0Å range: probe atom residue distance (Å) B Occ B:K407 b:136.6 occ:1.00 O B:THR251 2.7 153.3 1.0 O A:THR251 2.8 148.8 1.0 OG1 B:THR251 2.9 154.4 1.0 OG1 B:THR142 3.0 133.1 1.0 O B:THR142 3.1 128.1 1.0 O A:THR142 3.2 135.4 1.0 CB B:THR251 3.3 148.5 1.0 OG1 A:THR142 3.3 130.2 1.0 OG1 A:THR251 3.3 153.2 1.0 CB B:THR142 3.6 129.6 1.0 CB A:THR142 3.7 126.0 1.0 CB A:THR251 3.7 148.3 1.0 K A:K406 3.7 155.2 1.0 C B:THR251 3.7 152.0 1.0 C A:THR251 3.9 152.4 1.0 C B:THR142 3.9 130.0 1.0 C A:THR142 4.1 135.6 1.0 CA B:THR251 4.1 151.1 1.0 CA A:THR251 4.4 146.4 1.0 CA B:THR142 4.4 129.6 1.0 CG2 B:THR251 4.5 146.0 1.0 CA A:THR142 4.5 131.6 1.0 O B:THR141 4.7 130.1 1.0 N B:ILE143 4.8 137.1 1.0 CG2 A:THR142 4.8 126.1 1.0 O B:THR250 4.8 150.5 1.0 N B:ILE252 4.9 153.3 1.0 CG2 B:THR142 4.9 130.9 1.0 N A:ILE252 4.9 156.2 1.0 CG2 A:THR251 4.9 146.3 1.0

M.Lolicato, A.M.Natale, F.Abderemane-Ali, D.Crottes, S.Capponi, R.Duman, A.Wagner, J.M.Rosenberg, M.Grabe, D.L.Minor Jr.. K 2P Channel C-Type Gating Involves Asymmetric Selectivity Filter Order-Disorder Transitions. Sci Adv V. 6 2020.
ISSN: ESSN 2375-2548
PubMed: 33127683
DOI: 10.1126/SCIADV.ABC9174