Atomistry » Potassium » PDB 6u9t-6v7h » 6v36
Atomistry »
  Potassium »
    PDB 6u9t-6v7h »
      6v36 »

Potassium in PDB 6v36: K2P2.1(Trek-1)I110D Apo Channel Structure

Protein crystallography data

The structure of K2P2.1(Trek-1)I110D Apo Channel Structure, PDB code: 6v36 was solved by L.Pope, M.Lolicato, D.L.Minor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 14.98 / 3.40
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 68.192, 120.400, 128.355, 90.00, 90.00, 90.00
R / Rfree (%) 28.6 / 31.8

Other elements in 6v36:

The structure of K2P2.1(Trek-1)I110D Apo Channel Structure also contains other interesting chemical elements:

Cadmium (Cd) 3 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the K2P2.1(Trek-1)I110D Apo Channel Structure (pdb code 6v36). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 6 binding sites of Potassium where determined in the K2P2.1(Trek-1)I110D Apo Channel Structure, PDB code: 6v36:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6;

Potassium binding site 1 out of 6 in 6v36

Go back to Potassium Binding Sites List in 6v36
Potassium binding site 1 out of 6 in the K2P2.1(Trek-1)I110D Apo Channel Structure


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of K2P2.1(Trek-1)I110D Apo Channel Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K405

b:0.7
occ:1.00
 O A:GLY146 4.3 0.5 1.0
OD1 A:ASP110 4.7 0.0 1.0
C A:GLY146 4.9 0.2 1.0

Potassium binding site 2 out of 6 in 6v36

Go back to Potassium Binding Sites List in 6v36
Potassium binding site 2 out of 6 in the K2P2.1(Trek-1)I110D Apo Channel Structure


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of K2P2.1(Trek-1)I110D Apo Channel Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K406

b:0.7
occ:1.00
 OG1 A:THR251 2.4 0.9 1.0
O B:THR251 2.5 0.9 1.0
OG1 B:THR251 2.6 0.2 1.0
O A:THR251 2.7 0.3 1.0
O A:THR142 2.7 0.3 1.0
OG1 A:THR142 2.8 0.9 1.0
CB A:THR142 3.3 0.8 1.0
K A:K407 3.3 0.3 1.0
O B:THR142 3.3 0.3 1.0
C A:THR142 3.5 0.3 1.0
CB A:THR251 3.6 0.9 1.0
C B:THR251 3.7 1.0 1.0
OG1 B:THR142 3.7 0.6 1.0
C A:THR251 3.8 0.6 1.0
CB B:THR251 3.9 0.3 1.0
CA A:THR142 4.0 1.0 1.0
CB B:THR142 4.1 0.6 1.0
C B:THR142 4.3 0.2 1.0
CA A:THR251 4.4 0.1 1.0
CA B:THR251 4.4 0.5 1.0
N A:ILE143 4.5 0.1 1.0
O A:THR141 4.5 1.0 1.0
CG2 A:THR142 4.5 0.1 1.0
K B:K405 4.6 0.1 1.0
N B:ILE252 4.7 0.3 1.0
CG2 A:THR251 4.7 1.0 1.0
CG2 B:THR251 4.8 1.0 1.0
CA B:ILE252 4.8 0.8 1.0
CA B:THR142 4.9 0.5 1.0
CA A:ILE143 4.9 0.1 1.0
N A:ILE252 5.0 0.5 1.0

Potassium binding site 3 out of 6 in 6v36

Go back to Potassium Binding Sites List in 6v36
Potassium binding site 3 out of 6 in the K2P2.1(Trek-1)I110D Apo Channel Structure


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of K2P2.1(Trek-1)I110D Apo Channel Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K407

b:0.3
occ:1.00
 O B:THR142 2.6 0.3 1.0
O A:THR142 2.7 0.3 1.0
O A:ILE252 2.8 0.9 1.0
O A:THR251 2.8 0.3 1.0
O B:ILE143 2.8 0.5 1.0
O B:ILE252 2.9 0.7 1.0
O A:ILE143 3.0 0.4 1.0
O B:THR251 3.1 0.9 1.0
K A:K408 3.2 0.8 1.0
K A:K406 3.3 0.7 1.0
C A:ILE252 3.5 0.6 1.0
C B:ILE143 3.6 0.1 1.0
C B:ILE252 3.7 0.2 1.0
C A:ILE143 3.7 0.5 1.0
C B:THR142 3.8 0.2 1.0
C A:THR251 3.8 0.6 1.0
CA A:ILE252 3.8 0.9 1.0
C A:THR142 3.8 0.3 1.0
CA B:ILE143 4.0 0.1 1.0
CA A:ILE143 4.0 0.1 1.0
C B:THR251 4.1 1.0 1.0
CA B:ILE252 4.1 0.8 1.0
N A:ILE252 4.3 0.5 1.0
N B:ILE143 4.4 0.5 1.0
N A:ILE143 4.4 0.1 1.0
N B:ILE252 4.5 0.3 1.0
OG1 A:THR251 4.5 0.9 1.0
OG1 B:THR251 4.6 0.2 1.0
N A:GLY253 4.6 0.5 1.0
N B:GLY144 4.7 0.6 1.0
N B:GLY253 4.8 0.7 1.0
N A:GLY144 4.9 0.3 1.0
CA B:THR142 5.0 0.5 1.0
CA A:THR251 5.0 0.1 1.0

Potassium binding site 4 out of 6 in 6v36

Go back to Potassium Binding Sites List in 6v36
Potassium binding site 4 out of 6 in the K2P2.1(Trek-1)I110D Apo Channel Structure


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of K2P2.1(Trek-1)I110D Apo Channel Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K408

b:0.8
occ:1.00
 O B:GLY253 2.7 0.3 1.0
O A:ILE143 2.7 0.4 1.0
O A:ILE252 2.7 0.9 1.0
O A:GLY253 2.8 0.7 1.0
O B:GLY144 2.8 0.2 1.0
O B:ILE143 2.8 0.5 1.0
O B:ILE252 2.8 0.7 1.0
O A:GLY144 2.8 0.2 1.0
K A:K409 2.9 0.8 0.4
K A:K407 3.2 0.3 1.0
C B:GLY253 3.6 0.6 1.0
C B:GLY144 3.6 0.6 1.0
C A:GLY253 3.6 0.9 1.0
C A:GLY144 3.7 0.2 1.0
C A:ILE143 3.9 0.5 1.0
C A:ILE252 3.9 0.6 1.0
C B:ILE143 4.0 0.1 1.0
C B:ILE252 4.0 0.2 1.0
CA B:GLY253 4.2 0.1 1.0
CA A:GLY253 4.2 0.8 1.0
CA A:GLY144 4.3 0.5 1.0
CA B:GLY144 4.3 0.5 1.0
N B:PHE145 4.5 0.2 1.0
N A:GLY253 4.5 0.5 1.0
N B:GLY253 4.5 0.7 1.0
N A:PHE145 4.6 0.2 1.0
N A:GLY144 4.6 0.3 1.0
N B:PHE254 4.6 0.5 1.0
N B:GLY144 4.6 0.6 1.0
N A:PHE254 4.6 0.3 1.0
CA B:PHE145 4.7 0.8 1.0
CA A:PHE145 4.8 0.1 1.0
CA B:PHE254 4.9 0.1 1.0
CA A:PHE254 5.0 0.2 1.0
O B:PHE254 5.0 0.3 1.0
C B:PHE145 5.0 0.4 1.0

Potassium binding site 5 out of 6 in 6v36

Go back to Potassium Binding Sites List in 6v36
Potassium binding site 5 out of 6 in the K2P2.1(Trek-1)I110D Apo Channel Structure


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of K2P2.1(Trek-1)I110D Apo Channel Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K409

b:0.8
occ:0.40
 O A:PHE254 2.7 0.9 1.0
O A:GLY253 2.8 0.7 1.0
O B:PHE254 2.8 0.3 1.0
O B:PHE145 2.8 0.1 1.0
O A:PHE145 2.9 0.2 1.0
O A:GLY144 2.9 0.2 1.0
O B:GLY144 2.9 0.2 1.0
O B:GLY253 2.9 0.3 1.0
K A:K408 2.9 0.8 1.0
C B:PHE145 3.3 0.4 1.0
C A:PHE145 3.4 0.0 1.0
C A:PHE254 3.5 0.4 1.0
C B:PHE254 3.6 0.3 1.0
C A:GLY253 3.9 0.9 1.0
CA A:PHE254 3.9 0.2 1.0
CA A:PHE145 3.9 0.1 1.0
CA B:PHE145 3.9 0.8 1.0
C A:GLY144 4.0 0.2 1.0
C B:GLY144 4.0 0.6 1.0
CA B:PHE254 4.0 0.1 1.0
C B:GLY253 4.1 0.6 1.0
N B:GLY146 4.1 0.2 1.0
N A:GLY146 4.2 0.5 1.0
N A:PHE254 4.4 0.3 1.0
CA B:GLY146 4.4 0.3 1.0
N A:PHE145 4.4 0.2 1.0
N B:PHE145 4.5 0.2 1.0
N A:GLY255 4.5 0.1 1.0
N B:PHE254 4.6 0.5 1.0
N B:GLY255 4.6 0.7 1.0
CA A:GLY146 4.6 0.7 1.0
O A:ILE143 4.9 0.4 1.0
O A:ILE252 5.0 0.9 1.0
CA A:GLY255 5.0 0.7 1.0

Potassium binding site 6 out of 6 in 6v36

Go back to Potassium Binding Sites List in 6v36
Potassium binding site 6 out of 6 in the K2P2.1(Trek-1)I110D Apo Channel Structure


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of K2P2.1(Trek-1)I110D Apo Channel Structure within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K405

b:0.1
occ:1.00
 O B:HOH502 2.9 0.4 1.0
O A:HOH501 3.5 0.9 1.0
OG1 A:THR142 4.4 0.9 1.0
OG1 B:THR251 4.5 0.2 1.0
K A:K406 4.6 0.7 1.0
OG1 A:THR251 4.6 0.9 1.0
CG2 B:THR251 4.8 1.0 1.0
OG1 B:THR142 4.8 0.6 1.0

Reference:

L.Pope, M.Lolicato, D.L.Minor Jr.. Polynuclear Ruthenium Amines Inhibit K2PCHANNELS Via A "Finger in the Dam" Mechanism. Cell Chem Biol 2020.
ISSN: ESSN 2451-9456
PubMed: 32059793
DOI: 10.1016/J.CHEMBIOL.2020.01.011
Page generated: Sat Aug 9 12:22:09 2025

Last articles

Na in 6O6R
Na in 6O93
Na in 6O7S
Na in 6O8G
Na in 6O7C
Na in 6O5E
Na in 6O6A
Na in 6O6J
Na in 6O5X
Na in 6NZY
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy