Potassium in PDB 6ufe: The Structure of A Potassium Selective Ion Channel at Atomic Resolution
Protein crystallography data
The structure of The Structure of A Potassium Selective Ion Channel at Atomic Resolution, PDB code: 6ufe
was solved by
P.S.Langan,
V.G.Vandavasi,
B.Sullivan,
P.V.Afonine,
K.L.Weiss,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
21.46 /
1.20
|
Space group
|
I 4
|
Cell size a, b, c (Å), α, β, γ (°)
|
67.860,
67.860,
89.620,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
13.3 /
14.8
|
Potassium Binding Sites:
The binding sites of Potassium atom in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
(pdb code 6ufe). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 8 binding sites of Potassium where determined in the
The Structure of A Potassium Selective Ion Channel at Atomic Resolution, PDB code: 6ufe:
Jump to Potassium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Potassium binding site 1 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 1 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K705
b:14.4
occ:0.25
|
OG1
|
A:THR63
|
2.8
|
14.1
|
1.0
|
O
|
A:THR63
|
3.0
|
12.7
|
1.0
|
HB
|
A:THR63
|
3.1
|
16.4
|
1.0
|
CB
|
A:THR63
|
3.5
|
13.6
|
1.0
|
K
|
A:K706
|
3.5
|
11.6
|
0.2
|
C
|
A:THR63
|
3.9
|
11.7
|
1.0
|
CA
|
A:THR63
|
4.3
|
12.1
|
1.0
|
HG21
|
A:THR63
|
4.6
|
18.3
|
1.0
|
HA
|
A:VAL64
|
4.7
|
14.1
|
1.0
|
CG2
|
A:THR63
|
4.7
|
15.3
|
1.0
|
HA
|
A:THR63
|
4.8
|
14.5
|
1.0
|
N
|
A:VAL64
|
4.9
|
12.3
|
1.0
|
|
Potassium binding site 2 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 2 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K706
b:11.6
occ:0.25
|
O
|
A:THR63
|
2.6
|
12.7
|
1.0
|
O
|
A:VAL64
|
2.9
|
11.5
|
1.0
|
K
|
A:K707
|
3.2
|
12.2
|
0.2
|
K
|
A:K705
|
3.5
|
14.4
|
0.2
|
HA
|
A:VAL64
|
3.6
|
14.1
|
1.0
|
C
|
A:VAL64
|
3.6
|
11.3
|
1.0
|
C
|
A:THR63
|
3.8
|
11.7
|
1.0
|
CA
|
A:VAL64
|
4.0
|
11.8
|
1.0
|
HA3
|
A:GLY65
|
4.3
|
14.4
|
1.0
|
N
|
A:VAL64
|
4.4
|
12.3
|
1.0
|
HB
|
A:THR63
|
4.5
|
16.4
|
1.0
|
N
|
A:GLY65
|
4.5
|
11.9
|
1.0
|
CA
|
A:GLY65
|
4.8
|
12.0
|
1.0
|
CA
|
A:THR63
|
4.9
|
12.1
|
1.0
|
|
Potassium binding site 3 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 3 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 3 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K707
b:12.2
occ:0.25
|
O
|
A:GLY65
|
2.7
|
11.6
|
1.0
|
O
|
A:VAL64
|
2.9
|
11.5
|
1.0
|
K
|
A:K706
|
3.2
|
11.6
|
0.2
|
C
|
A:GLY65
|
3.4
|
11.4
|
1.0
|
HA3
|
A:GLY65
|
3.5
|
14.4
|
1.0
|
K
|
A:K708
|
3.6
|
14.3
|
0.2
|
CA
|
A:GLY65
|
3.9
|
12.0
|
1.0
|
C
|
A:VAL64
|
4.0
|
11.3
|
1.0
|
HA
|
A:TYR66
|
4.2
|
14.0
|
1.0
|
N
|
A:TYR66
|
4.4
|
11.3
|
1.0
|
N
|
A:GLY65
|
4.4
|
11.9
|
1.0
|
CA
|
A:TYR66
|
4.8
|
11.7
|
1.0
|
HA2
|
A:GLY65
|
4.8
|
14.4
|
1.0
|
|
Potassium binding site 4 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 4 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 4 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K708
b:14.3
occ:0.24
|
O
|
A:TYR66
|
2.7
|
12.3
|
1.0
|
O
|
A:GLY65
|
3.2
|
11.6
|
1.0
|
C
|
A:TYR66
|
3.4
|
11.5
|
1.0
|
K
|
A:K707
|
3.6
|
12.2
|
0.2
|
HA
|
A:TYR66
|
3.6
|
14.0
|
1.0
|
HA3
|
A:GLY67
|
3.8
|
15.7
|
1.0
|
CA
|
A:TYR66
|
4.0
|
11.7
|
1.0
|
N
|
A:GLY67
|
4.2
|
11.9
|
1.0
|
C
|
A:GLY65
|
4.3
|
11.4
|
1.0
|
CA
|
A:GLY67
|
4.5
|
13.0
|
1.0
|
N
|
A:TYR66
|
4.7
|
11.3
|
1.0
|
H
|
A:GLY67
|
4.9
|
14.3
|
1.0
|
|
Potassium binding site 5 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 5 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 5 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:K203
b:14.7
occ:0.25
|
OG1
|
B:THR63
|
2.8
|
13.3
|
1.0
|
O
|
B:THR63
|
3.0
|
12.7
|
1.0
|
HB
|
B:THR63
|
3.1
|
16.0
|
1.0
|
K
|
B:K204
|
3.5
|
13.9
|
0.2
|
CB
|
B:THR63
|
3.5
|
13.3
|
1.0
|
C
|
B:THR63
|
3.9
|
12.5
|
1.0
|
CA
|
B:THR63
|
4.4
|
12.0
|
1.0
|
HG21
|
B:THR63
|
4.7
|
16.5
|
1.0
|
HA
|
B:VAL64
|
4.7
|
14.6
|
1.0
|
CG2
|
B:THR63
|
4.8
|
13.8
|
1.0
|
HA
|
B:THR63
|
4.9
|
14.4
|
1.0
|
N
|
B:VAL64
|
4.9
|
12.2
|
1.0
|
|
Potassium binding site 6 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 6 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 6 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:K204
b:13.9
occ:0.25
|
O
|
B:THR63
|
2.6
|
12.7
|
1.0
|
O
|
B:VAL64
|
2.8
|
12.4
|
1.0
|
K
|
B:K205
|
3.2
|
12.2
|
0.2
|
K
|
B:K203
|
3.5
|
14.7
|
0.2
|
C
|
B:VAL64
|
3.6
|
12.1
|
1.0
|
HA
|
B:VAL64
|
3.6
|
14.6
|
1.0
|
C
|
B:THR63
|
3.8
|
12.5
|
1.0
|
CA
|
B:VAL64
|
4.0
|
12.1
|
1.0
|
HA3
|
B:GLY65
|
4.2
|
15.5
|
1.0
|
N
|
B:VAL64
|
4.4
|
12.2
|
1.0
|
N
|
B:GLY65
|
4.5
|
13.0
|
1.0
|
HB
|
B:THR63
|
4.5
|
16.0
|
1.0
|
CA
|
B:GLY65
|
4.8
|
12.9
|
1.0
|
CA
|
B:THR63
|
4.9
|
12.0
|
1.0
|
|
Potassium binding site 7 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 7 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 7 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:K205
b:12.2
occ:0.22
|
O
|
B:GLY65
|
2.7
|
13.3
|
1.0
|
O
|
B:VAL64
|
2.9
|
12.4
|
1.0
|
K
|
B:K204
|
3.2
|
13.9
|
0.2
|
C
|
B:GLY65
|
3.4
|
12.5
|
1.0
|
HA3
|
B:GLY65
|
3.5
|
15.5
|
1.0
|
K
|
B:K206
|
3.6
|
16.6
|
0.2
|
CA
|
B:GLY65
|
3.9
|
12.9
|
1.0
|
C
|
B:VAL64
|
4.0
|
12.1
|
1.0
|
HA
|
B:TYR66
|
4.3
|
16.4
|
1.0
|
N
|
B:TYR66
|
4.4
|
13.1
|
1.0
|
N
|
B:GLY65
|
4.5
|
13.0
|
1.0
|
CA
|
B:TYR66
|
4.8
|
13.7
|
1.0
|
HA2
|
B:GLY65
|
4.8
|
15.5
|
1.0
|
|
Potassium binding site 8 out
of 8 in 6ufe
Go back to
Potassium Binding Sites List in 6ufe
Potassium binding site 8 out
of 8 in the The Structure of A Potassium Selective Ion Channel at Atomic Resolution
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 8 of The Structure of A Potassium Selective Ion Channel at Atomic Resolution within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:K206
b:16.6
occ:0.25
|
O
|
B:TYR66
|
2.7
|
15.1
|
1.0
|
O
|
B:GLY65
|
3.2
|
13.3
|
1.0
|
C
|
B:TYR66
|
3.4
|
14.0
|
1.0
|
K
|
B:K205
|
3.6
|
12.2
|
0.2
|
HA
|
B:TYR66
|
3.6
|
16.4
|
1.0
|
HA3
|
B:GLY67
|
3.8
|
19.1
|
1.0
|
CA
|
B:TYR66
|
4.0
|
13.7
|
1.0
|
N
|
B:GLY67
|
4.2
|
14.2
|
1.0
|
C
|
B:GLY65
|
4.3
|
12.5
|
1.0
|
CA
|
B:GLY67
|
4.5
|
15.9
|
1.0
|
N
|
B:TYR66
|
4.7
|
13.1
|
1.0
|
H
|
B:GLY67
|
4.8
|
17.0
|
1.0
|
|
Reference:
P.S.Langan,
V.G.Vandavasi,
W.Kopec,
B.Sullivan,
P.V.Afonne,
K.L.Weiss,
B.L.De Groot,
L.Coates.
The Structure of A Potassium-Selective Ion Channel Reveals A Hydrophobic Gate Regulating Ion Permeation. Iucrj V. 7 835 2020.
ISSN: ESSN 2052-2525
PubMed: 32939275
DOI: 10.1107/S2052252520008271
Page generated: Mon Aug 12 17:47:03 2024
|