Potassium in PDB 6isw: Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12

The structure of Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12, PDB code: 6isw was solved by K.Saikrishnan, A.Nuthanakanti, S.G.Srivatsan, I.Ahmad, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.28 / 2.30
Space group	P 21 2 21
Cell size a, b, c (Å), α, β, γ (°)	35.204, 42.280, 49.924, 90.00, 90.00, 90.00
R / Rfree (%)	25.2 / 28.3

The binding sites of Potassium atom in the Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12 (pdb code 6isw). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12, PDB code: 6isw:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12 within 5.0Å range: probe atom residue distance (Å) B Occ A:K101 b:62.7 occ:1.00 O6 A:DG22 2.9 69.5 1.0 O6 A:DG10 2.9 69.0 1.0 O6 A:DG15 2.9 58.4 1.0 O6 A:DG4 2.9 64.5 1.0 O6 A:DG3 2.9 59.5 1.0 O6 A:DG9 2.9 52.5 1.0 O6 A:DG21 2.9 55.8 1.0 O6 A:DG16 2.9 66.9 1.0 K A:K102 3.2 50.5 1.0 C6 A:DG21 3.6 63.0 1.0 C6 A:DG15 3.6 63.7 1.0 C6 A:DG3 3.7 59.7 1.0 C6 A:DG9 3.7 57.7 1.0 N1 A:DG21 3.8 51.6 1.0 N1 A:DG15 3.8 56.3 1.0 C6 A:DG10 3.8 60.5 1.0 C6 A:DG22 3.8 65.1 1.0 C6 A:DG16 3.8 65.0 1.0 C6 A:DG4 3.9 59.3 1.0 N1 A:DG3 3.9 50.3 1.0 N1 A:DG9 4.0 54.1 1.0 N1 A:DG10 4.0 70.3 1.0 N1 A:DG16 4.0 64.6 1.0 N1 A:DG4 4.1 62.4 1.0 N1 A:DG22 4.1 69.1 1.0 C5 A:DG21 4.8 62.0 1.0 C5 A:DG15 4.9 62.1 1.0 C5 A:DG9 4.9 56.5 1.0 C5 A:DG3 4.9 63.2 1.0 C2 A:DG21 4.9 60.1 1.0

Potassium binding site 2 out of 3 in the Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12 within 5.0Å range: probe atom residue distance (Å) B Occ A:K102 b:50.5 occ:1.00 O6 A:DG9 2.8 52.5 1.0 O6 A:DG21 2.8 55.8 1.0 O6 A:DG15 2.9 58.4 1.0 O6 A:DG20 2.9 60.2 1.0 O6 A:DG8 2.9 54.8 1.0 O6 A:DG2 2.9 53.1 1.0 O6 A:DG3 2.9 59.5 1.0 O6 A:DG14 2.9 58.2 1.0 K A:K101 3.2 62.7 1.0 K A:K103 3.3 49.8 0.5 C6 A:DG8 3.7 54.8 1.0 C6 A:DG14 3.7 56.5 1.0 C6 A:DG20 3.7 58.9 1.0 C6 A:DG21 3.7 63.0 1.0 C6 A:DG2 3.8 57.5 1.0 C6 A:DG9 3.8 57.7 1.0 C6 A:DG15 3.8 63.7 1.0 C6 A:DG3 3.8 59.7 1.0 N1 A:DG21 3.9 51.6 1.0 N1 A:DG14 4.0 61.6 1.0 N1 A:DG3 4.0 50.3 1.0 N1 A:DG20 4.0 51.8 1.0 N1 A:DG2 4.0 58.0 1.0 N1 A:DG9 4.1 54.1 1.0 N1 A:DG15 4.1 56.3 1.0 N1 A:DG8 4.1 62.3 1.0 C5 A:DG8 4.9 60.8 1.0 C5 A:DG14 4.9 60.2 1.0 C5 A:DG20 4.9 62.5 1.0 C5 A:DG2 5.0 62.0 1.0

Potassium binding site 3 out of 3 in the Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of Human Telomeric Dna with 5-Selenophene-Modified Deoxyuridine at Residue 12 within 5.0Å range: probe atom residue distance (Å) B Occ A:K103 b:49.8 occ:0.50 O6 A:DG8 2.9 54.8 1.0 O6 A:DG20 2.9 60.2 1.0 O6 A:DG14 2.9 58.2 1.0 O6 A:DG2 2.9 53.1 1.0 K A:K102 3.3 50.5 1.0 C6 A:DG20 3.8 58.9 1.0 C6 A:DG14 3.8 56.5 1.0 C6 A:DG2 3.8 57.5 1.0 C6 A:DG8 3.8 54.8 1.0 N1 A:DG20 4.0 51.8 1.0 N1 A:DG14 4.0 61.6 1.0 N1 A:DG2 4.1 58.0 1.0 N1 A:DG8 4.2 62.3 1.0 C5 A:DG20 5.0 62.5 1.0

A.Nuthanakanti, I.Ahmed, S.Y.Khatik, K.Saikrishnan, S.G.Srivatsan. Probing G-Quadruplex Topologies and Recognition Concurrently in Real Time and 3D Using A Dual-App Nucleoside Probe. Nucleic Acids Res. V. 47 6059 2019.
ISSN: ESSN 1362-4962
PubMed: 31106340
DOI: 10.1093/NAR/GKZ419