Potassium in PDB 6h45: Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine

All present enzymatic activity of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine:
2.4.2.29;

The structure of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine, PDB code: 6h45 was solved by S.Johannsson, P.Neumann, R.Ficner, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.16 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	127.500, 158.860, 47.620, 90.00, 108.19, 90.00
R / Rfree (%)	20.1 / 24

The structure of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine also contains other interesting chemical elements:

Zinc	(Zn)	2 atoms
Bromine	(Br)	4 atoms
Chlorine	(Cl)	5 atoms

The binding sites of Potassium atom in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine (pdb code 6h45). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine, PDB code: 6h45:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine within 5.0Å range: probe atom residue distance (Å) B Occ A:K506 b:53.2 occ:1.00 O A:ARG80 2.6 70.6 1.0 O A:LEU77 2.6 53.8 1.0 O A:GLY82 2.7 56.1 1.0 O A:TYR75 2.7 47.1 1.0 OE2 A:GLU84 3.0 81.4 1.0 CG A:GLU84 3.2 76.0 1.0 CD A:GLU84 3.6 80.6 1.0 C A:TYR75 3.6 50.3 1.0 N A:GLY82 3.6 47.5 1.0 C A:ARG80 3.7 70.6 1.0 C A:GLY82 3.7 52.2 1.0 C A:LEU77 3.8 49.2 1.0 C A:PRO81 3.9 54.5 1.0 CA A:PRO81 3.9 66.0 1.0 O A:THR74 4.1 48.4 1.0 CA A:TYR75 4.2 52.3 1.0 N A:LEU77 4.2 42.4 1.0 CA A:GLY82 4.3 49.8 1.0 N A:PRO81 4.3 71.7 1.0 C A:HIS76 4.5 43.9 1.0 N A:HIS76 4.6 46.6 1.0 O A:PRO81 4.6 52.7 1.0 CA A:LEU77 4.6 42.2 1.0 CB A:GLU84 4.7 68.5 1.0 N A:GLY78 4.7 51.6 1.0 CA A:GLY78 4.7 42.2 1.0 OE1 A:GLU84 4.8 81.8 1.0 N A:ARG80 4.8 67.0 1.0 CA A:HIS76 4.8 46.3 1.0 C A:GLY78 4.9 42.7 1.0 O A:HIS76 4.9 44.9 1.0 N A:PRO83 4.9 55.5 1.0 C A:PRO83 4.9 58.5 1.0 CA A:ARG80 4.9 68.2 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of the Human Tgt Catalytic Subunit QTRT1 in Complex with Queuine within 5.0Å range: probe atom residue distance (Å) B Occ B:K808 b:61.6 occ:1.00 O B:ARG80 2.6 71.5 1.0 O B:LEU77 2.6 64.5 1.0 O B:TYR75 2.6 55.5 1.0 O B:GLY82 2.7 66.7 1.0 OE2 B:GLU84 3.3 77.6 1.0 CG B:GLU84 3.5 75.4 1.0 N B:GLY82 3.5 62.9 1.0 C B:TYR75 3.6 59.0 1.0 C B:ARG80 3.7 71.3 1.0 C B:PRO81 3.7 63.1 1.0 CA B:PRO81 3.8 65.6 1.0 C B:GLY82 3.8 65.2 1.0 C B:LEU77 3.8 60.3 1.0 CD B:GLU84 3.8 76.9 1.0 N B:PRO81 4.2 70.5 1.0 CA B:GLY82 4.3 64.6 1.0 CA B:TYR75 4.3 63.4 1.0 O B:THR74 4.3 61.7 1.0 N B:LEU77 4.3 52.0 1.0 O B:PRO81 4.5 66.7 1.0 C B:HIS76 4.5 51.5 1.0 N B:HIS76 4.6 57.7 1.0 CA B:LEU77 4.7 56.6 1.0 N B:GLY78 4.8 58.8 1.0 CA B:GLY78 4.8 58.1 1.0 CA B:HIS76 4.8 53.8 1.0 C B:GLY78 4.8 60.4 1.0 N B:ARG80 4.9 67.2 1.0 CB B:GLU84 4.9 72.4 1.0 CA B:ARG80 4.9 72.0 1.0 O B:HIS76 4.9 51.8 1.0 N B:PRO83 5.0 65.0 1.0

S.Johannsson, P.Neumann, R.Ficner. Crystal Structure of the Human Trna Guanine Transglycosylase Catalytic Subunit QTRT1. Biomolecules V. 8 2018.
ISSN: ISSN 2218-273X
PubMed: 30149595
DOI: 10.3390/BIOM8030081