Atomistry » Potassium » PDB 5zod-6b7f » 6a7p
Atomistry »
  Potassium »
    PDB 5zod-6b7f »
      6a7p »

Potassium in PDB 6a7p: Human Serum Albumin Complexed with Aripiprazole

Protein crystallography data

The structure of Human Serum Albumin Complexed with Aripiprazole, PDB code: 6a7p was solved by A.Kawai, K.Yamasaki, M.Otagiri, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 48.38 / 2.28
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 59.201, 184.931, 59.269, 90.00, 106.68, 90.00
R / Rfree (%) 20.7 / 25.5

Other elements in 6a7p:

The structure of Human Serum Albumin Complexed with Aripiprazole also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Human Serum Albumin Complexed with Aripiprazole (pdb code 6a7p). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Serum Albumin Complexed with Aripiprazole, PDB code: 6a7p:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 6a7p

Go back to Potassium Binding Sites List in 6a7p
Potassium binding site 1 out of 2 in the Human Serum Albumin Complexed with Aripiprazole


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Serum Albumin Complexed with Aripiprazole within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K603

b:81.2
occ:1.00
O A:HOH745 3.0 42.7 1.0
NH2 A:ARG186 3.0 56.6 1.0
NZ A:LYS519 3.2 53.6 1.0
O A:HOH842 3.3 36.1 1.0
O A:HOH731 3.3 36.6 1.0
NH1 A:ARG186 3.5 54.2 1.0
NZ A:LYS432 3.6 54.9 1.0
CZ A:ARG186 3.7 55.0 1.0
CE A:LYS519 3.9 53.0 1.0
O A:HOH754 4.6 28.9 1.0
NH2 A:ARG428 4.6 42.4 1.0
CD A:LYS190 4.7 46.4 1.0
O A:HOH805 5.0 26.5 1.0
CE A:LYS432 5.0 52.9 1.0

Potassium binding site 2 out of 2 in 6a7p

Go back to Potassium Binding Sites List in 6a7p
Potassium binding site 2 out of 2 in the Human Serum Albumin Complexed with Aripiprazole


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Serum Albumin Complexed with Aripiprazole within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K602

b:55.3
occ:1.00
O B:HOH804 2.8 35.1 1.0
OG B:SER470 2.8 33.4 1.0
O B:HOH702 2.9 47.6 1.0
O B:HOH851 2.9 53.0 1.0
NH1 B:ARG472 2.9 54.5 1.0
CD B:ARG472 3.3 53.0 1.0
N B:ARG472 3.7 43.7 1.0
N B:ASP471 3.7 44.1 1.0
CB B:SER470 3.8 38.9 1.0
CB B:ARG472 3.8 46.0 1.0
CG B:ARG472 3.9 50.0 1.0
CZ B:ARG472 3.9 55.1 1.0
CA B:SER470 4.0 41.3 1.0
NE B:ARG472 4.0 54.4 1.0
O B:HOH843 4.2 29.9 1.0
C B:SER470 4.2 40.5 1.0
CA B:ARG472 4.4 43.3 1.0
CA B:ASP471 4.6 45.8 1.0
C B:ASP471 4.6 43.6 1.0
CB B:ASP471 4.8 49.2 1.0
OD2 B:ASP494 4.9 57.6 1.0

Reference:

K.Sakurama, A.Kawai, V.T.G.Chuang, Y.Kanamori, M.Osa, K.Taguchi, H.Seo, T.Maruyama, S.Imoto, K.Yamasaki, M.Otagiri. Analysis of the Binding of Aripiprazole to Human Serum Albumin: the Importance of A Chloro-Group in the Chemical Structure Acs Omega V. 3 13790 2018.
ISSN: ESSN 2470-1343
DOI: 10.1021/ACSOMEGA.8B02057
Page generated: Mon Aug 12 15:18:23 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy