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Potassium in PDB 5uze: Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182

Enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182

All present enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182:
1.1.1.205;

Protein crystallography data

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182, PDB code: 5uze was solved by N.Maltseva, Y.Kim, R.Mulligan, M.Makowska-Grzyska, M.Gu, D.R.Gollapalli, L.Hedstrom, A.Joachimiak, W.F.Anderson, Center For Structural Genomicsof Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 31.39 / 2.27
Space group P 1
Cell size a, b, c (Å), α, β, γ (°) 64.777, 77.662, 80.321, 110.03, 103.99, 105.46
R / Rfree (%) 19.4 / 25.5

Other elements in 5uze:

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182 also contains other interesting chemical elements:

Fluorine (F) 12 atoms
Chlorine (Cl) 4 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182 (pdb code 5uze). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182, PDB code: 5uze:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 5uze

Go back to Potassium Binding Sites List in 5uze
Potassium binding site 1 out of 2 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K502

b:36.2
occ:1.00
O A:GLU465 2.7 28.1 1.0
O A:SER466 2.7 29.5 1.0
O B:GLY300 2.8 35.2 1.0
O B:CYS303 2.9 22.7 1.0
O B:GLY298 2.9 40.1 1.0
O A:HIS467 3.2 48.8 1.0
C A:SER466 3.3 38.0 1.0
C A:HIS467 3.6 44.2 1.0
C B:CYS303 3.8 43.0 1.0
CA A:SER466 3.8 32.6 1.0
C A:GLU465 3.8 34.3 1.0
CB B:CYS303 3.8 34.5 1.0
C B:GLY300 3.9 38.3 1.0
C B:PRO299 4.0 26.2 1.0
O B:PRO299 4.0 30.1 1.0
C B:GLY298 4.0 34.8 1.0
N A:HIS467 4.1 36.5 1.0
N A:PRO468 4.1 44.2 1.0
CA B:CYS303 4.1 29.9 1.0
N B:GLY300 4.2 32.3 1.0
N B:CYS303 4.2 26.7 1.0
N A:SER466 4.3 34.1 1.0
CD2 A:HIS469 4.3 39.3 1.0
CA A:HIS467 4.3 35.1 1.0
SG B:CYS303 4.3 42.4 1.0
CA B:PRO299 4.4 33.3 1.0
CA A:PRO468 4.5 39.3 1.0
NE2 A:HIS469 4.5 38.5 1.0
CA B:GLY300 4.7 32.0 1.0
N B:PRO299 4.7 31.2 1.0
N B:THR304 4.9 34.5 1.0
N B:SER301 4.9 32.5 1.0
CD A:PRO468 5.0 38.9 1.0
CA B:GLY298 5.0 35.0 1.0

Potassium binding site 2 out of 2 in 5uze

Go back to Potassium Binding Sites List in 5uze
Potassium binding site 2 out of 2 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K503

b:46.5
occ:1.00
O B:GLU465 2.7 30.9 1.0
O D:GLY300 2.7 44.1 1.0
O D:GLY298 2.8 46.4 1.0
O B:SER466 2.8 51.0 1.0
O D:CYS303 2.8 32.6 1.0
O B:HIS467 3.1 47.0 1.0
O D:HOH618 3.1 32.4 1.0
C B:SER466 3.3 43.8 1.0
C B:HIS467 3.5 39.1 1.0
C D:CYS303 3.8 40.9 1.0
C B:GLU465 3.8 38.7 1.0
C D:GLY300 3.9 45.5 1.0
CB D:CYS303 4.0 42.9 1.0
CA B:SER466 4.0 40.3 1.0
C D:GLY298 4.0 41.8 1.0
C D:PRO299 4.0 47.0 1.0
N B:PRO468 4.1 47.0 1.0
N B:HIS467 4.1 37.1 1.0
N D:GLY300 4.1 41.2 1.0
O D:PRO299 4.2 54.4 1.0
SG D:CYS303 4.2 53.4 1.0
CA D:CYS303 4.2 44.5 1.0
CA B:HIS467 4.3 36.7 1.0
N D:CYS303 4.3 41.9 1.0
CD2 B:HIS469 4.3 45.3 1.0
N B:SER466 4.4 33.6 1.0
CA B:PRO468 4.4 51.2 1.0
CA D:PRO299 4.5 39.4 1.0
NE2 B:HIS469 4.5 46.5 1.0
CA D:GLY300 4.6 38.2 1.0
N D:PRO299 4.7 41.0 1.0
CD B:PRO468 4.8 44.0 1.0
N D:SER301 4.9 50.4 1.0
CA D:GLY298 4.9 37.9 1.0
N D:THR304 4.9 41.1 1.0

Reference:

N.Maltseva, Y.Kim, R.Mulligan, M.Makowska-Grzyska, M.Gu, D.R.Gollapalli, L.Hedstrom, A.Joachimiak, W.F.Anderson, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P182 To Be Published.
Page generated: Mon Aug 12 14:48:20 2024

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