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Potassium in PDB 5uxe: Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178

Enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178

All present enzymatic activity of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178:
1.1.1.205;

Protein crystallography data

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178, PDB code: 5uxe was solved by N.Maltseva, Y.Kim, R.Mulligan, M.Makowska-Grzyska, M.Gu, D.R.Gollapalli, L.Hedstrom, A.Joachimiak, W.F.Anderson, Center For Structural Genomicsof Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 39.25 / 2.10
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 127.937, 119.101, 96.971, 90.00, 102.86, 90.00
R / Rfree (%) 17.3 / 22.3

Other elements in 5uxe:

The structure of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 also contains other interesting chemical elements:

Chlorine (Cl) 4 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 (pdb code 5uxe). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178, PDB code: 5uxe:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in 5uxe

Go back to Potassium Binding Sites List in 5uxe
Potassium binding site 1 out of 3 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K502

b:78.2
occ:1.00
O A:GLY300 2.7 36.9 1.0
O A:GLY298 2.8 33.4 1.0
O C:GLU465 2.8 32.6 1.0
O A:CYS303 2.9 24.8 1.0
O C:SER466 3.0 27.6 1.0
O C:HIS467 3.2 35.7 1.0
CB A:CYS303 3.5 37.9 1.0
C C:SER466 3.6 30.2 1.0
C A:CYS303 3.6 28.4 1.0
C C:HIS467 3.7 33.5 1.0
C A:PRO299 3.8 32.6 1.0
C A:GLY300 3.8 31.8 1.0
C A:GLY298 3.8 34.2 1.0
CA A:CYS303 3.9 33.9 1.0
N A:GLY300 3.9 29.9 1.0
C C:GLU465 4.0 33.5 1.0
O A:PRO299 4.0 31.3 1.0
N A:CYS303 4.0 31.8 1.0
CA C:SER466 4.1 33.2 1.0
SG A:CYS303 4.1 41.6 1.0
N C:PRO468 4.2 33.8 1.0
CA A:PRO299 4.2 33.6 1.0
N C:HIS467 4.3 27.7 1.0
CA A:GLY300 4.5 31.8 1.0
N A:PRO299 4.5 31.2 1.0
CA C:HIS467 4.5 30.3 1.0
CD2 C:HIS469 4.5 31.1 1.0
CA C:PRO468 4.5 33.3 1.0
N C:SER466 4.5 31.0 1.0
NE2 C:HIS469 4.6 31.3 1.0
N A:THR304 4.7 29.1 1.0
CA A:GLY298 4.8 35.9 1.0
N A:SER301 4.9 25.4 1.0
C A:SER301 5.0 26.6 1.0
O A:SER301 5.0 29.1 1.0

Potassium binding site 2 out of 3 in 5uxe

Go back to Potassium Binding Sites List in 5uxe
Potassium binding site 2 out of 3 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K504

b:67.0
occ:1.00
O D:GLY300 2.7 25.8 1.0
O D:CYS303 2.8 22.2 1.0
O B:GLU465 2.8 23.8 1.0
O D:GLY298 2.8 28.5 1.0
O B:SER466 2.9 24.9 1.0
O B:HIS467 3.3 29.4 1.0
O B:HOH630 3.4 26.2 1.0
C B:SER466 3.5 27.2 1.0
C B:HIS467 3.6 31.7 1.0
C D:CYS303 3.7 27.0 1.0
CB D:CYS303 3.8 31.3 1.0
C D:GLY300 3.8 29.9 1.0
C D:GLY298 4.0 26.0 1.0
C B:GLU465 4.0 25.1 1.0
C D:PRO299 4.0 29.9 1.0
N D:GLY300 4.0 28.6 1.0
N B:PRO468 4.0 29.2 1.0
CA B:SER466 4.1 26.4 1.0
CA D:CYS303 4.1 30.4 1.0
N D:CYS303 4.1 30.4 1.0
N B:HIS467 4.2 37.3 1.0
O D:PRO299 4.2 27.8 1.0
SG D:CYS303 4.3 34.8 1.0
CA B:PRO468 4.3 29.4 1.0
CD2 B:HIS469 4.3 32.2 1.0
CA B:HIS467 4.4 33.9 1.0
CA D:PRO299 4.4 28.1 1.0
N B:SER466 4.5 23.3 1.0
CA D:GLY300 4.5 28.7 1.0
NE2 B:HIS469 4.6 29.8 1.0
N D:PRO299 4.6 26.4 1.0
N D:THR304 4.8 22.9 1.0
N D:SER301 4.9 23.8 1.0
CD B:PRO468 4.9 23.9 1.0
CA D:GLY298 4.9 26.8 1.0
C D:SER301 4.9 22.0 1.0
O D:SER301 5.0 26.4 1.0

Potassium binding site 3 out of 3 in 5uxe

Go back to Potassium Binding Sites List in 5uxe
Potassium binding site 3 out of 3 in the Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:K501

b:54.4
occ:1.00
O D:GLU465 2.8 32.0 1.0
O C:GLY300 2.8 23.9 1.0
O C:GLY298 2.8 26.9 1.0
O C:CYS303 2.9 22.8 1.0
O D:SER466 3.0 25.8 1.0
O D:HIS467 3.2 29.7 1.0
O D:HOH610 3.3 27.4 1.0
C D:SER466 3.5 25.4 1.0
C D:HIS467 3.6 32.4 1.0
C C:CYS303 3.7 28.4 1.0
CB C:CYS303 3.8 28.9 1.0
C C:GLY300 3.9 26.2 1.0
C C:PRO299 3.9 30.3 1.0
C D:GLU465 3.9 30.0 1.0
C C:GLY298 3.9 25.5 1.0
O C:PRO299 3.9 26.3 1.0
CA D:SER466 4.0 30.8 1.0
CA C:CYS303 4.1 29.2 1.0
N C:GLY300 4.1 30.1 1.0
N D:PRO468 4.1 31.2 1.0
N C:CYS303 4.1 27.6 1.0
SG C:CYS303 4.2 36.3 1.0
CD2 D:HIS469 4.2 28.6 1.0
N D:HIS467 4.2 26.5 1.0
NE2 D:HIS469 4.2 29.1 1.0
CA C:PRO299 4.4 27.4 1.0
CA D:HIS467 4.4 30.9 1.0
CA D:PRO468 4.4 31.2 1.0
N D:SER466 4.4 31.7 1.0
CA C:GLY300 4.6 26.3 1.0
N C:PRO299 4.6 25.4 1.0
N C:THR304 4.8 26.2 1.0
N C:SER301 4.9 26.0 1.0
C C:SER301 4.9 24.9 1.0
CA C:GLY298 5.0 26.6 1.0
CD D:PRO468 5.0 30.4 1.0

Reference:

N.Maltseva, Y.Kim, R.Mulligan, M.Makowska-Grzyska, M.Gu, D.R.Gollapalli, L.Hedstrom, A.Joachimiak, W.F.Anderson, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Inosine 5'-Monophosphate Dehydrogenase From Clostridium Perfringens Complexed with Imp and P178 To Be Published.
Page generated: Mon Aug 12 14:46:05 2024

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