Potassium in PDB 5jzx: Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis

All present enzymatic activity of Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis:
1.3.1.98;

The structure of Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis, PDB code: 5jzx was solved by S.Dharavath, K.Eniyan, U.Bajpai, S.Gourinath, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	38.43 / 2.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	274.924, 79.966, 138.996, 90.00, 112.44, 90.00
R / Rfree (%)	20.7 / 25.9

The binding sites of Potassium atom in the Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis (pdb code 5jzx). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis, PDB code: 5jzx:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ A:K402 b:88.8 occ:1.00 O A:VAL255 2.8 31.2 1.0 O A:SER257 3.0 33.3 1.0 OD1 A:ASN71 3.3 32.6 1.0 OE2 A:GLU361 3.4 45.8 1.0 O A:HOH593 3.6 32.9 1.0 C1' A:FAD401 3.6 24.9 1.0 C A:VAL255 3.9 28.9 1.0 N10 A:FAD401 3.9 26.5 1.0 CG A:GLU361 3.9 47.2 1.0 CB A:GLU361 4.0 42.8 1.0 CD A:GLU361 4.0 49.9 1.0 C A:SER257 4.1 30.7 1.0 N A:SER257 4.2 29.3 1.0 C A:GLY256 4.3 29.7 1.0 C10 A:FAD401 4.3 23.0 1.0 CA A:GLY256 4.3 25.8 1.0 CG A:ASN71 4.4 32.7 1.0 CD A:PRO362 4.4 36.6 1.0 N A:PRO362 4.4 32.9 1.0 N1 A:FAD401 4.4 23.2 1.0 CG A:PRO362 4.4 37.4 1.0 O A:HOH549 4.5 42.4 1.0 N A:GLY256 4.5 25.6 1.0 C9A A:FAD401 4.5 24.3 1.0 C A:GLU361 4.6 35.4 1.0 CA A:SER257 4.6 27.8 1.0 CB A:PRO362 4.7 37.9 1.0 CA A:PRO362 4.8 33.0 1.0 O A:GLY256 4.9 37.2 1.0 C9 A:FAD401 4.9 25.0 1.0 ND2 A:ASN71 4.9 33.2 1.0 O A:GLU361 5.0 37.7 1.0 CA A:GLU361 5.0 36.7 1.0

Potassium binding site 2 out of 3 in the Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ B:K402 b:81.2 occ:1.00 O3' B:FAD401 3.3 36.3 1.0 O2 B:FAD401 3.4 35.8 1.0 CB B:GLN137 3.5 37.2 1.0 N1 B:FAD401 3.9 38.6 1.0 C2 B:FAD401 4.1 38.0 1.0 ND2 B:ASN71 4.1 35.4 1.0 O B:HOH510 4.3 36.8 1.0 CG2 B:VAL139 4.3 34.3 1.0 CD B:ARG176 4.4 61.1 1.0 C3' B:FAD401 4.4 34.7 1.0 CG B:ASN71 4.6 35.4 1.0 C1' B:FAD401 4.6 35.6 1.0 O B:GLN137 4.6 31.2 1.0 OD1 B:ASN71 4.6 34.4 1.0 CA B:GLN137 4.8 35.8 1.0 CB B:GLU361 4.9 36.8 1.0 C B:GLN137 5.0 32.8 1.0 C10 B:FAD401 5.0 36.4 1.0

Potassium binding site 3 out of 3 in the Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of Udp-N-Acetylenolpyruvoylglucosamine Reductase (Murb) From Mycobacterium Tuberculosis within 5.0Å range: probe atom residue distance (Å) B Occ C:K402 b:79.2 occ:1.00 O C:SER257 2.6 24.8 1.0 OE1 C:GLU361 2.7 42.1 1.0 O C:VAL255 2.7 28.6 1.0 O C:HOH567 2.8 27.9 1.0 CD C:GLU361 3.4 39.9 1.0 C C:SER257 3.6 24.0 1.0 CG C:GLU361 3.7 36.5 1.0 N C:SER257 3.7 29.5 1.0 C1' C:FAD401 3.7 24.2 1.0 CB C:GLU361 3.8 28.4 1.0 C C:VAL255 3.9 28.0 1.0 OD1 C:ASN71 3.9 35.9 1.0 C C:GLY256 3.9 31.7 1.0 N10 C:FAD401 3.9 25.6 1.0 CA C:SER257 4.1 26.4 1.0 CA C:GLY256 4.1 29.5 1.0 OE2 C:GLU361 4.3 49.6 1.0 C10 C:FAD401 4.3 23.0 1.0 CB C:SER257 4.4 28.3 1.0 N C:GLY256 4.4 26.3 1.0 N1 C:FAD401 4.4 24.7 1.0 C9A C:FAD401 4.5 25.7 1.0 O C:GLY256 4.6 31.6 1.0 N C:PHE258 4.7 24.0 1.0 NH1 C:ARG176 4.9 64.8 1.0 C9 C:FAD401 4.9 26.0 1.0 CD C:PRO362 4.9 32.1 1.0 NE2 C:GLN137 4.9 38.1 1.0 CG C:ASN71 5.0 27.0 1.0

K.Eniyan, S.Dharavath, R.Vijayan, U.Bajpai, S.Gourinath. Crystal Structure of Udp-N-Acetylglucosamine-Enolpyruvate Reductase (Murb) From Mycobacterium Tuberculosis Biochim. Biophys. Acta V.1866 397 2017.
ISSN: ISSN 0006-3002
PubMed: 29203374
DOI: 10.1016/J.BBAPAP.2017.11.013