Potassium in PDB 5cbt: Human Cyclophilin D Complexed with Inhibitor

All present enzymatic activity of Human Cyclophilin D Complexed with Inhibitor:
5.2.1.8;

The structure of Human Cyclophilin D Complexed with Inhibitor, PDB code: 5cbt was solved by R.P.Gibson, E.Shore, N.Kershaw, M.Awais, A.Javed, D.Latawiec, S.Pandalaneni, L.Wen, N.Berry, P.O'neill, R.Sutton, L.Y.Lian, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.91 / 1.45
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	57.849, 57.849, 114.455, 90.00, 90.00, 90.00
R / Rfree (%)	17.7 / 19.9

The binding sites of Potassium atom in the Human Cyclophilin D Complexed with Inhibitor (pdb code 5cbt). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Human Cyclophilin D Complexed with Inhibitor, PDB code: 5cbt:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Human Cyclophilin D Complexed with Inhibitor


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human Cyclophilin D Complexed with Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:K202 b:20.5 occ:0.50 O2 A:PGE207 2.6 30.8 1.0 O3 A:PGE207 2.8 29.2 1.0 O1 A:PGE207 3.0 26.3 1.0 O A:HOH389 3.0 32.6 0.5 O4 A:PGE207 3.0 38.2 1.0 C1 A:PGE207 3.5 29.9 1.0 C2 A:PGE207 3.6 30.0 1.0 C3 A:PGE207 3.6 28.1 1.0 C4 A:PGE207 3.7 32.5 1.0 C6 A:PGE207 3.8 34.7 1.0 C5 A:PGE207 3.8 34.5 1.0 O A:HOH410 4.7 34.5 1.0

Potassium binding site 2 out of 2 in the Human Cyclophilin D Complexed with Inhibitor


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human Cyclophilin D Complexed with Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:K203 b:32.5 occ:1.00 O A:CYS161 2.7 15.7 1.0 O A:HOH316 2.7 33.8 1.0 O1 A:FMT204 2.9 43.9 1.0 OD1 A:ASP160 2.9 21.5 1.0 OH A:TYR7 3.3 23.9 1.0 CG A:ASP160 3.8 22.8 1.0 C A:CYS161 3.8 12.7 1.0 C A:FMT204 3.8 24.3 1.0 O A:HOH315 3.9 27.5 1.0 OD2 A:ASP160 4.0 30.7 1.0 CZ A:TYR7 4.4 16.9 1.0 N A:CYS161 4.4 14.2 1.0 CA A:GLY162 4.5 13.1 1.0 NZ A:LYS49 4.6 36.5 1.0 N A:GLY162 4.6 12.3 1.0 O A:HOH401 4.7 19.7 1.0 CA A:CYS161 4.8 14.5 1.0 O2 A:FMT204 4.9 29.1 1.0

R.P.Gibson, E.Shore, N.Kershaw, M.Awais, A.Javed, D.Latawiec, S.Pandalaneni, L.Wen, N.Berry, P.O'neill, R.Sutton, L.Y.Lian. Human Cyclophilin D Complexed with Inhibitor To Be Published.