Potassium in PDB 4xk0: Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
Protein crystallography data
The structure of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium, PDB code: 4xk0
was solved by
M.C.Chen,
P.Murat,
K.A.Abecassis,
A.R.Ferre-D'amare,
S.Balasubramanian,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
21.54 /
1.08
|
Space group
|
P 4
|
Cell size a, b, c (Å), α, β, γ (°)
|
33.133,
33.133,
54.843,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
n/a /
n/a
|
Other elements in 4xk0:
The structure of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium also contains other interesting chemical elements:
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
(pdb code 4xk0). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 9 binding sites of Potassium where determined in the
Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium, PDB code: 4xk0:
Jump to Potassium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
9;
Potassium binding site 1 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 1 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K101
b:4.2
occ:0.26
|
O6
|
A:G1
|
2.7
|
3.9
|
1.0
|
O6
|
C:G-2
|
3.1
|
3.9
|
1.0
|
K
|
A:K105
|
3.1
|
5.3
|
0.0
|
H1
|
A:G1
|
3.4
|
4.9
|
1.0
|
K
|
C:K101
|
3.5
|
4.0
|
0.3
|
H1
|
C:G-2
|
3.7
|
5.2
|
1.0
|
C6
|
A:G1
|
3.7
|
4.6
|
1.0
|
C6
|
C:G-2
|
3.8
|
4.5
|
1.0
|
N1
|
A:G1
|
3.9
|
4.0
|
1.0
|
N1
|
C:G-2
|
4.0
|
4.3
|
1.0
|
C5
|
C:G-2
|
5.0
|
4.3
|
1.0
|
|
Potassium binding site 2 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 2 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K102
b:4.2
occ:0.26
|
O6
|
A:G2
|
2.7
|
4.5
|
1.0
|
O6
|
A:G3
|
3.0
|
4.2
|
1.0
|
H1
|
A:G2
|
3.4
|
5.0
|
1.0
|
K
|
A:K103
|
3.4
|
4.2
|
0.3
|
K
|
A:K105
|
3.5
|
5.3
|
0.0
|
C6
|
A:G2
|
3.6
|
4.5
|
1.0
|
H1
|
A:G3
|
3.8
|
5.3
|
1.0
|
C6
|
A:G3
|
3.8
|
4.6
|
1.0
|
N1
|
A:G2
|
3.9
|
4.1
|
1.0
|
N1
|
A:G3
|
4.1
|
4.4
|
1.0
|
C5
|
A:G2
|
4.9
|
4.4
|
1.0
|
C5
|
A:G3
|
4.9
|
4.6
|
1.0
|
|
Potassium binding site 3 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 3 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 3 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K103
b:4.2
occ:0.27
|
O6
|
A:G3
|
2.7
|
4.2
|
1.0
|
O6
|
A:G4
|
2.8
|
4.3
|
1.0
|
K
|
A:K104
|
3.3
|
4.3
|
0.2
|
K
|
A:K102
|
3.4
|
4.2
|
0.3
|
H1
|
A:G3
|
3.5
|
5.3
|
1.0
|
C6
|
A:G3
|
3.6
|
4.6
|
1.0
|
H1
|
A:G4
|
3.6
|
5.4
|
1.0
|
C6
|
A:G4
|
3.7
|
4.9
|
1.0
|
N1
|
A:G3
|
3.9
|
4.4
|
1.0
|
N1
|
A:G4
|
4.0
|
4.5
|
1.0
|
C5
|
A:G3
|
4.8
|
4.6
|
1.0
|
C5
|
A:G4
|
5.0
|
4.9
|
1.0
|
|
Potassium binding site 4 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 4 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 4 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K104
b:4.3
occ:0.24
|
O4
|
A:U5
|
2.7
|
5.2
|
1.0
|
O6
|
A:G4
|
2.9
|
4.3
|
1.0
|
K
|
A:K103
|
3.3
|
4.2
|
0.3
|
H3
|
A:U5
|
3.3
|
6.8
|
1.0
|
H1
|
A:G4
|
3.6
|
5.4
|
1.0
|
C6
|
A:G4
|
3.7
|
4.9
|
1.0
|
C4
|
A:U5
|
3.7
|
5.8
|
1.0
|
N3
|
A:U5
|
3.9
|
5.7
|
1.0
|
N1
|
A:G4
|
3.9
|
4.5
|
1.0
|
C5
|
A:G4
|
4.8
|
4.9
|
1.0
|
|
Potassium binding site 5 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 5 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 5 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K105
b:5.3
occ:0.04
|
K
|
A:K101
|
3.1
|
4.2
|
0.3
|
O6
|
A:G1
|
3.1
|
3.9
|
1.0
|
O6
|
A:G2
|
3.3
|
4.5
|
1.0
|
K
|
A:K102
|
3.5
|
4.2
|
0.3
|
H1
|
A:G1
|
3.6
|
4.9
|
1.0
|
C6
|
A:G1
|
3.8
|
4.6
|
1.0
|
H1
|
A:G2
|
3.8
|
5.0
|
1.0
|
N1
|
A:G1
|
4.0
|
4.0
|
1.0
|
C6
|
A:G2
|
4.0
|
4.5
|
1.0
|
N1
|
A:G2
|
4.2
|
4.1
|
1.0
|
C5
|
A:G1
|
4.9
|
4.5
|
1.0
|
|
Potassium binding site 6 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 6 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 6 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K101
b:4.0
occ:0.26
|
O6
|
C:G-2
|
2.7
|
3.9
|
1.0
|
O6
|
C:G-1
|
3.0
|
3.7
|
1.0
|
K
|
C:K102
|
3.3
|
4.0
|
0.2
|
K
|
A:K101
|
3.5
|
4.2
|
0.3
|
H1
|
C:G-2
|
3.5
|
5.2
|
1.0
|
H1
|
C:G-1
|
3.7
|
4.9
|
1.0
|
C6
|
C:G-2
|
3.7
|
4.5
|
1.0
|
C6
|
C:G-1
|
3.7
|
4.4
|
1.0
|
N1
|
C:G-2
|
4.0
|
4.3
|
1.0
|
N1
|
C:G-1
|
4.0
|
4.1
|
1.0
|
C5
|
C:G-1
|
4.9
|
4.2
|
1.0
|
C5
|
C:G-2
|
4.9
|
4.3
|
1.0
|
|
Potassium binding site 7 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 7 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 7 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K102
b:4.0
occ:0.25
|
O6
|
C:G-1
|
2.7
|
3.7
|
1.0
|
O6
|
C:G0
|
2.9
|
3.6
|
1.0
|
K
|
C:K103
|
3.3
|
4.0
|
0.3
|
K
|
C:K101
|
3.3
|
4.0
|
0.3
|
H1
|
C:G-1
|
3.5
|
4.9
|
1.0
|
C6
|
C:G-1
|
3.6
|
4.4
|
1.0
|
H1
|
C:G0
|
3.7
|
4.8
|
1.0
|
C6
|
C:G0
|
3.7
|
4.5
|
1.0
|
N1
|
C:G-1
|
4.0
|
4.1
|
1.0
|
N1
|
C:G0
|
4.0
|
4.0
|
1.0
|
C5
|
C:G0
|
4.9
|
4.2
|
1.0
|
C5
|
C:G-1
|
4.9
|
4.2
|
1.0
|
|
Potassium binding site 8 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 8 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 8 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K103
b:4.0
occ:0.27
|
O6
|
C:G0
|
2.7
|
3.6
|
1.0
|
O6
|
C:G1
|
2.7
|
3.8
|
1.0
|
K
|
C:K102
|
3.3
|
4.0
|
0.2
|
K
|
C:K104
|
3.4
|
4.0
|
0.2
|
H1
|
C:G0
|
3.5
|
4.8
|
1.0
|
H1
|
C:G1
|
3.6
|
4.9
|
1.0
|
C6
|
C:G0
|
3.6
|
4.5
|
1.0
|
C6
|
C:G1
|
3.7
|
4.4
|
1.0
|
N1
|
C:G0
|
3.9
|
4.0
|
1.0
|
N1
|
C:G1
|
4.0
|
4.1
|
1.0
|
C5
|
C:G0
|
4.9
|
4.2
|
1.0
|
C5
|
C:G1
|
5.0
|
4.8
|
1.0
|
|
Potassium binding site 9 out
of 9 in 4xk0
Go back to
Potassium Binding Sites List in 4xk0
Potassium binding site 9 out
of 9 in the Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium
 Mono view
 Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 9 of Crystal Structure of A Tetramolecular Rna G-Quadruplex in Potassium within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:K104
b:4.0
occ:0.24
|
O4
|
C:U2
|
2.7
|
5.6
|
1.0
|
O6
|
C:G1
|
3.0
|
3.8
|
1.0
|
H3
|
C:U2
|
3.3
|
7.1
|
1.0
|
K
|
C:K103
|
3.4
|
4.0
|
0.3
|
H1
|
C:G1
|
3.6
|
4.9
|
1.0
|
C4
|
C:U2
|
3.7
|
5.6
|
1.0
|
C6
|
C:G1
|
3.7
|
4.4
|
1.0
|
N3
|
C:U2
|
3.9
|
5.9
|
1.0
|
N1
|
C:G1
|
4.0
|
4.1
|
1.0
|
C5
|
C:G1
|
4.9
|
4.8
|
1.0
|
|
Reference:
M.C.Chen,
P.Murat,
K.A.Abecassis,
A.R.Ferre-D'amare,
S.Balasubramanian.
Insights Into the Mechanism of A G-Quadruplex-Unwinding Deah-Box Helicase Nucleic Acids Res. 2015.
ISSN: ESSN 1362-4962
DOI: 10.1093/NAR/GKV051
Page generated: Mon Aug 12 12:35:52 2024
|