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Potassium in PDB 4qcl: Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp

Enzymatic activity of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp

All present enzymatic activity of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp:
2.7.7.7;

Protein crystallography data

The structure of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp, PDB code: 4qcl was solved by A.G.Baranovskiy, Y.Suwa, N.D.Babayeva, J.Gu, T.H.Tahirov, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 29.51 / 2.20
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 140.763, 140.763, 181.315, 90.00, 90.00, 120.00
R / Rfree (%) 21 / 23.9

Other elements in 4qcl:

The structure of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp also contains other interesting chemical elements:

Magnesium (Mg) 1 atom
Zinc (Zn) 3 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp (pdb code 4qcl). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp, PDB code: 4qcl:

Potassium binding site 1 out of 1 in 4qcl

Go back to Potassium Binding Sites List in 4qcl
Potassium binding site 1 out of 1 in the Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Catalytic Core of Human Dna Polymerase Alpha in Ternary Complex with An Rna-Primed Dna Template and Dctp within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K1305

b:54.4
occ:1.00
 O A:ILE1227 2.6 56.6 1.0
O A:HOH1510 2.8 41.3 1.0
O A:ILE1230 2.8 53.5 1.0
O A:CYS1224 3.0 40.6 1.0
O A:GLU1225 3.0 50.0 1.0
C A:GLU1225 3.6 46.2 1.0
C A:ILE1227 3.6 56.1 1.0
C A:ILE1230 3.9 42.9 1.0
N A:ILE1227 3.9 43.8 1.0
C A:CYS1224 4.0 40.9 1.0
CA A:GLU1225 4.1 42.4 1.0
C A:PRO1226 4.3 46.9 1.0
CA A:ILE1227 4.3 45.8 1.0
N A:PRO1226 4.3 56.7 1.0
N A:GLU1225 4.5 39.8 1.0
N A:ASP1228 4.5 61.7 1.0
CA A:ASP1231 4.6 38.0 1.0
CA A:PRO1226 4.6 50.8 1.0
N A:ASP1231 4.6 44.5 1.0
N A:ILE1230 4.7 54.7 1.0
CA A:ILE1230 4.7 40.9 1.0
CA A:ASP1228 4.7 63.2 1.0
CB A:ILE1230 4.8 50.6 1.0
O A:HOH1742 4.9 48.0 1.0
O A:PRO1226 4.9 59.0 1.0
CB A:ILE1227 5.0 44.9 1.0

Reference:

A.G.Baranovskiy, N.D.Babayeva, Y.Suwa, J.Gu, T.H.Tahirov. Crystal Structure of Human Dna Polymerase Alpha Catalytic Core in Complex with Dna/Rna and Dcp To Be Published.
Page generated: Sat Aug 9 07:42:10 2025

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