Potassium in PDB 4q0o: Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand

The structure of Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand, PDB code: 4q0o was solved by P.Filippakopoulos, S.Picaud, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, C.Bountra, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.60 / 1.83
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	59.210, 139.350, 41.710, 90.00, 90.00, 90.00
R / Rfree (%)	19.7 / 22.4

The binding sites of Potassium atom in the Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand (pdb code 4q0o). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand, PDB code: 4q0o:

Potassium binding site 1 out of 1 in the Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand within 5.0Å range: probe atom residue distance (Å) B Occ A:K801 b:40.0 occ:1.00 O A:ASN707 2.8 29.9 1.0 O A:HOH945 2.8 50.6 1.0 O A:CYS704 2.8 36.4 1.0 O A:THR705 2.9 27.2 1.0 O A:HOH968 3.3 47.2 1.0 C A:THR705 3.5 24.8 1.0 C A:ASN707 3.7 25.5 1.0 O A:HOH944 3.9 47.1 1.0 C A:CYS704 3.9 30.1 1.0 CA A:THR705 3.9 29.9 1.0 CD A:PRO709 4.2 41.3 1.0 CA A:GLU708 4.4 41.2 1.0 N A:ASN707 4.4 26.4 1.0 N A:THR705 4.4 30.0 1.0 N A:GLU708 4.4 31.9 1.0 O A:HOH979 4.5 59.7 1.0 N A:TYR706 4.5 24.9 1.0 C A:TYR706 4.5 24.7 1.0 CE1 A:TYR714 4.6 31.8 1.0 CA A:ASN707 4.8 23.4 1.0 N A:PRO709 4.8 42.7 1.0 O A:TYR706 4.8 26.7 1.0 CD1 A:TYR714 4.8 31.8 1.0 C A:GLU708 4.9 33.1 1.0 OE1 A:GLU708 4.9 49.9 1.0

P.Filippakopoulos, S.Picaud, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, C.Bountra, S.Knapp, Structural Genomics Consortium (Sgc). Crystal Structure of the Fifth Bromodomain of Human Poly-Bromodomain Containing Protein 1 (PB1) in Complex with A Hydroxyphenyl-Propenone Ligand To Be Published.