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Atomistry » Potassium » PDB 3oyt-3q9b » 3pp7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Potassium » PDB 3oyt-3q9b » 3pp7 » |
Potassium in PDB 3pp7: Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.Enzymatic activity of Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.
All present enzymatic activity of Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.:
2.7.1.40; Protein crystallography data
The structure of Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis., PDB code: 3pp7
was solved by
H.P.Morgan,
D.S.Auld,
I.W.Mcnae,
M.W.Nowicki,
P.A.M.Michels,
L.A.Fothergill-Gilmore,
M.D.Walkinshaw,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.
(pdb code 3pp7). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis., PDB code: 3pp7: Jump to Potassium binding site number: 1; 2; 3; 4; Potassium binding site 1 out of 4 in 3pp7Go back to![]() ![]()
Potassium binding site 1 out
of 4 in the Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.
![]() Mono view ![]() Stereo pair view
Potassium binding site 2 out of 4 in 3pp7Go back to![]() ![]()
Potassium binding site 2 out
of 4 in the Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.
![]() Mono view ![]() Stereo pair view
Potassium binding site 3 out of 4 in 3pp7Go back to![]() ![]()
Potassium binding site 3 out
of 4 in the Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.
![]() Mono view ![]() Stereo pair view
Potassium binding site 4 out of 4 in 3pp7Go back to![]() ![]()
Potassium binding site 4 out
of 4 in the Crystal Structure of Leishmania Mexicana Pyruvate Kinase in Complex with the Drug Suramin, An Inhibitor of Glycolysis.
![]() Mono view ![]() Stereo pair view
Reference:
H.P.Morgan,
I.W.Mcnae,
M.W.Nowicki,
W.Zhong,
P.A.Michels,
D.S.Auld,
L.A.Fothergill-Gilmore,
M.D.Walkinshaw.
The Trypanocidal Drug Suramin and Other Trypan Blue Mimetics Are Inhibitors of Pyruvate Kinases and Bind to the Adenosine Site. J.Biol.Chem. V. 286 31232 2011.
Page generated: Mon Aug 12 09:03:38 2024
ISSN: ISSN 0021-9258 PubMed: 21733839 DOI: 10.1074/JBC.M110.212613 |
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