Potassium in PDB 3i55: Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit

The structure of Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit, PDB code: 3i55 was solved by G.Gurel, G.Blaha, T.A.Steitz, P.B.Moore, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.98 / 3.11
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	211.324, 299.649, 574.241, 90.00, 90.00, 90.00
R / Rfree (%)	21 / 26

The structure of Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit also contains other interesting chemical elements:

Strontium	(Sr)	108 atoms
Magnesium	(Mg)	93 atoms
Cadmium	(Cd)	5 atoms
Chlorine	(Cl)	22 atoms
Sodium	(Na)	75 atoms

The binding sites of Potassium atom in the Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit (pdb code 3i55). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit, PDB code: 3i55:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8401 b:0.9 occ:1.00 O6 0:G2102 3.2 67.8 1.0 OP1 0:U2539 3.3 61.0 1.0 O 0:HOH3610 3.5 53.8 1.0 O6 0:G2482 3.6 50.5 1.0 O2 0:U2535 3.8 54.1 1.0 C6 0:G2102 4.1 66.6 1.0 O3' 0:A2538 4.3 64.0 1.0 N7 0:G2102 4.3 66.9 1.0 P 0:U2539 4.4 63.6 1.0 O 0:HOH3614 4.4 46.0 1.0 O 0:HOH6125 4.5 45.6 1.0 O2' 0:U2535 4.5 52.2 1.0 C5 0:G2102 4.6 66.6 1.0 C2 0:U2535 4.6 51.8 1.0 C2' 0:U2535 4.7 51.8 1.0 C6 0:G2482 4.7 49.4 1.0 N7 0:G2482 4.7 49.4 1.0 O5' 0:U2539 4.8 62.5 1.0 N6 0:A2486 4.9 48.7 1.0

Potassium binding site 2 out of 2 in the Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Co-Crystal Structure of Mycalamide A Bound to the Large Ribosomal Subunit within 5.0Å range: probe atom residue distance (Å) B Occ 0:K8402 b:88.2 occ:1.00 NE M:ARG82 3.2 0.4 1.0 O M:HOH202 3.2 70.9 1.0 OP2 0:C162 3.3 39.0 1.0 O4 0:U172 3.4 51.6 1.0 O 0:HOH2969 3.4 32.7 1.0 O 0:HOH3273 3.4 71.5 1.0 O 0:HOH4003 3.7 38.8 1.0 CD M:ARG82 3.8 0.6 1.0 O 0:HOH7790 3.9 25.7 1.0 O 0:HOH7789 4.0 5.2 1.0 O4 0:U163 4.1 39.4 1.0 CZ M:ARG82 4.1 0.7 1.0 NH2 M:ARG82 4.2 0.9 1.0 P 0:C162 4.4 39.9 1.0 OP1 0:A169 4.4 45.5 1.0 C4 0:U172 4.5 48.9 1.0 OP1 0:C162 4.6 40.5 1.0 O5' 0:A161 4.8 41.0 1.0 CG M:ARG82 4.9 0.1 1.0 O3' 0:A161 4.9 39.8 1.0 N4 0:C171 4.9 49.8 1.0 OP2 0:A169 5.0 44.2 1.0

G.Gurel, G.Blaha, T.A.Steitz, P.B.Moore. Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula Marismortui. Antimicrob.Agents Chemother. V. 53 5010 2009.
ISSN: ISSN 0066-4804
PubMed: 19738021
DOI: 10.1128/AAC.00817-09