Atomistry » Potassium » PDB 3du0-3f2t » 3eui
Atomistry »
  Potassium »
    PDB 3du0-3f2t »
      3eui »

Potassium in PDB 3eui: A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell

Protein crystallography data

The structure of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell, PDB code: 3eui was solved by N.H.Campbell, G.Parkinson, S.Neidle, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 27.68 / 2.20
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 55.356, 42.542, 48.636, 90.00, 90.00, 90.00
R / Rfree (%) 23.4 / 28.5

Potassium Binding Sites:

The binding sites of Potassium atom in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell (pdb code 3eui). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 8 binding sites of Potassium where determined in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell, PDB code: 3eui:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Potassium binding site 1 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 1 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K50

b:21.1
occ:1.00
 O6 B:DG16 2.7 22.4 1.0
O6 A:DG12 2.7 13.1 1.0
O6 A:DG1 2.8 12.2 1.0
O6 A:DG11 2.8 7.0 1.0
O6 B:DG21 2.8 12.8 1.0
O6 A:DG2 2.8 13.5 1.0
O6 B:DG22 2.9 14.5 1.0
O6 B:DG15 3.0 9.6 1.0
K A:K51 3.5 18.2 1.0
K B:K49 3.5 20.9 1.0
C6 A:DG11 3.6 8.3 1.0
C6 B:DG16 3.6 20.3 1.0
C6 A:DG1 3.6 12.1 1.0
C6 A:DG12 3.7 13.5 1.0
C6 B:DG15 3.8 11.4 1.0
C6 A:DG2 3.8 14.8 1.0
C6 B:DG21 3.8 11.0 1.0
N1 B:DG16 3.8 17.7 1.0
C6 B:DG22 3.8 10.6 1.0
N1 A:DG11 3.9 6.5 1.0
N1 A:DG1 3.9 9.9 1.0
N1 A:DG12 4.0 9.6 1.0
N1 B:DG15 4.0 11.8 1.0
N1 B:DG22 4.1 9.4 1.0
N1 A:DG2 4.2 15.6 1.0
N1 B:DG21 4.2 10.9 1.0
C5 A:DG11 4.7 7.5 1.0
C5 A:DG1 4.9 14.1 1.0
C5 B:DG15 4.9 11.1 1.0
C5 A:DG2 4.9 14.4 1.0
C5 B:DG16 5.0 19.2 1.0
C5 A:DG12 5.0 14.4 1.0
C5 B:DG21 5.0 13.4 1.0

Potassium binding site 2 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 2 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K51

b:18.2
occ:1.00
 O6 A:DG2 2.6 13.5 1.0
O6 A:DG10 2.6 18.6 1.0
O6 B:DG23 2.8 10.8 1.0
O6 B:DG22 2.8 14.5 1.0
O6 B:DG14 2.8 8.9 1.0
O6 A:DG11 2.9 7.0 1.0
O6 A:DG3 3.0 20.1 1.0
O6 B:DG15 3.0 9.6 1.0
K A:K50 3.5 21.1 1.0
C6 A:DG2 3.5 14.8 1.0
C6 A:DG10 3.5 16.0 1.0
K A:K52 3.5 21.5 1.0
C6 B:DG14 3.6 10.8 1.0
C6 B:DG23 3.6 12.9 1.0
C6 B:DG22 3.7 10.6 1.0
N1 A:DG10 3.8 14.9 1.0
C6 A:DG11 3.8 8.3 1.0
N1 A:DG2 3.9 15.6 1.0
N1 B:DG23 3.9 12.8 1.0
N1 B:DG14 4.0 10.0 1.0
C6 A:DG3 4.0 19.1 1.0
C6 B:DG15 4.0 11.4 1.0
N1 B:DG22 4.0 9.4 1.0
N1 A:DG11 4.1 6.5 1.0
N1 A:DG3 4.4 18.4 1.0
N1 B:DG15 4.4 11.8 1.0
C5 A:DG2 4.6 14.4 1.0
C5 A:DG10 4.7 15.2 1.0
C5 B:DG14 4.8 11.8 1.0
C5 B:DG22 4.8 11.6 1.0
C5 B:DG23 4.9 14.4 1.0

Potassium binding site 3 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 3 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K52

b:21.5
occ:1.00
 O6 A:DG4 2.7 13.7 1.0
O6 B:DG13 2.7 16.8 1.0
O6 A:DG9 2.7 12.7 1.0
O6 B:DG14 2.8 8.9 1.0
O6 A:DG3 2.8 20.1 1.0
O6 A:DG10 3.0 18.6 1.0
O6 B:DG24 3.0 13.5 1.0
O6 B:DG23 3.1 10.8 1.0
K A:K51 3.5 18.2 1.0
C6 B:DG13 3.6 16.1 1.0
C6 B:DG14 3.6 10.8 1.0
C6 A:DG4 3.6 15.5 1.0
C6 A:DG9 3.7 13.0 1.0
C6 A:DG3 3.7 19.1 1.0
N1 A:DG4 3.8 15.1 1.0
C6 A:DG10 3.8 16.0 1.0
N1 B:DG13 3.8 15.6 1.0
N1 B:DG14 3.9 10.0 1.0
C6 B:DG23 3.9 12.9 1.0
C6 B:DG24 3.9 14.1 1.0
N1 A:DG10 4.0 14.9 1.0
N1 A:DG9 4.1 12.7 1.0
N1 B:DG24 4.1 11.7 1.0
N1 A:DG3 4.1 18.4 1.0
N1 B:DG23 4.1 12.8 1.0
O2 A:DT6 4.5 9.0 1.0
C5 A:DG3 4.8 19.2 1.0
C5 B:DG13 4.8 16.4 1.0
C5 B:DG14 4.8 11.8 1.0
C5 A:DG9 4.9 13.9 1.0
C5 A:DG4 5.0 14.1 1.0

Potassium binding site 4 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 4 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K49

b:20.9
occ:1.00
 O B:HOH66 2.6 29.4 1.0
O2 B:DT19 2.6 20.2 1.0
O6 A:DG12 2.6 13.1 1.0
O2 B:DT17 2.7 14.7 1.0
O6 B:DG16 2.8 22.4 1.0
O6 A:DG1 3.1 12.2 1.0
O B:HOH65 3.2 16.5 1.0
O6 B:DG21 3.2 12.8 1.0
C6 A:DG12 3.4 13.5 1.0
C2 B:DT17 3.4 17.4 1.0
K A:K50 3.5 21.1 1.0
C2 B:DT19 3.5 17.7 1.0
N3 B:DT17 3.5 17.2 1.0
C6 B:DG16 3.6 20.3 1.0
N1 A:DG12 3.7 9.6 1.0
N3 B:DT19 3.8 18.4 1.0
N1 B:DG16 4.0 17.7 1.0
C6 A:DG1 4.0 12.1 1.0
C6 B:DG21 4.0 11.0 1.0
N1 A:DG1 4.2 9.9 1.0
N1 B:DG21 4.2 10.9 1.0
O2 B:DT18 4.2 18.4 1.0
C5 A:DG12 4.5 14.4 1.0
C5 B:DG16 4.6 19.2 1.0
C2 B:DT18 4.6 17.4 1.0
N3 B:DT18 4.7 16.5 1.0
N1 B:DT19 4.7 18.4 1.0
N1 B:DT17 4.8 18.0 1.0
C4 B:DT17 4.8 17.9 1.0
C2 A:DG12 4.9 11.8 1.0
O4' B:DT20 5.0 18.1 1.0

Potassium binding site 5 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 5 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K54

b:17.5
occ:1.00
 O6 C:DG25 2.6 12.6 1.0
O6 C:DG26 2.7 16.5 1.0
O6 C:DG36 2.8 15.4 1.0
O6 D:DG45 2.8 14.3 1.0
O6 C:DG35 2.9 14.2 1.0
O6 D:DG40 2.9 15.0 1.0
O6 D:DG46 3.0 17.4 1.0
O6 D:DG39 3.0 15.6 1.0
K C:K55 3.5 11.7 1.0
C6 C:DG25 3.5 11.8 1.0
K D:K53 3.5 22.7 1.0
C6 C:DG35 3.6 15.4 1.0
C6 C:DG26 3.7 17.8 1.0
C6 D:DG45 3.7 12.8 1.0
C6 D:DG40 3.8 15.2 1.0
C6 C:DG36 3.8 18.2 1.0
N1 C:DG25 3.8 9.6 1.0
C6 D:DG46 3.8 12.7 1.0
C6 D:DG39 3.8 12.2 1.0
N1 C:DG35 3.8 14.1 1.0
N1 D:DG40 3.9 14.0 1.0
N1 D:DG46 4.0 13.2 1.0
N1 D:DG45 4.1 15.1 1.0
N1 C:DG26 4.1 17.9 1.0
N1 D:DG39 4.1 12.9 1.0
N1 C:DG36 4.1 16.3 1.0
C5 C:DG35 4.7 15.2 1.0
C5 C:DG25 4.7 11.7 1.0
C5 C:DG26 4.9 17.0 1.0
C5 D:DG45 4.9 14.2 1.0
C5 D:DG39 4.9 12.4 1.0

Potassium binding site 6 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 6 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K55

b:11.7
occ:1.00
 O6 C:DG26 2.6 16.5 1.0
O6 C:DG34 2.7 20.7 1.0
O6 D:DG38 2.8 11.8 1.0
O6 C:DG35 2.8 14.2 1.0
O6 D:DG47 2.8 13.9 1.0
O6 D:DG46 2.8 17.4 1.0
O6 C:DG27 2.9 20.6 1.0
O6 D:DG39 3.0 15.6 1.0
K C:K54 3.5 17.5 1.0
C6 C:DG26 3.5 17.8 1.0
K C:K56 3.6 17.1 1.0
C6 C:DG34 3.6 18.5 1.0
C6 D:DG38 3.6 12.6 1.0
C6 D:DG46 3.7 12.7 1.0
C6 D:DG47 3.7 14.1 1.0
C6 C:DG35 3.7 15.4 1.0
N1 C:DG34 3.8 17.8 1.0
N1 C:DG26 3.9 17.9 1.0
C6 C:DG27 3.9 17.7 1.0
N1 D:DG46 3.9 13.2 1.0
N1 D:DG38 4.0 14.1 1.0
N1 C:DG35 4.0 14.1 1.0
N1 D:DG47 4.0 14.8 1.0
C6 D:DG39 4.0 12.2 1.0
N1 C:DG27 4.3 19.1 1.0
N1 D:DG39 4.4 12.9 1.0
C5 C:DG26 4.6 17.0 1.0
C5 D:DG38 4.8 13.6 1.0
C5 C:DG34 4.8 19.6 1.0
C5 D:DG46 4.9 13.4 1.0
C5 D:DG47 5.0 14.9 1.0

Potassium binding site 7 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 7 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K56

b:17.1
occ:1.00
 O6 C:DG33 2.6 16.3 1.0
O6 C:DG28 2.6 15.9 1.0
O6 D:DG37 2.7 15.8 1.0
O6 D:DG48 2.8 19.1 1.0
O6 D:DG38 2.8 11.8 1.0
O6 C:DG27 3.0 20.6 1.0
O6 C:DG34 3.1 20.7 1.0
O6 D:DG47 3.1 13.9 1.0
C6 C:DG33 3.6 16.1 1.0
K C:K55 3.6 11.7 1.0
C6 C:DG28 3.6 15.5 1.0
C6 D:DG37 3.6 15.5 1.0
C6 D:DG48 3.7 18.4 1.0
C6 D:DG38 3.7 12.6 1.0
N1 C:DG28 3.8 14.9 1.0
N1 D:DG37 3.8 14.1 1.0
C6 C:DG27 3.8 17.7 1.0
N1 C:DG33 3.9 17.0 1.0
C6 D:DG47 3.9 14.1 1.0
C6 C:DG34 4.0 18.5 1.0
N1 D:DG38 4.0 14.1 1.0
N1 D:DG48 4.0 17.3 1.0
N1 D:DG47 4.1 14.8 1.0
N1 C:DG27 4.2 19.1 1.0
N1 C:DG34 4.2 17.8 1.0
O2 C:DT30 4.4 12.8 1.0
C5 C:DG33 4.8 17.9 1.0
C5 C:DG27 4.9 18.8 1.0
C5 D:DG37 4.9 15.0 1.0
C5 C:DG28 4.9 13.8 1.0
C5 D:DG48 5.0 18.6 1.0
C5 D:DG38 5.0 13.6 1.0

Potassium binding site 8 out of 8 in 3eui

Go back to Potassium Binding Sites List in 3eui
Potassium binding site 8 out of 8 in the A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 8 of A Bimolecular Anti-Parallel-Stranded Oxytricha Nova Telomeric Quadruplex in Complex with A 3,6-Disubstituted Acridine Bsu-6042 in A Large Unit Cell within 5.0Å range:
probe atom residue distance (Å) B Occ
D:K53

b:22.7
occ:1.00
 O2 D:DT43 2.4 20.8 1.0
O2 D:DT41 2.7 16.7 1.0
O D:HOH130 2.7 33.6 1.0
O6 C:DG36 2.8 15.4 1.0
O6 D:DG45 3.0 14.3 1.0
O6 D:DG40 3.0 15.0 1.0
O6 C:DG25 3.1 12.6 1.0
O D:HOH92 3.3 12.9 1.0
C2 D:DT43 3.4 19.6 1.0
K C:K54 3.5 17.5 1.0
C2 D:DT41 3.6 17.8 1.0
C6 C:DG36 3.6 18.2 1.0
N3 D:DT43 3.7 20.0 1.0
C6 D:DG40 3.7 15.2 1.0
N3 D:DT41 3.8 17.5 1.0
C6 D:DG45 3.8 12.8 1.0
C6 C:DG25 3.9 11.8 1.0
N1 C:DG36 3.9 16.3 1.0
N1 D:DG45 4.0 15.1 1.0
N1 C:DG25 4.1 9.6 1.0
N1 D:DG40 4.1 14.0 1.0
O2 D:DT42 4.4 21.1 1.0
N1 D:DT43 4.6 19.0 1.0
C5 C:DG36 4.7 16.9 1.0
C5 D:DG40 4.7 14.9 1.0
C2 D:DT42 4.8 19.7 1.0
N1 D:DT41 4.9 18.3 1.0
N3 D:DT42 5.0 20.5 1.0

Reference:

N.H.Campbell, M.Patel, A.B.Tofa, R.Ghosh, G.N.Parkinson, S.Neidle. Selectivity in Ligand Recognition of G-Quadruplex Loops. Biochemistry V. 48 1675 2009.
ISSN: ISSN 0006-2960
PubMed: 19173611
DOI: 10.1021/BI802233V
Page generated: Sat Aug 9 04:47:52 2025

Last articles

Na in 4UWV
Na in 4UWU
Na in 4UWO
Na in 4UWH
Na in 4UWN
Na in 4UUG
Na in 4UUI
Na in 4UUB
Na in 4UUA
Na in 4UU8
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy