Potassium in PDB 2hdu: Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid

All present enzymatic activity of Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid:
3.5.2.6;

The structure of Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid, PDB code: 2hdu was solved by K.Babaoglu, B.K.Shoichet, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	87.04 / 1.49
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	117.905, 77.057, 97.520, 90.00, 116.86, 90.00
R / Rfree (%)	13.5 / 16.8

The binding sites of Potassium atom in the Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid (pdb code 2hdu). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid, PDB code: 2hdu:

Potassium binding site 1 out of 1 in the Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Ampc Beta-Lactamase in Complex with 2-Acetamidothiophene-3-Carboxylic Acid within 5.0Å range: probe atom residue distance (Å) B Occ B:K2001 b:18.9 occ:1.00 O B:HOH2256 3.0 26.3 1.0 O A:HOH1228 3.1 26.3 1.0 O B:HOH2384 3.3 34.0 1.0 CA B:PRO303 3.6 10.4 1.0 CA A:PRO303 3.6 10.9 1.0 CD A:PRO304 3.9 11.7 1.0 CA B:THR302 3.9 11.5 1.0 CG2 B:THR302 3.9 15.4 1.0 CD B:PRO304 4.0 11.9 1.0 CA A:THR302 4.0 11.9 1.0 CG2 A:THR302 4.0 15.3 1.0 O B:ILE301 4.2 11.8 1.0 O B:HOH2490 4.2 24.6 1.0 CB A:PRO303 4.2 11.8 1.0 CB B:PRO303 4.2 10.2 1.0 O A:HOH1478 4.3 18.1 0.5 CB B:THR302 4.3 12.2 1.0 O A:ILE301 4.3 11.1 1.0 N B:PRO303 4.3 10.3 1.0 N A:PRO303 4.4 10.9 1.0 CB A:THR302 4.4 13.1 1.0 OG1 B:THR302 4.4 16.4 1.0 OG1 A:THR302 4.4 17.1 1.0 C B:THR302 4.5 10.0 1.0 C B:PRO303 4.6 10.6 1.0 C A:PRO303 4.6 10.7 1.0 N A:PRO304 4.6 10.6 1.0 N B:PRO304 4.6 11.3 1.0 C A:THR302 4.6 10.5 1.0 O A:HOH1290 4.7 40.7 1.0 O B:HOH2231 4.8 27.1 1.0 CG A:PRO304 4.8 11.9 1.0 N B:THR302 4.9 11.1 1.0 O A:HOH1239 4.9 29.1 1.0 CG B:PRO304 4.9 13.8 1.0 C B:ILE301 4.9 11.2 1.0 N A:THR302 5.0 11.0 1.0

K.Babaoglu, B.K.Shoichet. Deconstructing Fragment-Based Inhibitor Discovery Nat.Chem.Biol. V. 2 720 2006.
ISSN: ISSN 1552-4450
PubMed: 17072304
DOI: 10.1038/NCHEMBIO831