Potassium in PDB 1u1e: Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau)

All present enzymatic activity of Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau):
2.4.2.3;

The structure of Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau), PDB code: 1u1e was solved by W.Bu, E.C.Settembre, S.E.Ealick, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	48.80 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	91.076, 125.690, 140.899, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 23.5

The binding sites of Potassium atom in the Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau) (pdb code 1u1e). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau), PDB code: 1u1e:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau) within 5.0Å range: probe atom residue distance (Å) B Occ A:K1002 b:63.1 occ:1.00 O A:ILE69 2.8 10.5 1.0 O B:ILE69 2.8 11.0 1.0 OG B:SER73 2.9 10.8 1.0 OE1 A:GLU49 3.0 12.0 1.0 OE1 B:GLU49 3.0 12.1 1.0 OG A:SER73 3.0 10.0 1.0 O B:HOH4471 3.1 41.4 1.0 CB B:SER73 3.5 11.0 1.0 CB A:SER73 3.6 10.3 1.0 N A:ILE69 3.8 10.2 1.0 N B:ILE69 3.8 11.2 1.0 C A:ILE69 3.8 10.4 1.0 C B:ILE69 3.9 11.1 1.0 CD B:GLU49 4.1 12.3 1.0 CD A:GLU49 4.1 12.2 1.0 C B:GLY68 4.3 11.4 1.0 C A:GLY68 4.3 9.9 1.0 CA A:ILE69 4.3 10.3 1.0 CA B:ILE69 4.3 11.1 1.0 CA B:GLY68 4.4 11.5 1.0 CA A:GLY68 4.4 9.8 1.0 CG B:GLU49 4.5 12.0 1.0 CG A:GLU49 4.5 11.6 1.0 CB A:ILE69 4.7 10.3 1.0 CA B:SER73 4.8 10.9 1.0 CB B:ILE69 4.8 11.0 1.0 O B:THR67 4.8 11.9 1.0 O A:THR67 4.8 9.3 1.0 CA A:SER73 4.9 10.3 1.0 N B:SER73 4.9 11.1 1.0 N A:SER73 4.9 10.2 1.0 N B:GLY70 5.0 11.1 1.0 N A:GLY70 5.0 10.4 1.0

Potassium binding site 2 out of 3 in the Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau) within 5.0Å range: probe atom residue distance (Å) B Occ C:K1003 b:69.0 occ:1.00 OG C:SER73 2.9 9.9 1.0 O D:ILE69 2.9 9.0 1.0 O C:ILE69 2.9 10.1 1.0 OG D:SER73 3.0 9.5 1.0 OE1 C:GLU49 3.1 11.7 1.0 OE1 D:GLU49 3.1 11.8 1.0 CB C:SER73 3.8 9.9 1.0 CB D:SER73 3.8 9.8 1.0 N C:ILE69 3.8 10.3 1.0 N D:ILE69 3.9 9.4 1.0 C C:ILE69 4.0 10.1 1.0 C D:ILE69 4.0 9.2 1.0 CD C:GLU49 4.1 11.7 1.0 CD D:GLU49 4.2 12.0 1.0 C C:GLY68 4.4 10.4 1.0 CA C:ILE69 4.4 10.1 1.0 CA D:ILE69 4.4 9.2 1.0 C D:GLY68 4.5 9.5 1.0 CA C:GLY68 4.5 10.5 1.0 CA D:GLY68 4.5 9.6 1.0 CG C:GLU49 4.6 11.6 1.0 CG D:GLU49 4.6 12.0 1.0 O C:THR67 4.8 10.7 1.0 CB C:ILE69 4.9 10.1 1.0 CB D:ILE69 4.9 9.2 1.0 N C:SER73 5.0 9.7 1.0 CA C:SER73 5.0 9.9 1.0 N D:SER73 5.0 9.8 1.0 O D:THR67 5.0 9.9 1.0

Potassium binding site 3 out of 3 in the Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau)


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Structure of E. Coli Uridine Phosphorylase Complexed to 5(Phenylseleno)Acyclouridine (Psau) within 5.0Å range: probe atom residue distance (Å) B Occ E:K1001 b:53.3 occ:1.00 OG E:SER73 2.8 8.5 1.0 O E:ILE69 2.8 9.4 1.0 O F:ILE69 2.8 9.1 1.0 OE1 F:GLU49 2.9 10.6 1.0 OG F:SER73 2.9 9.2 1.0 OE1 E:GLU49 3.0 8.4 1.0 CB F:SER73 3.6 9.8 1.0 CB E:SER73 3.6 8.7 1.0 N E:ILE69 3.7 9.3 1.0 N F:ILE69 3.8 9.1 1.0 C E:ILE69 3.8 9.3 1.0 C F:ILE69 3.9 9.1 1.0 CD F:GLU49 4.0 10.6 1.0 CD E:GLU49 4.1 8.6 1.0 C E:GLY68 4.3 9.4 1.0 CA E:ILE69 4.3 9.3 1.0 C F:GLY68 4.3 9.2 1.0 CA F:ILE69 4.3 9.0 1.0 CA E:GLY68 4.4 9.5 1.0 CA F:GLY68 4.4 9.4 1.0 CG E:GLU49 4.5 8.4 1.0 CG F:GLU49 4.5 10.1 1.0 CB E:ILE69 4.8 9.3 1.0 CB F:ILE69 4.8 9.0 1.0 O F:THR67 4.8 9.8 1.0 CA E:SER73 4.8 8.7 1.0 N E:SER73 4.8 8.7 1.0 O E:THR67 4.8 9.9 1.0 CA F:SER73 4.8 9.8 1.0 N F:SER73 4.9 9.6 1.0 N E:GLY70 5.0 9.3 1.0

W.Bu, E.C.Settembre, M.H.El Kouni, S.E.Ealick. Structural Basis For Inhibition of Escherichia Coli Uridine Phosphorylase By 5-Substituted Acyclouridines. Acta Crystallogr.,Sect.D V. 61 863 2005.
ISSN: ISSN 0907-4449
PubMed: 15983408
DOI: 10.1107/S0907444905007882