Atomistry » Potassium » PDB 1m5h-1o07 » 1nf7
Atomistry »
  Potassium »
    PDB 1m5h-1o07 »
      1nf7 »

Potassium in PDB 1nf7: Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide

Enzymatic activity of Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide

All present enzymatic activity of Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide:
1.1.1.205;

Protein crystallography data

The structure of Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide, PDB code: 1nf7 was solved by D.Risal, M.D.Strickler, B.M.Goldstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.24 / 2.65
Space group I 4
Cell size a, b, c (Å), α, β, γ (°) 146.580, 146.580, 128.920, 90.00, 90.00, 90.00
R / Rfree (%) 23.8 / 27.7

Potassium Binding Sites:

The binding sites of Potassium atom in the Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide (pdb code 1nf7). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide, PDB code: 1nf7:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in 1nf7

Go back to Potassium Binding Sites List in 1nf7
Potassium binding site 1 out of 2 in the Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K902

b:0.8
occ:1.00
O A:CYS331 2.7 75.3 1.0
O A:GLY328 2.9 74.8 1.0
O A:HOH944 3.2 86.2 1.0
O A:GLY326 3.3 77.2 1.0
C A:GLY326 3.7 77.3 1.0
C A:SER327 3.7 95.9 1.0
O A:SER327 3.9 96.1 1.0
C A:CYS331 3.9 75.3 1.0
C A:GLY328 4.0 74.5 1.0
CA A:SER327 4.0 95.8 1.0
N A:SER327 4.1 95.8 1.0
N A:GLY328 4.1 75.2 1.0
CB A:CYS331 4.5 46.7 1.0
CA A:GLY326 4.6 77.0 1.0
CA A:CYS331 4.6 75.1 1.0
CA A:GLY328 4.6 74.8 1.0
NE2 A:GLN334 4.7 43.9 1.0
N A:CYS331 4.8 75.0 1.0
N A:ILE332 4.8 86.5 1.0
CA A:ILE332 4.9 86.6 1.0
N A:SER329 5.0 28.0 1.0

Potassium binding site 2 out of 2 in 1nf7

Go back to Potassium Binding Sites List in 1nf7
Potassium binding site 2 out of 2 in the Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Ternary Complex of the Human Type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2- Mycophenolic Adenine Dinucleotide within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K901

b:0.7
occ:1.00
O B:CYS331 2.8 84.8 1.0
O B:GLY328 3.0 49.0 1.0
O B:HOH947 3.1 71.0 1.0
O B:GLY326 3.2 64.1 1.0
C B:GLY326 3.7 64.2 1.0
C B:SER327 3.7 81.7 1.0
O B:SER327 3.8 81.9 1.0
C B:CYS331 3.9 84.6 1.0
CA B:SER327 3.9 81.8 1.0
N B:SER327 4.0 81.8 1.0
C B:GLY328 4.0 48.9 1.0
N B:GLY328 4.1 49.5 1.0
CB B:CYS331 4.5 36.3 1.0
CA B:GLY326 4.6 64.0 1.0
CA B:GLY328 4.7 49.1 1.0
CA B:CYS331 4.7 84.3 1.0
N B:ILE332 4.8 71.0 1.0
N B:CYS331 4.8 84.2 1.0
CA B:ILE332 4.9 70.8 1.0

Reference:

D.Risal, M.D.Strickler, B.M.Goldstein. Crystal Structure of Human Inosine Monophosphate Dehydrogenase Type II Complexed with the Mpa/Nad Analog C2-Mad To Be Published.
Page generated: Mon Aug 12 05:01:03 2024

Last articles

Zn in 9MJ5
Zn in 9HNW
Zn in 9G0L
Zn in 9FNE
Zn in 9DZN
Zn in 9E0I
Zn in 9D32
Zn in 9DAK
Zn in 8ZXC
Zn in 8ZUF
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy