Potassium in PDB 1bl8: Potassium Channel (Kcsa) From Streptomyces Lividans

The structure of Potassium Channel (Kcsa) From Streptomyces Lividans, PDB code: 1bl8 was solved by D.A.Doyle, J.M.Cabral, R.A.Pfuetzner, A.Kuo, J.M.Gulbis, S.L.Cohen, B.T.Chait, R.Mackinnon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	10.00 / 3.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	128.780, 68.930, 112.040, 90.00, 124.63, 90.00
R / Rfree (%)	28 / 29

The binding sites of Potassium atom in the Potassium Channel (Kcsa) From Streptomyces Lividans (pdb code 1bl8). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the Potassium Channel (Kcsa) From Streptomyces Lividans, PDB code: 1bl8:
Jump to Potassium binding site number: 1; 2; 3;

Potassium binding site 1 out of 3 in the Potassium Channel (Kcsa) From Streptomyces Lividans


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Potassium Channel (Kcsa) From Streptomyces Lividans within 5.0Å range: probe atom residue distance (Å) B Occ A:K401 b:57.7 occ:1.00 O B:TYR78 3.1 53.3 1.0 O D:TYR78 3.1 47.6 1.0 O A:TYR78 3.1 62.8 1.0 O B:GLY77 3.1 0.6 1.0 O A:GLY77 3.1 0.3 1.0 O C:GLY77 3.1 0.6 1.0 O D:GLY77 3.1 0.3 1.0 O C:TYR78 3.2 80.0 1.0 O B:HOH500 3.4 66.2 1.0 C B:TYR78 3.6 53.3 1.0 C A:TYR78 3.7 62.8 1.0 C D:TYR78 3.7 47.6 1.0 C C:TYR78 3.8 80.0 1.0 N B:GLY79 4.2 41.5 1.0 N A:GLY79 4.2 72.4 1.0 N D:GLY79 4.2 77.9 1.0 C B:GLY77 4.2 0.6 1.0 CA B:GLY79 4.2 41.5 1.0 C A:GLY77 4.3 0.3 1.0 CA A:GLY79 4.3 72.4 1.0 C D:GLY77 4.3 0.3 1.0 CA D:GLY79 4.3 77.9 1.0 N C:GLY79 4.3 74.9 1.0 C C:GLY77 4.3 0.6 1.0 CA C:GLY79 4.4 74.9 1.0 CA B:TYR78 4.4 53.3 1.0 CA A:TYR78 4.5 62.8 1.0 CA D:TYR78 4.5 47.6 1.0 CA C:TYR78 4.5 80.0 1.0 N B:TYR78 4.8 53.3 1.0 N A:TYR78 4.9 62.8 1.0 N D:TYR78 4.9 47.6 1.0 N C:TYR78 4.9 80.0 1.0

Potassium binding site 2 out of 3 in the Potassium Channel (Kcsa) From Streptomyces Lividans


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Potassium Channel (Kcsa) From Streptomyces Lividans within 5.0Å range: probe atom residue distance (Å) B Occ A:K402 b:74.8 occ:1.00 K A:K403 3.3 75.5 1.0 O C:THR75 3.3 65.2 1.0 O B:THR75 3.4 73.5 1.0 O D:THR75 3.4 67.2 1.0 O A:THR75 3.4 71.5 1.0 O B:VAL76 3.4 0.6 1.0 O D:VAL76 3.4 0.1 1.0 O A:VAL76 3.4 0.8 1.0 O C:VAL76 3.5 0.7 1.0 C B:VAL76 3.6 0.6 1.0 CA B:VAL76 3.6 0.6 1.0 C D:VAL76 3.6 0.1 1.0 CA D:VAL76 3.7 0.1 1.0 C A:VAL76 3.7 0.8 1.0 CA C:VAL76 3.7 0.7 1.0 CA A:VAL76 3.7 0.8 1.0 C C:VAL76 3.7 0.7 1.0 O B:HOH500 3.9 66.2 1.0 C C:THR75 4.0 65.2 1.0 C B:THR75 4.0 73.5 1.0 C D:THR75 4.0 67.2 1.0 C A:THR75 4.0 71.5 1.0 N B:VAL76 4.1 0.6 1.0 N C:VAL76 4.1 0.7 1.0 N D:VAL76 4.1 0.1 1.0 N A:VAL76 4.2 0.8 1.0 OG1 C:THR75 4.3 51.9 1.0 OG1 B:THR75 4.3 51.4 1.0 OG1 A:THR75 4.3 78.6 1.0 OG1 D:THR75 4.3 71.1 1.0 N B:GLY77 4.5 0.6 1.0 N D:GLY77 4.5 0.3 1.0 N A:GLY77 4.5 0.3 1.0 N C:GLY77 4.6 0.6 1.0 CB B:VAL76 5.0 55.2 1.0 CB D:VAL76 5.0 82.8 1.0

Potassium binding site 3 out of 3 in the Potassium Channel (Kcsa) From Streptomyces Lividans


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Potassium Channel (Kcsa) From Streptomyces Lividans within 5.0Å range: probe atom residue distance (Å) B Occ A:K403 b:75.5 occ:1.00 O B:THR75 2.9 73.5 1.0 OG1 C:THR75 3.0 51.9 1.0 OG1 B:THR75 3.0 51.4 1.0 O C:THR75 3.0 65.2 1.0 O A:THR75 3.1 71.5 1.0 O D:THR75 3.1 67.2 1.0 OG1 A:THR75 3.2 78.6 1.0 OG1 D:THR75 3.2 71.1 1.0 K A:K402 3.3 74.8 1.0 C B:THR75 4.1 73.5 1.0 C C:THR75 4.2 65.2 1.0 C A:THR75 4.2 71.5 1.0 C D:THR75 4.3 67.2 1.0 CB C:THR75 4.4 51.9 1.0 CB B:THR75 4.4 51.4 1.0 CB A:THR75 4.5 78.6 1.0 CB D:THR75 4.6 71.1 1.0 O B:THR74 4.8 23.1 1.0 CA B:THR75 4.9 73.5 1.0 CG2 C:THR75 4.9 51.9 1.0 O C:THR74 4.9 7.1 1.0 CG2 B:THR75 4.9 51.4 1.0 CA C:THR75 5.0 65.2 1.0 O A:THR74 5.0 48.2 1.0

D.A.Doyle, J.Morais Cabral, R.A.Pfuetzner, A.Kuo, J.M.Gulbis, S.L.Cohen, B.T.Chait, R.Mackinnon. The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity. Science V. 280 69 1998.
ISSN: ISSN 0036-8075
PubMed: 9525859
DOI: 10.1126/SCIENCE.280.5360.69