Potassium in PDB 8wgr: Cryo-Em Structure of Inward-Open State Human Norepinephrine Transporter Net Bound with Antidepressant Desipramine in Kcl Condition.

The structure of Cryo-Em Structure of Inward-Open State Human Norepinephrine Transporter Net Bound with Antidepressant Desipramine in Kcl Condition. also contains other interesting chemical elements:

Chlorine

(Cl)

1 atom

The binding sites of Potassium atom in the Cryo-Em Structure of Inward-Open State Human Norepinephrine Transporter Net Bound with Antidepressant Desipramine in Kcl Condition. (pdb code 8wgr). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Cryo-Em Structure of Inward-Open State Human Norepinephrine Transporter Net Bound with Antidepressant Desipramine in Kcl Condition., PDB code: 8wgr:

Potassium binding site 1 out of 1 in the Cryo-Em Structure of Inward-Open State Human Norepinephrine Transporter Net Bound with Antidepressant Desipramine in Kcl Condition.


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo-Em Structure of Inward-Open State Human Norepinephrine Transporter Net Bound with Antidepressant Desipramine in Kcl Condition. within 5.0Å range: probe atom residue distance (Å) B Occ A:K704 b:70.3 occ:1.00 OD1 A:ASN78 2.7 44.9 1.0 O A:SER318 2.8 55.1 1.0 OD1 A:ASN350 2.8 54.7 1.0 OD2 A:ASP75 2.9 52.8 1.0 O A:ALA73 2.9 60.6 1.0 HB3 A:ASP75 3.4 51.8 1.0 HG A:SER318 3.4 47.8 1.0 H183 A:DSM701 3.7 45.4 1.0 OG A:SER318 3.7 54.9 1.0 C A:ALA73 3.7 56.6 1.0 HA A:ALA73 3.7 59.0 1.0 CG A:ASP75 3.8 51.3 1.0 CG A:ASN78 3.8 47.5 1.0 C A:SER318 3.8 41.4 1.0 CG A:ASN350 3.9 57.2 1.0 HD22 A:ASN78 3.9 46.2 1.0 HD22 A:ASN350 3.9 54.6 1.0 CB A:ASP75 4.0 49.6 1.0 HA A:SER318 4.1 45.8 1.0 HN2 A:DSM701 4.1 45.9 1.0 HB3 A:ALA77 4.1 46.2 1.0 ND2 A:ASN78 4.2 53.1 1.0 CA A:ALA73 4.3 52.1 1.0 HA A:VAL74 4.3 60.6 1.0 H182 A:DSM701 4.3 44.4 1.0 H A:ASP75 4.3 51.7 1.0 ND2 A:ASN350 4.3 58.2 1.0 C18 A:DSM701 4.3 40.1 1.0 CA A:SER318 4.4 36.9 1.0 HA A:LEU319 4.4 48.4 1.0 N A:ASP75 4.4 52.2 1.0 H A:ASN78 4.4 47.1 1.0 N A:VAL74 4.5 65.1 1.0 C A:VAL74 4.6 62.4 1.0 CB A:SER318 4.6 45.6 1.0 N2 A:DSM701 4.7 47.9 1.0 O A:PHE72 4.7 69.2 1.0 CA A:VAL74 4.7 59.3 1.0 HB2 A:ASP75 4.8 51.1 1.0 HB1 A:ALA73 4.8 60.3 1.0 OD1 A:ASP75 4.8 53.8 1.0 N A:LEU319 4.8 46.2 1.0 CA A:ASP75 4.9 44.1 1.0 HA A:ASN350 4.9 53.6 1.0 CB A:ASN78 5.0 43.5 1.0

J.Tan, Y.Xiao, F.Kong, X.Zhang, H.Xu, A.Zhu, Y.Liu, J.Lei, J.Tian, Y.Yuan, C.Yan. Molecular Basis of Human Noradrenaline Transporter Reuptake and Inhibition. Nature 2024.
ISSN: ESSN 1476-4687
DOI: 10.1038/S41586-024-07719-Z