Potassium in PDB 8tcb: Structure of Human C4B-Binding Protein Alpha Chain Ccp Domains 1 and 2 in Complex with the Hypervariable Region of Group A Streptococcus M87 Protein

The structure of Structure of Human C4B-Binding Protein Alpha Chain Ccp Domains 1 and 2 in Complex with the Hypervariable Region of Group A Streptococcus M87 Protein, PDB code: 8tcb was solved by M.A.Mcgowan, P.Kolesinski, P.Ghosh, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.81 / 2.69
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	43.176, 73.802, 190.398, 90, 90, 90
R / Rfree (%)	23.5 / 27.8

The binding sites of Potassium atom in the Structure of Human C4B-Binding Protein Alpha Chain Ccp Domains 1 and 2 in Complex with the Hypervariable Region of Group A Streptococcus M87 Protein (pdb code 8tcb). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Structure of Human C4B-Binding Protein Alpha Chain Ccp Domains 1 and 2 in Complex with the Hypervariable Region of Group A Streptococcus M87 Protein, PDB code: 8tcb:

Potassium binding site 1 out of 1 in the Structure of Human C4B-Binding Protein Alpha Chain Ccp Domains 1 and 2 in Complex with the Hypervariable Region of Group A Streptococcus M87 Protein


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Human C4B-Binding Protein Alpha Chain Ccp Domains 1 and 2 in Complex with the Hypervariable Region of Group A Streptococcus M87 Protein within 5.0Å range: probe atom residue distance (Å) B Occ A:K201 b:72.1 occ:1.00 OD2 D:ASP94 3.3 55.0 1.0 ND1 A:HIS41 3.5 71.6 1.0 OG A:SER42 3.9 45.0 1.0 N A:SER42 4.0 42.0 1.0 OE1 D:GLN90 4.2 74.8 1.0 CG D:ASP94 4.3 46.6 1.0 CE1 A:HIS41 4.4 76.7 1.0 CG A:HIS41 4.4 56.7 1.0 CA A:HIS41 4.4 46.5 1.0 CB A:HIS41 4.5 54.0 1.0 OD1 D:ASP94 4.5 59.1 1.0 CB A:SER42 4.5 50.3 1.0 C A:HIS41 4.8 42.5 1.0 CA A:SER42 4.9 57.0 1.0

P.Kolesinski, M.Mcgowan, A.Botteaux, P.R.Smeesters, P.Ghosh. Conservation of C4BP-Binding Sequence Patterns in Streptococcus Pyogenes M and Enn Proteins. J.Biol.Chem. V. 300 07478 2024.
ISSN: ESSN 1083-351X
PubMed: 38879009
DOI: 10.1016/J.JBC.2024.107478