Potassium in PDB 8r6k: Crystal Structure of Candida Glabrata BDF1 Bromodomain 1 Bound to A Phenyltriazine Ligand

The structure of Crystal Structure of Candida Glabrata BDF1 Bromodomain 1 Bound to A Phenyltriazine Ligand, PDB code: 8r6k was solved by C.Petosa, K.Wei, C.E.Mckenna, J.Govin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	57.46 / 2.19
Space group	I 4 2 2
Cell size a, b, c (Å), α, β, γ (°)	128.7, 128.7, 148.209, 90, 90, 90
R / Rfree (%)	20.9 / 24.8

The binding sites of Potassium atom in the Crystal Structure of Candida Glabrata BDF1 Bromodomain 1 Bound to A Phenyltriazine Ligand (pdb code 8r6k). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure of Candida Glabrata BDF1 Bromodomain 1 Bound to A Phenyltriazine Ligand, PDB code: 8r6k:

Potassium binding site 1 out of 1 in the Crystal Structure of Candida Glabrata BDF1 Bromodomain 1 Bound to A Phenyltriazine Ligand


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Candida Glabrata BDF1 Bromodomain 1 Bound to A Phenyltriazine Ligand within 5.0Å range: probe atom residue distance (Å) B Occ A:K304 b:45.6 occ:1.00 O A:ASN209 2.7 20.4 1.0 O A:HOH480 2.7 33.8 1.0 O A:HOH447 3.0 33.0 1.0 O A:HOH483 3.4 27.4 1.0 C A:ASN209 3.6 22.9 1.0 CA A:ASN209 3.9 25.7 1.0 O A:HOH479 4.1 30.3 1.0 CB A:ASN209 4.3 15.2 1.0 CB A:ALA213 4.8 18.3 1.0 N A:GLY210 4.8 16.1 1.0 O A:HOH424 4.8 27.5 1.0 OD1 A:ASN209 4.9 17.6 1.0

K.Wei, M.Arlotto, J.M.Overhulse, T.A.Dinh, Y.Zhou, N.J.Dupper, J.Yang, B.A.Kashemirov, H.Dawi, C.Garnaud, G.Bourgine, F.Mietton, M.Champleboux, A.Larabi, Y.Hayat, R.L.Indorato, M.Noirclerc-Savoye, D.Skoufias, M.Cornet, G.Rabut, C.E.Mckenna, C.Petosa, J.Govin. Humanized Candida and Nanobit Assays Expedite Discovery of BDF1 Bromodomain Inhibitors with Antifungal Potential Against Invasive Candida Infection Advanced Science 2024.