Potassium in PDB 8gae: HSP90 Provides Platform For Craf Dephosphorylation By PP5

All present enzymatic activity of HSP90 Provides Platform For Craf Dephosphorylation By PP5:
2.7.11.1; 3.1.3.16;

The structure of HSP90 Provides Platform For Craf Dephosphorylation By PP5 also contains other interesting chemical elements:

Manganese	(Mn)	2 atoms
Magnesium	(Mg)	2 atoms

The binding sites of Potassium atom in the HSP90 Provides Platform For Craf Dephosphorylation By PP5 (pdb code 8gae). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the HSP90 Provides Platform For Craf Dephosphorylation By PP5, PDB code: 8gae:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the HSP90 Provides Platform For Craf Dephosphorylation By PP5


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of HSP90 Provides Platform For Craf Dephosphorylation By PP5 within 5.0Å range: probe atom residue distance (Å) B Occ A:K801 b:119.2 occ:1.00 O A:GLY130 2.8 124.0 1.0 O A:ASN101 2.8 122.4 1.0 O A:THR104 2.9 122.9 1.0 O A:LYS107 3.1 127.0 1.0 OH A:TYR134 3.2 113.0 1.0 HE2 A:TYR134 3.2 113.0 1.0 H5'2 A:ADP803 3.2 119.3 1.0 H A:LYS107 3.6 127.0 1.0 H5'1 A:ADP803 3.7 119.3 1.0 CE2 A:TYR134 3.8 113.0 1.0 HH A:TYR134 3.8 113.0 1.0 C A:GLY130 3.9 124.0 1.0 CZ A:TYR134 3.9 113.0 1.0 C5' A:ADP803 3.9 119.3 1.0 HA2 A:GLY130 4.0 124.0 1.0 HA A:LEU102 4.0 117.5 1.0 C A:ASN101 4.0 122.4 1.0 HA A:ILE105 4.1 119.9 1.0 C A:THR104 4.1 122.9 1.0 O1A A:ADP803 4.1 119.3 1.0 C A:LYS107 4.2 127.0 1.0 H A:ALA106 4.2 125.9 1.0 HA3 A:GLY130 4.3 124.0 1.0 CA A:GLY130 4.3 124.0 1.0 N A:LYS107 4.4 127.0 1.0 HB3 A:LYS107 4.5 127.0 1.0 H A:THR104 4.5 122.9 1.0 HA A:ASN101 4.5 122.4 1.0 H4' A:ADP803 4.6 119.3 1.0 N A:ALA106 4.6 125.9 1.0 HA A:VAL131 4.7 120.8 1.0 HA A:SER108 4.8 128.1 1.0 CA A:ILE105 4.8 119.9 1.0 CA A:LEU102 4.8 117.5 1.0 N A:ILE105 4.8 119.9 1.0 HB A:THR104 4.8 122.9 1.0 CA A:LYS107 4.8 127.0 1.0 HB3 A:PHE133 4.9 111.0 1.0 N A:LEU102 4.9 117.5 1.0 C4' A:ADP803 4.9 119.3 1.0 CA A:ASN101 4.9 122.4 1.0 N A:THR104 4.9 122.9 1.0 HD23 A:LEU102 4.9 117.5 1.0 HB3 A:ASN101 4.9 122.4 1.0 N A:VAL131 5.0 120.8 1.0 O A:LEU102 5.0 117.5 1.0 C A:ILE105 5.0 119.9 1.0 O5' A:ADP803 5.0 119.3 1.0 PA A:ADP803 5.0 119.3 1.0

Potassium binding site 2 out of 2 in the HSP90 Provides Platform For Craf Dephosphorylation By PP5


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of HSP90 Provides Platform For Craf Dephosphorylation By PP5 within 5.0Å range: probe atom residue distance (Å) B Occ B:K801 b:122.8 occ:1.00 O B:ASN101 2.7 121.0 1.0 O B:GLY130 2.8 117.5 1.0 O B:LYS107 3.0 125.2 1.0 O B:THR104 3.1 120.0 1.0 HE2 B:TYR134 3.1 111.6 1.0 H5'1 B:ATP803 3.4 122.1 1.0 OH B:TYR134 3.4 111.6 1.0 H5'2 B:ATP803 3.6 122.1 1.0 CE2 B:TYR134 3.8 111.6 1.0 HA B:LEU102 3.9 120.0 1.0 C B:ASN101 3.9 121.0 1.0 C B:GLY130 4.0 117.5 1.0 C5' B:ATP803 4.0 122.1 1.0 CZ B:TYR134 4.0 111.6 1.0 O B:ILE105 4.0 123.0 1.0 H B:LYS107 4.1 125.2 1.0 C B:LYS107 4.1 125.2 1.0 HH B:TYR134 4.2 111.6 1.0 C B:THR104 4.3 120.0 1.0 N B:LYS107 4.3 125.2 1.0 H B:THR104 4.3 120.0 1.0 HB3 B:LYS107 4.3 125.2 1.0 C B:ILE105 4.4 123.0 1.0 HA B:ILE105 4.4 123.0 1.0 O1A B:ATP803 4.4 122.1 1.0 HA2 B:GLY130 4.4 117.5 1.0 HA B:ASN101 4.4 121.0 1.0 HG22 B:THR104 4.5 120.0 1.0 HA3 B:GLY130 4.5 117.5 1.0 H4' B:ATP803 4.5 122.1 1.0 HA B:VAL131 4.5 118.5 1.0 CA B:GLY130 4.6 117.5 1.0 CA B:LYS107 4.7 125.2 1.0 CA B:LEU102 4.7 120.0 1.0 HD11 B:LEU102 4.7 120.0 1.0 C B:ALA106 4.7 122.2 1.0 N B:LEU102 4.7 120.0 1.0 HA B:SER108 4.8 126.1 1.0 N B:ALA106 4.8 122.2 1.0 CA B:ASN101 4.8 121.0 1.0 CA B:ILE105 4.8 123.0 1.0 C4' B:ATP803 4.9 122.1 1.0 HB3 B:PHE133 4.9 109.8 1.0 CD2 B:TYR134 5.0 111.6 1.0

M.Jaime-Garza, D.A.Agard, C.A.Nowotny, C.Coutandin, F.Wang, M.Tabios. HSP90 Provides A Platform For Kinase Dephosphorylation By PP5 Nat Commun 2023.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-023-37659-7