Potassium in PDB 8fz7: Tpea Bound Closed Mthk-A88F Mutant in Nanodisc

The binding sites of Potassium atom in the Tpea Bound Closed Mthk-A88F Mutant in Nanodisc (pdb code 8fz7). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Tpea Bound Closed Mthk-A88F Mutant in Nanodisc, PDB code: 8fz7:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Tpea Bound Closed Mthk-A88F Mutant in Nanodisc


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Tpea Bound Closed Mthk-A88F Mutant in Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ A:K403 b:48.1 occ:1.00 OG1 A:THR59 3.1 56.9 1.0 OG1 E:THR59 3.1 57.0 1.0 OG1 C:THR59 3.1 56.6 1.0 OG1 G:THR59 3.1 56.6 1.0 O A:THR59 3.4 56.9 1.0 O C:THR59 3.5 56.6 1.0 O G:THR59 3.5 56.6 1.0 O E:THR59 3.5 57.0 1.0 C11 A:YQ1402 3.7 60.0 1.0 C16 A:YQ1402 3.7 60.0 1.0 CB A:THR59 3.8 56.9 1.0 CB G:THR59 3.8 56.6 1.0 CB C:THR59 3.8 56.6 1.0 CB E:THR59 3.8 57.0 1.0 K A:K404 3.9 57.2 1.0 N01 A:YQ1402 4.4 60.0 1.0 C A:THR59 4.4 56.9 1.0 C C:THR59 4.4 56.6 1.0 C E:THR59 4.4 57.0 1.0 C G:THR59 4.4 56.6 1.0 CA A:THR59 4.8 56.9 1.0 CA C:THR59 4.8 56.6 1.0 CA G:THR59 4.8 56.6 1.0 CA E:THR59 4.8 57.0 1.0 CG2 G:THR59 4.9 56.6 1.0 CG2 E:THR59 4.9 57.0 1.0 CG2 C:THR59 4.9 56.6 1.0 CG2 A:THR59 4.9 56.9 1.0 C02 A:YQ1402 5.0 60.0 1.0

Potassium binding site 2 out of 2 in the Tpea Bound Closed Mthk-A88F Mutant in Nanodisc


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Tpea Bound Closed Mthk-A88F Mutant in Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ A:K404 b:57.2 occ:1.00 O E:THR59 2.9 57.0 1.0 O A:THR59 2.9 56.9 1.0 O G:THR59 2.9 56.6 1.0 O C:THR59 2.9 56.6 1.0 O A:VAL60 3.2 58.2 1.0 O C:VAL60 3.3 58.2 1.0 O E:VAL60 3.3 58.3 1.0 O G:VAL60 3.3 58.3 1.0 K A:K403 3.9 48.1 1.0 C A:VAL60 3.9 58.2 1.0 C E:VAL60 3.9 58.3 1.0 C C:VAL60 3.9 58.2 1.0 C G:VAL60 3.9 58.3 1.0 C A:THR59 4.0 56.9 1.0 C E:THR59 4.0 57.0 1.0 C G:THR59 4.0 56.6 1.0 C C:THR59 4.0 56.6 1.0 CA A:VAL60 4.4 58.2 1.0 CA E:VAL60 4.4 58.3 1.0 CA C:VAL60 4.4 58.2 1.0 CA G:VAL60 4.4 58.3 1.0 N A:GLY61 4.6 65.0 1.0 N C:GLY61 4.7 65.1 1.0 N G:GLY61 4.7 64.9 1.0 N E:GLY61 4.7 65.0 1.0 N A:VAL60 4.7 58.2 1.0 N E:VAL60 4.7 58.3 1.0 N G:VAL60 4.7 58.3 1.0 N C:VAL60 4.7 58.2 1.0 CA A:GLY61 4.8 65.0 1.0 CA C:GLY61 4.9 65.1 1.0 CA G:GLY61 4.9 64.9 1.0 CA E:GLY61 4.9 65.0 1.0

C.Fan, E.Flood, N.Sukomon, S.Agarwal, T.W.Allen, C.M.Nimigean. Calcium-Gated Potassium Channel Blockade Via Membrane-Facing Fenestrations. Nat.Chem.Biol. 2023.
ISSN: ESSN 1552-4469
PubMed: 37653172
DOI: 10.1038/S41589-023-01406-2