Potassium in PDB 8e51: Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2

The structure of Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2, PDB code: 8e51 was solved by E.Scheib, C.R.Nisler, M.Sotomayor, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.60 / 2.59
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	75.816, 75.816, 242.68, 90, 90, 120
R / Rfree (%)	20.2 / 24.2

The structure of Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 also contains other interesting chemical elements:

Calcium

(Ca)

13 atoms

The binding sites of Potassium atom in the Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 (pdb code 8e51). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2, PDB code: 8e51:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:K307 b:89.2 occ:1.00 O B:GLY38 2.7 67.5 1.0 C B:GLY38 3.7 61.6 1.0 CA B:GLY38 4.3 55.9 1.0 N B:GLU39 4.7 60.3 1.0 CA B:GLU39 4.8 60.7 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Iridescent Shark Catfish Cadherin-23 EC1-2 and Protocadherin-15 EC1-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:K308 b:90.3 occ:1.00 O B:HOH402 2.0 68.0 1.0 O B:THR93 2.8 56.2 1.0 OD1 B:ASP92 2.8 62.1 1.0 O B:PHE12 2.8 60.4 1.0 OD2 C:ASP164 3.5 98.7 1.0 CG B:ASP92 3.8 69.4 1.0 C B:PHE12 3.8 60.5 1.0 C B:THR93 4.0 56.7 1.0 CA B:PHE12 4.1 57.9 1.0 OD2 B:ASP92 4.1 81.5 1.0 N B:THR93 4.3 58.8 1.0 CB B:PHE12 4.3 50.7 1.0 CA B:THR93 4.6 55.8 1.0 CG C:ASP164 4.7 98.8 1.0 CB B:THR93 4.7 57.3 1.0 CD1 B:PHE12 4.8 51.1 1.0 CB B:ASP92 5.0 60.9 1.0

C.R.Nisler, Y.Narui, E.Scheib, D.Choudhary, J.D.Bowman, H.Mandayam Bharathi, V.J.Lynch, M.Sotomayor. Interpreting the Evolutionary Echoes of A Protein Complex Essential For Inner-Ear Mechanosensation. Mol.Biol.Evol. 2023.
ISSN: ESSN 1537-1719
PubMed: 36911992
DOI: 10.1093/MOLBEV/MSAD057