Potassium in PDB 8dzv: Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide

The structure of Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide, PDB code: 8dzv was solved by P.J.Conroy, H.P.Law, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.72 / 1.20
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	45.8, 74.21, 75.43, 90, 90, 90
R / Rfree (%)	16.1 / 17.4

The binding sites of Potassium atom in the Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide (pdb code 8dzv). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide, PDB code: 8dzv:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:K301 b:7.6 occ:1.00 OG A:SER252 2.9 37.2 1.0 N A:SER252 3.4 13.2 1.0 O A:HOH760 3.5 26.0 1.0 CB A:SER252 4.0 25.9 1.0 CA A:SER251 4.1 10.1 1.0 CA A:SER252 4.2 18.4 1.0 C A:SER251 4.2 12.0 1.0 CB A:ALA216 4.2 11.2 1.0 CG A:PRO142 4.3 16.1 1.0 OG A:SER251 4.4 11.9 1.0 C A:SER252 4.7 22.8 1.0 CB A:SER251 4.9 8.9 1.0

Potassium binding site 2 out of 2 in the Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Chicken Anti-Cardiac Troponin I Antibody in Complex with Peptide within 5.0Å range: probe atom residue distance (Å) B Occ A:K302 b:1.7 occ:1.00 O A:HOH526 3.4 15.8 1.0 O A:HOH518 3.6 10.9 1.0 N A:TRP175 3.7 5.7 1.0 N A:PHE101 3.7 7.2 1.0 O A:HOH645 3.9 26.6 1.0 O A:HOH806 4.0 32.2 1.0 O A:HOH592 4.0 30.0 1.0 CA A:GLU174 4.1 6.7 1.0 CA A:ILE100 4.1 6.8 1.0 CD2 A:PHE101 4.2 6.9 1.0 CG A:GLU174 4.3 8.9 1.0 O A:HOH676 4.3 37.5 1.0 O A:LEU173 4.4 6.8 1.0 CB A:TRP175 4.4 6.7 1.0 C A:GLU174 4.4 5.6 1.0 C A:ILE100 4.4 5.4 1.0 CB A:PHE101 4.5 6.8 1.0 O A:PHE101 4.6 9.6 1.0 CA A:PHE101 4.7 6.3 1.0 CA A:TRP175 4.7 5.6 1.0 CB A:GLU174 4.7 6.3 1.0 CB A:ILE100 4.7 8.5 1.0 O A:THR99 4.8 7.3 1.0 O A:HOH737 4.8 33.1 1.0 CG A:PHE101 4.9 6.3 1.0

J.Islam, P.Conroy, C.Fercher, M.Kim, Z.Yaari, M.Jones, T.D.M.Bell, T.Caradoc-Davies, R.Law, J.Whisstock, D.Heller, S.Mahler, S.Corrie. Design of Polarity-Dependent Immunosensors Based on the Structural Analysis of Engineered Antibodies. Acs Chem.Biol. 2023.
ISSN: ESSN 1554-8937
PubMed: 37440171
DOI: 10.1021/ACSCHEMBIO.3C00303