Potassium in PDB 8dfl: Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation)
Potassium Binding Sites:
The binding sites of Potassium atom in the Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation)
(pdb code 8dfl). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 3 binding sites of Potassium where determined in the
Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation), PDB code: 8dfl:
Jump to Potassium binding site number:
1;
2;
3;
Potassium binding site 1 out
of 3 in 8dfl
Go back to
Potassium Binding Sites List in 8dfl
Potassium binding site 1 out
of 3 in the Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation)
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K901
b:30.0
occ:1.00
|
N
|
D:TYR447
|
4.3
|
78.0
|
1.0
|
N
|
C:TYR447
|
4.3
|
78.0
|
1.0
|
N
|
B:TYR447
|
4.3
|
78.0
|
1.0
|
N
|
A:TYR447
|
4.3
|
78.0
|
1.0
|
CA
|
D:GLY446
|
4.5
|
52.8
|
1.0
|
CA
|
A:GLY446
|
4.6
|
52.8
|
1.0
|
CA
|
C:GLY446
|
4.6
|
52.8
|
1.0
|
CA
|
B:GLY446
|
4.6
|
52.8
|
1.0
|
CB
|
D:TYR447
|
4.7
|
78.0
|
1.0
|
CB
|
C:TYR447
|
4.7
|
78.0
|
1.0
|
CB
|
B:TYR447
|
4.7
|
78.0
|
1.0
|
C
|
D:GLY446
|
4.8
|
52.8
|
1.0
|
CB
|
A:TYR447
|
4.8
|
78.0
|
1.0
|
C
|
C:GLY446
|
4.8
|
52.8
|
1.0
|
C
|
A:GLY446
|
4.8
|
52.8
|
1.0
|
C
|
B:GLY446
|
4.8
|
52.8
|
1.0
|
CA
|
D:TYR447
|
4.9
|
78.0
|
1.0
|
CA
|
C:TYR447
|
4.9
|
78.0
|
1.0
|
CA
|
B:TYR447
|
4.9
|
78.0
|
1.0
|
CA
|
A:TYR447
|
4.9
|
78.0
|
1.0
|
|
Potassium binding site 2 out
of 3 in 8dfl
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Potassium Binding Sites List in 8dfl
Potassium binding site 2 out
of 3 in the Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation)
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K902
b:30.0
occ:1.00
|
O
|
D:VAL445
|
2.1
|
43.5
|
1.0
|
O
|
B:VAL445
|
2.2
|
43.5
|
1.0
|
O
|
C:VAL445
|
2.2
|
43.5
|
1.0
|
O
|
A:VAL445
|
2.2
|
43.5
|
1.0
|
C
|
D:VAL445
|
3.4
|
43.5
|
1.0
|
C
|
B:VAL445
|
3.4
|
43.5
|
1.0
|
C
|
C:VAL445
|
3.4
|
43.5
|
1.0
|
C
|
A:VAL445
|
3.4
|
43.5
|
1.0
|
O
|
A:THR444
|
3.7
|
42.0
|
1.0
|
O
|
D:THR444
|
3.7
|
42.0
|
1.0
|
O
|
C:THR444
|
3.7
|
42.0
|
1.0
|
O
|
B:THR444
|
3.7
|
42.0
|
1.0
|
CA
|
D:GLY446
|
4.2
|
52.8
|
1.0
|
CA
|
D:VAL445
|
4.2
|
43.5
|
1.0
|
CA
|
B:GLY446
|
4.2
|
52.8
|
1.0
|
CA
|
C:GLY446
|
4.2
|
52.8
|
1.0
|
CA
|
B:VAL445
|
4.2
|
43.5
|
1.0
|
CA
|
C:VAL445
|
4.2
|
43.5
|
1.0
|
CA
|
A:VAL445
|
4.3
|
43.5
|
1.0
|
N
|
D:GLY446
|
4.3
|
52.8
|
1.0
|
CA
|
A:GLY446
|
4.3
|
52.8
|
1.0
|
N
|
B:GLY446
|
4.3
|
52.8
|
1.0
|
N
|
C:GLY446
|
4.3
|
52.8
|
1.0
|
N
|
A:GLY446
|
4.4
|
52.8
|
1.0
|
K
|
A:K903
|
4.4
|
30.0
|
1.0
|
C
|
D:THR444
|
4.5
|
42.0
|
1.0
|
C
|
A:THR444
|
4.5
|
42.0
|
1.0
|
C
|
C:THR444
|
4.5
|
42.0
|
1.0
|
C
|
B:THR444
|
4.5
|
42.0
|
1.0
|
N
|
D:VAL445
|
4.8
|
43.5
|
1.0
|
N
|
C:VAL445
|
4.8
|
43.5
|
1.0
|
N
|
B:VAL445
|
4.8
|
43.5
|
1.0
|
N
|
A:VAL445
|
4.8
|
43.5
|
1.0
|
|
Potassium binding site 3 out
of 3 in 8dfl
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Potassium Binding Sites List in 8dfl
Potassium binding site 3 out
of 3 in the Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation)
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 3 of Structure of Human KV1.3 with A0194009G09 Nanobodies (Alternate Conformation) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K903
b:30.0
occ:1.00
|
O
|
D:THR444
|
2.9
|
42.0
|
1.0
|
O
|
B:THR444
|
2.9
|
42.0
|
1.0
|
O
|
C:THR444
|
2.9
|
42.0
|
1.0
|
O
|
A:THR444
|
3.0
|
42.0
|
1.0
|
OG1
|
D:THR444
|
3.5
|
42.0
|
1.0
|
OG1
|
A:THR444
|
3.5
|
42.0
|
1.0
|
OG1
|
C:THR444
|
3.6
|
42.0
|
1.0
|
OG1
|
B:THR444
|
3.6
|
42.0
|
1.0
|
CB
|
D:THR444
|
3.9
|
42.0
|
1.0
|
CB
|
A:THR444
|
3.9
|
42.0
|
1.0
|
CB
|
C:THR444
|
3.9
|
42.0
|
1.0
|
CB
|
B:THR444
|
3.9
|
42.0
|
1.0
|
C
|
D:THR444
|
4.0
|
42.0
|
1.0
|
C
|
C:THR444
|
4.0
|
42.0
|
1.0
|
C
|
B:THR444
|
4.0
|
42.0
|
1.0
|
C
|
A:THR444
|
4.1
|
42.0
|
1.0
|
K
|
A:K902
|
4.4
|
30.0
|
1.0
|
CA
|
D:THR444
|
4.6
|
42.0
|
1.0
|
CA
|
C:THR444
|
4.6
|
42.0
|
1.0
|
CA
|
B:THR444
|
4.6
|
42.0
|
1.0
|
CA
|
A:THR444
|
4.6
|
42.0
|
1.0
|
|
Reference:
P.Selvakumar,
A.I.Fernandez-Marino,
N.Khanra,
C.He,
A.J.Paquette,
B.Wang,
R.Huang,
V.V.Smider,
W.J.Rice,
K.J.Swartz,
J.R.Meyerson.
Structures of the T Cell Potassium Channel KV1.3 with Immunoglobulin Modulators Nat Commun V. 13 3854 2022.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-022-31285-5
Page generated: Wed Apr 5 10:42:52 2023
|