Potassium in PDB 8cgv: Tiamulin Bound to the 50S Subunit

The structure of Tiamulin Bound to the 50S Subunit also contains other interesting chemical elements:

Magnesium	(Mg)	219 atoms
Zinc	(Zn)	1 atom
Fluorine	(F)	2 atoms

Pages:

>>> Page 1 <<< Page 2, Binding sites: 11 - 20; Page 3, Binding sites: 21 - 30; Page 4, Binding sites: 31 - 40; Page 5, Binding sites: 41 - 50; Page 6, Binding sites: 51 - 60; Page 7, Binding sites: 61 - 70; Page 8, Binding sites: 71 - 80; Page 9, Binding sites: 81 - 83;

Binding sites:

The binding sites of Potassium atom in the Tiamulin Bound to the 50S Subunit (pdb code 8cgv). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 83 binding sites of Potassium where determined in the Tiamulin Bound to the 50S Subunit, PDB code: 8cgv:
Jump to Potassium binding site number: 1; 2; 3; 4; 5; 6; 7; 8; 9; 10;

Potassium binding site 1 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3184 b:19.9 occ:1.00 O6 a:G2447 2.7 19.5 1.0 O6 a:G2061 2.7 18.8 1.0 O a:HOH8199 2.8 23.0 1.0 N7 a:G2447 2.8 16.9 1.0 O4' a:C2501 2.9 19.2 1.0 O2 a:PSU2504 3.0 21.9 1.0 O2 a:C2501 3.2 19.0 1.0 C6 a:G2447 3.3 17.8 1.0 N7 a:G2061 3.3 20.4 1.0 C5 a:G2447 3.4 17.0 1.0 C6 a:G2061 3.5 18.2 1.0 C2 a:C2501 3.6 17.1 1.0 C1' a:C2501 3.7 19.3 1.0 C5 a:G2061 3.7 19.3 1.0 C2 a:PSU2504 3.8 19.8 1.0 C4' a:C2501 3.9 19.2 1.0 N1 a:PSU2504 3.9 20.6 1.0 N1 a:C2501 3.9 17.6 1.0 N6 a:A2451 3.9 17.7 1.0 C8 a:G2447 4.0 16.5 1.0 C5' a:C2501 4.2 19.1 1.0 N3 a:C2501 4.5 17.4 1.0 C8 a:G2061 4.5 20.8 1.0 C17 a:MUL3003 4.6 24.5 1.0 N1 a:G2447 4.6 17.4 1.0 C4 a:G2447 4.7 16.4 1.0 C2' a:U2500 4.7 18.5 1.0 O5' a:C2501 4.8 18.4 1.0 N1 a:G2061 4.8 18.3 1.0 C6 a:C2501 4.9 17.2 1.0 N4 a:C2452 5.0 20.4 1.0

Potassium binding site 2 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3185 b:23.0 occ:1.00 O a:HOH8234 2.7 31.5 1.0 O3' a:G1022 2.7 24.5 1.0 O2' a:G1022 2.8 24.1 1.0 N7 a:G1024 2.8 20.7 1.0 OP2 a:U1023 2.8 23.9 1.0 N3 a:G1025 2.9 21.1 1.0 O6 a:G1024 3.0 21.0 1.0 C2 a:G1025 3.2 20.8 1.0 O2' a:G1025 3.3 21.4 1.0 P a:U1023 3.4 23.7 1.0 C4 a:G1025 3.5 20.5 1.0 N2 a:G1025 3.5 21.3 1.0 C5 a:G1024 3.5 20.2 1.0 C6 a:G1024 3.6 19.7 1.0 C2' a:G1022 3.8 24.9 1.0 C3' a:G1022 3.8 25.2 1.0 C8 a:G1024 4.0 20.0 1.0 MG a:MG3120 4.0 21.4 1.0 O a:HOH5518 4.0 23.8 1.0 N9 a:G1025 4.0 21.3 1.0 N1 a:G1025 4.1 20.9 1.0 C2' a:G1025 4.1 22.8 1.0 C1' a:G1022 4.2 24.1 1.0 C1' a:G1025 4.3 23.0 1.0 C5 a:G1025 4.3 21.6 1.0 OP2 a:C1135 4.4 27.8 1.0 O5' a:U1023 4.4 24.5 1.0 OP1 a:U1023 4.5 25.4 1.0 C6 a:G1025 4.7 20.1 1.0 O a:HOH5489 4.7 50.6 1.0 OP2 a:G1024 4.8 24.4 1.0 C4 a:G1024 4.8 19.4 1.0 N1 a:G1024 5.0 20.0 1.0 C4' a:G1022 5.0 25.3 1.0

Potassium binding site 3 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3186 b:24.8 occ:1.00 O a:HOH8566 2.6 40.8 1.0 OP2 a:A195 2.7 20.0 1.0 O3' a:A196 2.8 18.0 1.0 O2' a:A196 2.9 19.6 1.0 O a:HOH6189 2.9 39.1 1.0 O a:HOH7063 2.9 27.6 1.0 OP1 a:A197 3.1 17.2 1.0 O a:HOH8228 3.4 16.4 1.0 P a:A197 3.5 15.6 1.0 O a:HOH4783 3.7 16.3 1.0 C5' a:A197 3.7 17.0 1.0 C2' a:A196 3.8 18.6 1.0 C3' a:A196 3.9 18.5 1.0 P a:A195 4.0 18.6 1.0 O5' a:A197 4.1 17.1 1.0 C1' a:A196 4.1 17.9 1.0 MG a:MG3097 4.2 14.5 1.0 OP1 a:A195 4.4 21.6 1.0 OP2 a:G194 4.5 22.6 1.0 O a:HOH8446 4.6 35.7 1.0 O a:HOH4178 4.6 35.2 1.0 O5' a:A195 4.7 19.1 1.0 OP1 a:G194 4.7 23.4 1.0 O a:HOH6518 4.7 37.0 1.0 C4' a:A196 4.8 19.9 1.0 OP2 a:A197 4.9 17.8 1.0 P a:G194 4.9 20.4 1.0

Potassium binding site 4 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3187 b:26.1 occ:1.00 O a:HOH4924 2.7 30.6 1.0 O6 a:G375 2.7 26.7 1.0 O6 a:G376 2.8 23.2 1.0 O a:HOH4370 2.8 27.2 1.0 O a:HOH4036 2.9 28.2 1.0 O a:HOH6336 2.9 31.1 1.0 O4 a:U399 3.0 26.6 1.0 O a:HOH8915 3.4 33.8 1.0 C6 a:G376 3.7 22.4 1.0 C4 a:U399 3.8 25.3 1.0 C6 a:G375 3.8 26.0 1.0 MG a:MG3134 3.8 34.2 1.0 N3 a:U399 3.8 24.9 1.0 N4 a:C398 4.0 22.5 1.0 N7 a:G376 4.1 25.2 1.0 N7 a:G375 4.2 26.7 1.0 N2 a:G400 4.2 26.3 1.0 C5 a:G376 4.3 24.9 1.0 O a:HOH6280 4.3 26.1 1.0 OP2 a:A374 4.3 31.5 1.0 C5 a:G375 4.3 26.5 1.0 C2 a:G400 4.5 26.3 1.0 OP2 a:U373 4.7 33.3 1.0 N1 a:G400 4.7 26.7 1.0 N1 a:G376 4.9 24.0 1.0 O w:HOH114 4.9 35.8 1.0 N1 a:G375 4.9 26.5 1.0 C2 a:U399 5.0 26.2 1.0

Potassium binding site 5 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 5 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3188 b:31.0 occ:1.00 O a:HOH3936 2.6 36.8 1.0 OP1 a:U2506 2.6 27.3 1.0 N3 a:A2572 2.9 22.6 1.0 OP2 a:C2573 2.9 23.9 1.0 O a:HOH3834 3.0 32.0 1.0 O2' a:A2572 3.0 18.0 1.0 O4' a:A2453 3.4 19.4 1.0 C2 a:A2572 3.6 23.2 1.0 O3' a:A2572 3.7 19.8 1.0 O a:HOH5277 3.8 31.5 1.0 C1' a:A2572 3.8 17.3 1.0 C4 a:A2572 3.9 19.0 1.0 P a:C2573 3.9 21.1 1.0 C2' a:A2572 3.9 17.3 1.0 C1' a:A2453 3.9 18.8 1.0 C4' a:A2453 4.0 19.2 1.0 P a:U2506 4.0 24.0 1.0 O a:HOH3450 4.1 39.6 1.0 O2' a:A2453 4.2 19.6 1.0 N9 a:A2572 4.3 18.2 1.0 O5' a:U2506 4.3 27.0 1.0 O2' a:C2452 4.5 24.5 1.0 C3' a:A2572 4.5 18.0 1.0 C2' a:A2453 4.6 19.4 1.0 O1 a:MUL3003 4.8 25.1 1.0 OP1 a:C2573 4.8 22.7 1.0 C5' a:A2453 4.8 20.3 1.0 C5' a:U2506 4.8 33.2 1.0 O a:HOH5771 4.9 39.9 1.0 N1 a:A2572 4.9 23.6 1.0 O3' a:G2505 5.0 24.0 1.0

Potassium binding site 6 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 6 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3189 b:36.7 occ:1.00 O a:HOH7161 2.7 46.0 1.0 O a:HOH7274 2.9 29.5 1.0 O a:HOH5683 2.9 34.2 1.0 O6 a:G2838 2.9 24.8 1.0 O6 a:G2839 3.0 26.9 1.0 N7 a:G2838 3.0 24.3 1.0 O4 a:U2878 3.2 29.2 1.0 C6 a:G2838 3.6 22.8 1.0 C5 a:G2838 3.6 23.8 1.0 C6 a:G2839 3.7 23.2 1.0 N7 a:G2839 4.0 23.4 1.0 C4 a:U2878 4.1 28.0 1.0 C8 a:G2838 4.1 24.0 1.0 C5 a:G2839 4.1 23.4 1.0 N3 a:U2878 4.2 28.1 1.0 C2 a:A2835 4.2 27.3 1.0 N7 a:A2837 4.2 22.1 1.0 N3 a:A2835 4.2 27.2 1.0 N6 a:A2837 4.3 19.5 1.0 C5 a:A2837 4.4 21.6 1.0 C6 a:A2837 4.5 20.7 1.0 O a:HOH6124 4.6 39.2 1.0 O6 a:G2877 4.6 27.8 1.0 O a:HOH4857 4.6 41.7 1.0 N1 a:G2839 4.8 22.7 1.0 C8 a:A2837 4.9 21.1 1.0 C4 a:G2838 4.9 22.7 1.0 N1 a:G2838 4.9 22.7 1.0

Potassium binding site 7 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 7 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3190 b:31.2 occ:1.00 O6 a:G559 2.8 21.4 1.0 O4 a:U534 2.8 22.3 1.0 O6 a:G533 2.9 20.3 1.0 O a:HOH6592 2.9 38.0 1.0 O a:HOH3387 2.9 27.3 1.0 O4 a:U558 3.0 25.1 1.0 O6 a:G535 3.5 21.4 1.0 C4 a:U558 3.5 23.8 1.0 C4 a:U534 3.7 20.0 1.0 N3 a:U558 3.7 22.7 1.0 N3 a:U534 3.7 20.7 1.0 N4 a:C560 3.8 19.3 1.0 C6 a:G533 3.8 18.6 1.0 C6 a:G559 3.9 20.3 1.0 N7 a:G559 4.3 21.9 1.0 O a:HOH6026 4.3 40.6 1.0 C6 a:G535 4.3 21.0 1.0 C5 a:G559 4.5 21.4 1.0 O a:HOH5533 4.5 49.7 1.0 C5 a:U558 4.6 24.9 1.0 C5 a:G533 4.6 19.3 1.0 C4 a:C560 4.6 19.4 1.0 N1 a:G533 4.7 18.2 1.0 N7 a:G533 4.8 19.0 1.0 O a:HOH8406 4.8 41.0 1.0 C2 a:U558 4.8 22.8 1.0 N1 a:G535 5.0 20.9 1.0

Potassium binding site 8 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 8 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3191 b:32.5 occ:1.00 O4 a:U1242 2.7 26.8 1.0 O4 a:U1203 2.7 30.0 1.0 O6 a:G1202 2.8 25.4 1.0 OP2 a:A1241 2.8 35.8 1.0 O a:HOH5843 2.9 44.4 1.0 O a:HOH7282 3.0 29.0 1.0 N6 a:A1204 3.4 27.6 1.0 C4 a:U1203 3.6 27.7 1.0 N3 a:U1203 3.7 27.5 1.0 C4 a:U1242 3.8 26.8 1.0 C6 a:G1202 3.8 25.0 1.0 O a:HOH4468 3.9 40.7 1.0 N4 a:C1243 4.0 26.5 1.0 C6 a:A1204 4.0 26.8 1.0 P a:A1241 4.0 36.4 1.0 MG a:MG3156 4.1 34.7 1.0 N1 a:A1204 4.2 29.5 1.0 C5 a:U1242 4.3 29.0 1.0 O a:HOH3431 4.3 29.4 1.0 OP1 a:A1241 4.3 39.8 1.0 N7 a:G1202 4.4 25.1 1.0 C5 a:G1202 4.5 24.1 1.0 O a:HOH8795 4.7 41.1 1.0 O4 a:U1201 4.8 24.2 1.0 N3 a:U1242 4.9 27.7 1.0 N1 a:G1202 4.9 25.2 1.0 O5' a:A1241 4.9 35.3 1.0 C5 a:U1203 5.0 28.7 1.0 C5 a:A1204 5.0 27.4 1.0

Potassium binding site 9 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 9 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3192 b:28.1 occ:1.00 O6 a:G1288 2.6 24.6 1.0 O a:HOH8675 2.6 37.8 1.0 O2 a:U1326 2.6 23.4 1.0 O m:GLY105 2.8 25.2 1.0 O a:HOH6848 2.9 26.6 1.0 O4' a:A1327 3.0 23.3 1.0 O a:HOH8581 3.2 50.8 1.0 N6 a:A1287 3.5 21.8 1.0 O2' a:U1326 3.5 22.8 1.0 C1' a:A1327 3.6 23.8 1.0 C m:GLY105 3.8 24.7 1.0 C6 a:G1288 3.8 21.3 1.0 C2 a:U1326 3.8 21.0 1.0 C2' a:U1326 3.9 21.6 1.0 O a:HOH7498 4.0 35.0 1.0 CA m:GLY105 4.1 25.1 1.0 C4' a:A1327 4.1 24.1 1.0 N9 a:A1327 4.1 21.2 1.0 C1' a:U1326 4.4 20.4 1.0 C8 a:A1327 4.5 21.3 1.0 C6 a:A1287 4.5 21.7 1.0 N1 a:G1288 4.6 21.2 1.0 C5' a:A1327 4.7 23.0 1.0 N1 a:U1326 4.7 21.0 1.0 N3 a:U1326 4.8 21.1 1.0 C2' a:A1327 4.9 24.4 1.0 C5 a:G1288 4.9 21.1 1.0 C4 a:A1327 4.9 21.4 1.0

Potassium binding site 10 out of 83 in the Tiamulin Bound to the 50S Subunit


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 10 of Tiamulin Bound to the 50S Subunit within 5.0Å range: probe atom residue distance (Å) B Occ a:K3193 b:29.6 occ:1.00 O4 a:U1397 2.7 23.6 1.0 O a:HOH8535 2.8 40.8 1.0 O2' a:U1602 2.9 23.1 1.0 O2' a:U1394 3.0 25.1 1.0 O5' a:A1395 3.0 26.4 1.0 O3' a:U1602 3.0 22.8 1.0 OP1 a:A1395 3.0 25.2 1.0 O3' a:U1394 3.2 24.8 1.0 OP1 a:A1603 3.2 24.0 1.0 P a:A1395 3.3 23.5 1.0 C5' a:A1603 3.6 22.9 1.0 P a:A1603 3.7 21.5 1.0 C4 a:U1397 3.8 21.1 1.0 C2' a:U1602 3.9 22.9 1.0 C2' a:U1394 3.9 25.6 1.0 O a:HOH4373 4.0 44.7 1.0 C3' a:U1602 4.1 23.2 1.0 C3' a:U1394 4.1 24.4 1.0 O5' a:A1603 4.2 22.9 1.0 C5' a:A1395 4.2 27.8 1.0 MG a:MG3044 4.2 20.9 1.0 OP1 a:G1341 4.2 22.6 1.0 C1' a:U1602 4.3 22.2 1.0 N3 a:U1397 4.3 21.2 1.0 O a:HOH6294 4.4 27.0 1.0 OP2 a:G1341 4.5 22.8 1.0 C4' a:A1395 4.6 27.9 1.0 O2 a:U1602 4.6 20.8 1.0 P a:G1341 4.8 20.6 1.0 OP2 a:A1395 4.8 26.2 1.0 C5 a:U1397 4.9 21.2 1.0 C4' a:U1394 4.9 25.6 1.0 C4' a:A1603 5.0 22.6 1.0

H.Paternoga, C.Crowe-Mcauliffe, L.V.Bock, T.O.Koller, M.Morici, B.Beckert, A.G.Myasnikov, H.Grubmueller, J.Novacek, D.N.Wilson. Structural Conservation of Antibiotic Interaction with Ribosomes To Be Published.