Atomistry » Potassium » PDB 8bm1-8cfv » 8cfb
Atomistry »
  Potassium »
    PDB 8bm1-8cfv »
      8cfb »

Potassium in PDB 8cfb: Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02

Enzymatic activity of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02

All present enzymatic activity of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02:
3.3.1.1;

Protein crystallography data

The structure of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02, PDB code: 8cfb was solved by P.H.Malecki, M.Gawel, M.Stepniewska, K.Brzezinski, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 32.64 / 2.07
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 175.97, 103.68, 109.2, 90, 99.99, 90
R / Rfree (%) 23.5 / 27.1

Other elements in 8cfb:

The structure of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 also contains other interesting chemical elements:

Fluorine (F) 2 atoms

Potassium Binding Sites:

The binding sites of Potassium atom in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 (pdb code 8cfb). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02, PDB code: 8cfb:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 8cfb

Go back to Potassium Binding Sites List in 8cfb
Potassium binding site 1 out of 4 in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K504

b:40.6
occ:1.00
 O A:HIS382 2.7 39.0 1.0
O A:THR380 2.8 42.8 1.0
OG1 A:THR380 2.8 41.8 1.0
O A:HOH642 2.8 36.0 1.0
O A:HOH651 3.0 38.0 1.0
O B:HOH658 3.0 36.6 1.0
OE1 A:GLN65 3.1 41.3 1.0
NE2 A:GLN65 3.4 36.8 1.0
CD A:GLN65 3.5 40.1 1.0
CB A:THR380 3.5 43.2 1.0
C A:HIS382 3.6 42.1 1.0
C A:THR380 3.6 38.2 1.0
O A:GLY381 3.8 35.6 1.0
CA A:PRO383 4.0 37.2 1.0
C A:GLY381 4.1 40.8 1.0
N A:PRO383 4.2 43.1 1.0
O A:HOH736 4.2 43.1 1.0
N6 A:ADE502 4.2 38.7 1.0
CA A:THR380 4.2 40.5 1.0
CB B:ASP216 4.3 42.5 1.0
N A:HIS382 4.5 39.6 1.0
N A:GLY381 4.5 39.6 1.0
CG B:ASP216 4.6 43.1 1.0
C A:PRO383 4.6 39.8 1.0
CG A:GLN65 4.6 43.7 1.0
OD1 B:ASP216 4.7 42.6 1.0
CA A:HIS382 4.7 39.8 1.0
CA A:GLY381 4.7 42.0 1.0
OE1 A:GLN91 4.8 42.0 1.0
O A:HOH737 4.8 42.9 1.0
N A:SER384 4.8 41.6 1.0
CG2 A:THR380 4.8 37.5 1.0
O B:ASP216 4.9 41.6 1.0

Potassium binding site 2 out of 4 in 8cfb

Go back to Potassium Binding Sites List in 8cfb
Potassium binding site 2 out of 4 in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K503

b:48.5
occ:1.00
 O B:HOH659 2.7 45.7 1.0
O B:HIS382 2.8 50.0 1.0
O B:THR380 2.8 57.5 1.0
OG1 B:THR380 2.9 46.6 1.0
O B:HOH667 3.0 45.0 1.0
O A:HOH658 3.2 49.3 1.0
OE1 B:GLN65 3.3 57.3 1.0
NE2 B:GLN65 3.5 50.9 1.0
CD B:GLN65 3.5 57.4 1.0
C B:HIS382 3.6 49.5 1.0
CB B:THR380 3.6 48.9 1.0
C B:THR380 3.6 55.5 1.0
O B:GLY381 3.8 51.7 1.0
CA B:PRO383 3.9 48.1 1.0
C B:GLY381 4.0 52.8 1.0
N B:PRO383 4.0 43.9 1.0
N6 B:ADE502 4.1 59.6 1.0
CA B:THR380 4.3 56.0 1.0
CB A:ASP216 4.3 44.7 1.0
N B:HIS382 4.4 52.8 1.0
N B:GLY381 4.5 53.7 1.0
CG A:ASP216 4.6 49.4 1.0
C B:PRO383 4.6 51.7 1.0
CA B:HIS382 4.6 53.1 1.0
O B:HOH681 4.6 50.6 1.0
OD1 A:ASP216 4.7 52.6 1.0
CG B:GLN65 4.7 53.5 1.0
CA B:GLY381 4.7 53.4 1.0
N B:SER384 4.8 53.3 1.0
CG2 B:THR380 4.9 47.9 1.0
O A:ASP216 4.9 48.4 1.0
O B:HOH629 5.0 52.6 1.0

Potassium binding site 3 out of 4 in 8cfb

Go back to Potassium Binding Sites List in 8cfb
Potassium binding site 3 out of 4 in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 within 5.0Å range:
probe atom residue distance (Å) B Occ
C:K503

b:64.5
occ:1.00
 O C:HIS382 2.8 85.6 1.0
OG1 C:THR380 2.8 85.7 1.0
O C:THR380 2.8 83.2 1.0
OE1 C:GLN65 3.1 85.7 1.0
NE2 C:GLN65 3.3 84.9 1.0
CD C:GLN65 3.3 85.2 1.0
CB C:THR380 3.4 82.6 1.0
C C:THR380 3.6 82.7 1.0
C C:HIS382 3.7 79.1 1.0
N6 C:ADE502 3.9 79.9 1.0
O C:GLY381 4.0 78.9 1.0
CA C:PRO383 4.0 79.1 1.0
CA C:THR380 4.2 83.1 1.0
C C:GLY381 4.2 81.8 1.0
N C:PRO383 4.2 77.6 1.0
CB D:ASP216 4.4 73.8 1.0
N C:HIS382 4.5 80.3 1.0
CG C:GLN65 4.5 85.1 1.0
CG D:ASP216 4.6 78.3 1.0
N C:GLY381 4.6 82.0 1.0
C C:PRO383 4.7 80.0 1.0
CA C:HIS382 4.7 79.0 1.0
OD1 D:ASP216 4.7 79.5 1.0
CG2 C:THR380 4.7 82.9 1.0
CA C:GLY381 4.8 81.7 1.0
OE1 C:GLN91 4.9 87.9 1.0
N C:SER384 4.9 79.3 1.0
O D:ASP216 5.0 70.7 1.0

Potassium binding site 4 out of 4 in 8cfb

Go back to Potassium Binding Sites List in 8cfb
Potassium binding site 4 out of 4 in the Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 within 5.0Å range:
probe atom residue distance (Å) B Occ
D:K503

b:54.5
occ:1.00
 O D:HIS382 2.7 70.1 1.0
O D:THR380 2.8 80.0 1.0
O D:HOH628 2.9 69.9 1.0
OG1 D:THR380 3.1 85.9 1.0
NE2 D:GLN65 3.2 79.7 1.0
OE1 D:GLN65 3.3 79.9 1.0
CD D:GLN65 3.5 79.8 1.0
CB D:THR380 3.6 77.7 1.0
C D:HIS382 3.7 69.1 1.0
C D:THR380 3.7 75.8 1.0
N6 D:ADE502 3.9 64.6 1.0
O D:GLY381 4.0 68.0 1.0
CA D:PRO383 4.1 69.7 1.0
C D:GLY381 4.2 67.9 1.0
N D:PRO383 4.3 69.2 1.0
CA D:THR380 4.3 73.9 1.0
CB C:ASP216 4.4 76.6 1.0
N D:HIS382 4.5 70.4 1.0
C D:PRO383 4.6 70.5 1.0
CG C:ASP216 4.6 74.1 1.0
N D:GLY381 4.7 70.1 1.0
CG D:GLN65 4.7 79.7 1.0
N D:SER384 4.7 65.4 1.0
CA D:HIS382 4.7 66.5 1.0
OD2 C:ASP216 4.8 76.1 1.0
CA D:GLY381 4.8 73.2 1.0
CG2 D:THR380 4.9 76.8 1.0
OE1 D:GLN91 4.9 81.6 1.0

Reference:

P.H.Malecki, M.Gawel, M.Stepniewska, K.Brzezinski. Crystal Structure of S-Adenosyl-L-Homocysteine Hydrolase From P. Aeruginosa in Complex with F2X-Entry Library Fragment D02 To Be Published.
Page generated: Mon Aug 12 22:23:54 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy