Potassium in PDB 8bb5: Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker

The structure of Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker, PDB code: 8bb5 was solved by A.Kraemer, A.Doelle, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.20 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	48.12, 86.689, 196.6, 90, 90, 90
R / Rfree (%)	20 / 24.8

The structure of Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker also contains other interesting chemical elements:

Fluorine

(F)

3 atoms

The binding sites of Potassium atom in the Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker (pdb code 8bb5). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker, PDB code: 8bb5:

Potassium binding site 1 out of 1 in the Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker within 5.0Å range: probe atom residue distance (Å) B Occ C:K304 b:30.0 occ:1.00 O C:HOH483 2.6 29.6 1.0 O D:HOH504 2.7 42.6 1.0 O2 C:Q43302 2.8 22.0 1.0 O D:HOH583 2.8 23.8 1.0 OH C:TYR112 2.8 27.6 1.0 O C:HOH494 3.0 30.0 1.0 N D:SCN402 3.6 48.6 1.0 CZ C:TYR112 3.8 27.8 1.0 C14 C:Q43302 3.9 25.9 1.0 CE1 C:TYR112 4.0 27.3 1.0 N3 C:Q43302 4.2 24.5 1.0 N1 C:Q43302 4.4 26.2 1.0 O C:HOH457 4.5 28.6 1.0 C9 C:Q43302 4.5 27.1 1.0 C51 C:Q43302 4.6 29.0 1.0 C15 C:Q43302 4.7 25.9 1.0 C D:SCN402 4.7 57.9 1.0 C10 C:Q43302 4.8 25.7 1.0 O C:HOH428 4.8 46.8 1.0 O C:HOH466 4.8 31.8 1.0 N2 C:Q43302 4.9 25.4 1.0 C16 C:Q43302 5.0 27.6 1.0

A.Kraemer, A.Doelle, S.Knapp, Structural Genomics Consortium (Sgc). Structure of Human WDR5 and Pvhl:Elonginc:Elonginb Bound to Protac with Aryl Linker To Be Published.