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Potassium in PDB 7zkn: X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
Enzymatic activity of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
All present enzymatic activity of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma:
3.4.21.5;
3.4.21.5;
Protein crystallography data
The structure of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma, PDB code: 7zkn
was solved by
R.Troisi,
F.Sica,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 68.13 / 3.03 |
| Space group | P 1 21 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 76.62, 114.86, 83.44, 90, 117.25, 90 |
| R / Rfree (%) | 20.1 / 24.3 |
Potassium Binding Sites:
The binding sites of Potassium atom in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
(pdb code 7zkn). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma, PDB code: 7zkn:
Jump to Potassium binding site number: 1; 2; 3; 4;
In total 4 binding sites of Potassium where determined in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma, PDB code: 7zkn:
Jump to Potassium binding site number: 1; 2; 3; 4;
Potassium binding site 1 out of 4 in 7zkn
Go back to
Potassium Binding Sites List in 7zkn
Potassium binding site 1 out
of 4 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma within 5.0Å range:
|
Potassium binding site 2 out of 4 in 7zkn
Go back to
Potassium Binding Sites List in 7zkn
Potassium binding site 2 out
of 4 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 2 of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma within 5.0Å range:
|
Potassium binding site 3 out of 4 in 7zkn
Go back to
Potassium Binding Sites List in 7zkn
Potassium binding site 3 out
of 4 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 3 of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma within 5.0Å range:
|
Potassium binding site 4 out of 4 in 7zkn
Go back to
Potassium Binding Sites List in 7zkn
Potassium binding site 4 out
of 4 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 4 of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Gamma within 5.0Å range:
|
Reference:
R.Troisi,
C.Riccardi,
K.Perez De Carvasal,
M.Smietana,
F.Morvan,
P.Del Vecchio,
D.Montesarchio,
F.Sica.
A Terminal Functionalization Strategy Reveals Unusual Binding Abilities of Anti-Thrombin Anticoagulant Aptamers. Mol Ther Nucleic Acids V. 30 585 2022.
ISSN: ISSN 2162-2531
PubMed: 36457701
DOI: 10.1016/J.OMTN.2022.11.007
Page generated: Mon Aug 12 21:50:12 2024
ISSN: ISSN 2162-2531
PubMed: 36457701
DOI: 10.1016/J.OMTN.2022.11.007
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