Potassium in PDB 7zkm: X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta
Enzymatic activity of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta
All present enzymatic activity of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta:
3.4.21.5;
3.4.21.5;
Protein crystallography data
The structure of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta, PDB code: 7zkm
was solved by
R.Troisi,
F.Sica,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 59.10 / 2.00 |
| Space group | P 31 2 1 |
| Cell size a, b, c (Å), α, β, γ (°) | 76.6, 76.6, 129.38, 90, 90, 120 |
| R / Rfree (%) | 22.6 / 25.2 |
Other elements in 7zkm:
The structure of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta also contains other interesting chemical elements:
| Sodium | (Na) | 1 atom |
Potassium Binding Sites:
The binding sites of Potassium atom in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta
(pdb code 7zkm). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta, PDB code: 7zkm:
Jump to Potassium binding site number: 1; 2;
In total 2 binding sites of Potassium where determined in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta, PDB code: 7zkm:
Jump to Potassium binding site number: 1; 2;
Potassium binding site 1 out of 2 in 7zkm
Go back to
Potassium Binding Sites List in 7zkm
Potassium binding site 1 out
of 2 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 1 of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta within 5.0Å range:
|
Potassium binding site 2 out of 2 in 7zkm
Go back to
Potassium Binding Sites List in 7zkm
Potassium binding site 2 out
of 2 in the X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Potassium with other atoms in the K binding
site number 2 of X-Ray Structure of the Complex Between Human Alpha Thrombin and A Pseudo-Cyclic Thrombin Binding Aptamer (Tba-Nnp/Ddp) - Crystal Form Beta within 5.0Å range:
|
Reference:
R.Troisi,
C.Riccardi,
K.Perez De Carvasal,
M.Smietana,
F.Morvan,
P.Del Vecchio,
D.Montesarchio,
F.Sica.
A Terminal Functionalization Strategy Reveals Unusual Binding Abilities of Anti-Thrombin Anticoagulant Aptamers. Mol Ther Nucleic Acids V. 30 585 2022.
ISSN: ISSN 2162-2531
PubMed: 36457701
DOI: 10.1016/J.OMTN.2022.11.007
Page generated: Wed Apr 5 10:31:05 2023
ISSN: ISSN 2162-2531
PubMed: 36457701
DOI: 10.1016/J.OMTN.2022.11.007
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