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Potassium in PDB 7ukg: Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region

Potassium Binding Sites:

The binding sites of Potassium atom in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region (pdb code 7ukg). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region, PDB code: 7ukg:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 7ukg

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Potassium binding site 1 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K601

b:24.0
occ:1.00
 OG1 A:THR370 3.0 22.4 1.0
OG1 D:THR370 3.0 22.3 1.0
OG1 C:THR370 3.0 22.3 1.0
OG1 B:THR370 3.0 22.4 1.0
O D:THR370 3.0 22.3 1.0
O C:THR370 3.0 22.3 1.0
O B:THR370 3.0 22.4 1.0
O A:THR370 3.1 22.4 1.0
K A:K602 3.4 17.7 1.0
CB A:THR370 3.7 22.4 1.0
CB D:THR370 3.7 22.3 1.0
CB C:THR370 3.7 22.3 1.0
CB B:THR370 3.7 22.4 1.0
C D:THR370 4.0 22.3 1.0
C C:THR370 4.0 22.3 1.0
C B:THR370 4.0 22.4 1.0
C A:THR370 4.0 22.4 1.0
CA D:THR370 4.5 22.3 1.0
CA C:THR370 4.5 22.3 1.0
CA B:THR370 4.5 22.4 1.0
CA A:THR370 4.5 22.4 1.0
O A:THR369 4.8 23.1 1.0
O D:THR369 4.8 23.0 1.0
O C:THR369 4.8 22.9 1.0
O B:THR369 4.8 23.1 1.0
CG2 A:THR370 4.8 22.4 1.0
CG2 D:THR370 4.9 22.3 1.0
CG2 C:THR370 4.9 22.3 1.0
CG2 B:THR370 4.9 22.4 1.0

Potassium binding site 2 out of 4 in 7ukg

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Potassium binding site 2 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K602

b:17.7
occ:1.00
 O A:THR370 2.7 22.4 1.0
O D:THR370 2.7 22.3 1.0
O C:THR370 2.7 22.3 1.0
O B:THR370 2.7 22.4 1.0
O D:LEU371 2.8 20.1 1.0
O B:LEU371 2.8 20.3 1.0
O C:LEU371 2.8 20.2 1.0
O A:LEU371 2.9 20.2 1.0
K A:K603 3.3 15.9 1.0
K A:K601 3.4 24.0 1.0
C D:LEU371 3.6 20.1 1.0
C C:LEU371 3.6 20.2 1.0
C B:LEU371 3.6 20.3 1.0
C A:LEU371 3.6 20.2 1.0
C A:THR370 3.8 22.4 1.0
C D:THR370 3.8 22.3 1.0
C C:THR370 3.8 22.3 1.0
C B:THR370 3.8 22.4 1.0
CA D:LEU371 4.0 20.1 1.0
CA C:LEU371 4.0 20.2 1.0
CA B:LEU371 4.0 20.3 1.0
CA A:LEU371 4.0 20.2 1.0
N A:LEU371 4.4 20.2 1.0
N D:LEU371 4.4 20.1 1.0
N C:LEU371 4.4 20.2 1.0
N B:LEU371 4.4 20.3 1.0
N D:GLY372 4.5 18.7 1.0
N C:GLY372 4.5 18.7 1.0
N B:GLY372 4.5 18.6 1.0
N A:GLY372 4.5 18.8 1.0
CA D:GLY372 4.9 18.7 1.0
CA C:GLY372 4.9 18.7 1.0
CA B:GLY372 4.9 18.6 1.0
CA A:GLY372 5.0 18.8 1.0
CA A:THR370 5.0 22.4 1.0

Potassium binding site 3 out of 4 in 7ukg

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Potassium binding site 3 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K603

b:15.9
occ:1.00
 O A:LEU371 2.7 20.2 1.0
O B:LEU371 2.7 20.3 1.0
O D:LEU371 2.7 20.1 1.0
O C:LEU371 2.7 20.2 1.0
O B:GLY372 2.8 18.6 1.0
O D:GLY372 2.8 18.7 1.0
O C:GLY372 2.8 18.7 1.0
O A:GLY372 2.9 18.8 1.0
K A:K602 3.3 17.7 1.0
K B:K601 3.4 18.4 1.0
C B:GLY372 3.5 18.6 1.0
C D:GLY372 3.5 18.7 1.0
C C:GLY372 3.5 18.7 1.0
C A:GLY372 3.5 18.8 1.0
C A:LEU371 3.8 20.2 1.0
C B:LEU371 3.8 20.3 1.0
C C:LEU371 3.8 20.2 1.0
C D:LEU371 3.8 20.1 1.0
CA B:GLY372 3.9 18.6 1.0
CA D:GLY372 3.9 18.7 1.0
CA C:GLY372 3.9 18.7 1.0
CA A:GLY372 3.9 18.8 1.0
N A:GLY372 4.3 18.8 1.0
N B:GLY372 4.3 18.6 1.0
N D:GLY372 4.3 18.7 1.0
N C:GLY372 4.3 18.7 1.0
N B:TYR373 4.4 19.8 1.0
N D:TYR373 4.4 19.6 1.0
N C:TYR373 4.4 19.7 1.0
N A:TYR373 4.4 19.5 1.0
CA B:TYR373 4.8 19.8 1.0
CA C:TYR373 4.8 19.7 1.0
CA D:TYR373 4.8 19.6 1.0
CA A:TYR373 4.8 19.5 1.0

Potassium binding site 4 out of 4 in 7ukg

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Potassium binding site 4 out of 4 in the Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Human KV4.2-KCHIP2-DPP6 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
B:K601

b:18.4
occ:1.00
 O D:TYR373 2.8 19.6 1.0
O B:TYR373 2.8 19.8 1.0
O C:TYR373 2.8 19.7 1.0
O A:TYR373 2.9 19.5 1.0
O A:GLY372 3.0 18.8 1.0
O D:GLY372 3.0 18.7 1.0
O B:GLY372 3.0 18.6 1.0
O C:GLY372 3.0 18.7 1.0
K A:K603 3.4 15.9 1.0
C D:TYR373 3.5 19.6 1.0
C B:TYR373 3.5 19.8 1.0
C C:TYR373 3.5 19.7 1.0
C A:TYR373 3.5 19.5 1.0
CA B:TYR373 4.1 19.8 1.0
CA D:TYR373 4.1 19.6 1.0
CA C:TYR373 4.1 19.7 1.0
CA A:TYR373 4.1 19.5 1.0
C A:GLY372 4.1 18.8 1.0
C D:GLY372 4.1 18.7 1.0
C B:GLY372 4.1 18.6 1.0
C C:GLY372 4.1 18.7 1.0
N D:GLY374 4.3 20.2 1.0
N B:GLY374 4.3 20.3 1.0
N C:GLY374 4.3 20.3 1.0
N A:GLY374 4.3 20.3 1.0
N D:TYR373 4.6 19.6 1.0
N B:TYR373 4.6 19.8 1.0
N A:TYR373 4.6 19.5 1.0
N C:TYR373 4.6 19.7 1.0
CA D:GLY374 4.6 20.2 1.0
CA C:GLY374 4.6 20.3 1.0
CA B:GLY374 4.6 20.3 1.0
CA A:GLY374 4.7 20.3 1.0

Reference:

W.Ye, H.Zhao, Y.Dai, Y.Wang, Y.H.Lo, L.Y.Jan, C.H.Lee. Activation and Closed-State Inactivation Mechanisms of the Human Voltage-Gated K V 4 Channel Complexes. Mol.Cell V. 82 2427 2022.
ISSN: ISSN 1097-2765
PubMed: 35597238
DOI: 10.1016/J.MOLCEL.2022.04.032
Page generated: Mon Aug 12 21:23:22 2024

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