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Potassium in PDB 7uk5: Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region

Potassium Binding Sites:

The binding sites of Potassium atom in the Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region (pdb code 7uk5). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 4 binding sites of Potassium where determined in the Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region, PDB code: 7uk5:
Jump to Potassium binding site number: 1; 2; 3; 4;

Potassium binding site 1 out of 4 in 7uk5

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Potassium binding site 1 out of 4 in the Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K701

b:19.3
occ:1.00
O D:THR370 2.9 16.2 1.0
O A:THR370 2.9 16.6 1.0
O B:THR370 2.9 16.8 1.0
O C:THR370 2.9 16.3 1.0
OG1 D:THR370 3.0 16.2 1.0
OG1 C:THR370 3.0 16.3 1.0
OG1 A:THR370 3.0 16.6 1.0
OG1 B:THR370 3.0 16.8 1.0
K A:K702 3.5 35.5 1.0
CB D:THR370 3.6 16.2 1.0
CB C:THR370 3.6 16.3 1.0
CB A:THR370 3.6 16.6 1.0
CB B:THR370 3.6 16.8 1.0
C D:THR370 4.0 16.2 1.0
C A:THR370 4.0 16.6 1.0
C B:THR370 4.0 16.8 1.0
C C:THR370 4.0 16.3 1.0
CA D:THR370 4.4 16.2 1.0
CA A:THR370 4.4 16.6 1.0
CA B:THR370 4.4 16.8 1.0
CA C:THR370 4.4 16.3 1.0
O B:THR369 4.7 17.7 1.0
O C:THR369 4.7 17.2 1.0
O A:THR369 4.7 17.2 1.0
O D:THR369 4.7 17.1 1.0
CG2 D:THR370 4.8 16.2 1.0
CG2 A:THR370 4.8 16.6 1.0
CG2 B:THR370 4.8 16.8 1.0
CG2 C:THR370 4.8 16.3 1.0

Potassium binding site 2 out of 4 in 7uk5

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Potassium binding site 2 out of 4 in the Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K702

b:35.5
occ:1.00
O A:LEU371 2.6 14.6 1.0
O B:LEU371 2.6 15.0 1.0
O C:LEU371 2.6 15.1 1.0
O D:LEU371 2.6 15.1 1.0
O D:THR370 2.6 16.2 1.0
O A:THR370 2.6 16.6 1.0
O B:THR370 2.6 16.8 1.0
O C:THR370 2.6 16.3 1.0
K A:K703 3.4 35.5 1.0
C C:LEU371 3.4 15.1 1.0
C A:LEU371 3.4 14.6 1.0
C B:LEU371 3.4 15.0 1.0
C D:LEU371 3.4 15.1 1.0
K A:K701 3.5 19.3 1.0
C D:THR370 3.7 16.2 1.0
C A:THR370 3.7 16.6 1.0
C B:THR370 3.7 16.8 1.0
C C:THR370 3.7 16.3 1.0
CA B:LEU371 3.8 15.0 1.0
CA C:LEU371 3.8 15.1 1.0
CA A:LEU371 3.8 14.6 1.0
CA D:LEU371 3.8 15.1 1.0
N D:LEU371 4.2 15.1 1.0
N A:LEU371 4.2 14.6 1.0
N B:LEU371 4.2 15.0 1.0
N C:LEU371 4.2 15.1 1.0
N A:GLY372 4.5 13.7 1.0
N B:GLY372 4.5 13.7 1.0
N C:GLY372 4.5 13.6 1.0
N D:GLY372 4.5 13.5 1.0
CA D:THR370 4.8 16.2 1.0
CA A:THR370 4.8 16.6 1.0
CA B:THR370 4.8 16.8 1.0
CA C:THR370 4.8 16.3 1.0
CA D:GLY372 5.0 13.5 1.0
CA A:GLY372 5.0 13.7 1.0
CA B:GLY372 5.0 13.7 1.0
CA C:GLY372 5.0 13.6 1.0
CB D:THR370 5.0 16.2 1.0
CB C:THR370 5.0 16.3 1.0
CB A:THR370 5.0 16.6 1.0
CB B:THR370 5.0 16.8 1.0

Potassium binding site 3 out of 4 in 7uk5

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Potassium binding site 3 out of 4 in the Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 3 of Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K703

b:35.5
occ:1.00
O A:GLY372 2.5 13.7 1.0
O D:GLY372 2.5 13.5 1.0
O C:GLY372 2.5 13.6 1.0
O B:GLY372 2.5 13.7 1.0
O D:LEU371 2.5 15.1 1.0
O A:LEU371 2.5 14.6 1.0
O B:LEU371 2.5 15.0 1.0
O C:LEU371 2.5 15.1 1.0
C D:GLY372 3.3 13.5 1.0
C A:GLY372 3.3 13.7 1.0
C B:GLY372 3.3 13.7 1.0
C C:GLY372 3.3 13.6 1.0
K A:K702 3.4 35.5 1.0
K A:K704 3.6 35.5 1.0
C D:LEU371 3.6 15.1 1.0
C C:LEU371 3.6 15.1 1.0
C A:LEU371 3.6 14.6 1.0
C B:LEU371 3.6 15.0 1.0
CA D:GLY372 3.7 13.5 1.0
CA A:GLY372 3.7 13.7 1.0
CA B:GLY372 3.7 13.7 1.0
CA C:GLY372 3.7 13.6 1.0
N A:GLY372 4.1 13.7 1.0
N B:GLY372 4.1 13.7 1.0
N C:GLY372 4.1 13.6 1.0
N D:GLY372 4.1 13.5 1.0
N A:TYR373 4.3 16.4 1.0
N B:TYR373 4.3 16.6 1.0
N C:TYR373 4.3 15.9 1.0
N D:TYR373 4.3 15.9 1.0
CA A:TYR373 4.8 16.4 1.0
CA B:TYR373 4.8 16.6 1.0
CA C:TYR373 4.8 15.9 1.0
CA D:TYR373 4.8 15.9 1.0
CA B:LEU371 4.9 15.0 1.0
CA C:LEU371 4.9 15.1 1.0
CA A:LEU371 4.9 14.6 1.0
CA D:LEU371 4.9 15.1 1.0

Potassium binding site 4 out of 4 in 7uk5

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Potassium binding site 4 out of 4 in the Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 4 of Human KV4.2-KCHIP2 Channel Complex in An Open State, Transmembrane Region within 5.0Å range:
probe atom residue distance (Å) B Occ
A:K704

b:35.5
occ:1.00
O C:TYR373 2.8 15.9 1.0
O A:TYR373 2.8 16.4 1.0
O B:TYR373 2.8 16.6 1.0
O D:TYR373 2.8 15.9 1.0
O D:GLY372 2.8 13.5 1.0
O C:GLY372 2.8 13.6 1.0
O B:GLY372 2.8 13.7 1.0
O A:GLY372 2.8 13.7 1.0
C B:TYR373 3.5 16.6 1.0
C C:TYR373 3.5 15.9 1.0
C A:TYR373 3.5 16.4 1.0
C D:TYR373 3.5 15.9 1.0
K A:K703 3.6 35.5 1.0
C D:GLY372 3.9 13.5 1.0
C B:GLY372 4.0 13.7 1.0
C C:GLY372 4.0 13.6 1.0
C A:GLY372 4.0 13.7 1.0
CA A:TYR373 4.0 16.4 1.0
CA B:TYR373 4.0 16.6 1.0
CA C:TYR373 4.0 15.9 1.0
CA D:TYR373 4.0 15.9 1.0
N D:GLY374 4.3 17.4 1.0
N A:GLY374 4.3 17.4 1.0
N B:GLY374 4.3 17.8 1.0
N C:GLY374 4.3 17.1 1.0
N D:TYR373 4.5 15.9 1.0
N A:TYR373 4.5 16.4 1.0
N B:TYR373 4.5 16.6 1.0
N C:TYR373 4.5 15.9 1.0
CA D:GLY374 4.7 17.4 1.0
CA B:GLY374 4.7 17.8 1.0
CA C:GLY374 4.7 17.1 1.0
CA A:GLY374 4.7 17.4 1.0

Reference:

W.Ye, H.Zhao, Y.Dai, Y.Wang, Y.H.Lo, L.Y.Jan, C.H.Lee. Activation and Closed-State Inactivation Mechanisms of the Human Voltage-Gated K V 4 Channel Complexes. Mol.Cell V. 82 2427 2022.
ISSN: ISSN 1097-2765
PubMed: 35597238
DOI: 10.1016/J.MOLCEL.2022.04.032
Page generated: Mon Aug 12 21:20:40 2024

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