Potassium in PDB 7tys: Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation

The binding sites of Potassium atom in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation (pdb code 7tys). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation, PDB code: 7tys:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:K402 b:58.1 occ:1.00 O C:PHE133 2.6 39.4 1.0 O B:PHE133 2.7 39.0 1.0 O D:PHE133 2.7 35.3 1.0 O A:PHE133 2.8 37.5 1.0 C C:PHE133 3.7 32.2 1.0 C D:PHE133 3.8 33.9 1.0 C B:PHE133 3.8 36.5 1.0 C A:PHE133 3.9 31.2 1.0 CA C:GLY134 4.1 41.0 1.0 CA D:GLY134 4.1 45.4 1.0 CA A:GLY134 4.1 29.8 1.0 CA B:GLY134 4.1 36.9 1.0 N C:GLY134 4.4 36.7 1.0 N D:GLY134 4.4 40.2 1.0 N B:GLY134 4.4 36.8 1.0 N A:GLY134 4.5 28.1 1.0 C B:GLY134 4.6 38.2 1.0 O C:GLY132 4.7 32.4 1.0 C A:GLY134 4.7 32.8 1.0 C C:GLY134 4.8 41.6 1.0 C D:GLY134 4.8 46.4 1.0 CA C:PHE133 4.9 24.7 1.0 O D:GLY132 4.9 32.9 1.0 O B:GLY132 4.9 32.3 1.0 O B:GLY134 4.9 46.5 1.0 O A:GLY132 5.0 24.2 1.0 CA D:PHE133 5.0 30.7 1.0

Potassium binding site 2 out of 2 in the Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Cryo-Em Structure of the Pancreatic Atp-Sensitive Potassium Channel Bound to Atp and Repaglinide with KIR6.2-Ctd in the Up Conformation within 5.0Å range: probe atom residue distance (Å) B Occ A:K403 b:44.7 occ:1.00 O B:THR130 2.6 19.9 1.0 O D:THR130 2.6 13.8 1.0 O C:THR130 2.6 28.8 1.0 O A:THR130 2.7 29.7 1.0 O C:ILE131 2.9 21.7 1.0 O B:ILE131 3.1 23.9 1.0 O D:ILE131 3.2 21.3 1.0 O A:ILE131 3.2 19.8 1.0 C C:ILE131 3.6 14.1 1.0 C C:THR130 3.7 13.2 1.0 C B:ILE131 3.7 15.2 1.0 C B:THR130 3.7 15.5 1.0 C D:THR130 3.8 12.0 1.0 C D:ILE131 3.8 17.9 1.0 C A:ILE131 3.8 11.9 1.0 C A:THR130 3.9 19.2 1.0 CA C:ILE131 3.9 9.6 1.0 CA D:ILE131 4.2 16.8 1.0 CA B:ILE131 4.2 11.9 1.0 CA A:ILE131 4.2 2.7 1.0 N C:ILE131 4.3 7.5 1.0 N B:ILE131 4.4 16.8 1.0 N D:ILE131 4.4 11.5 1.0 N A:ILE131 4.6 6.2 1.0 N B:GLY132 4.6 14.2 1.0 N C:GLY132 4.6 19.2 1.0 N D:GLY132 4.6 20.4 1.0 N A:GLY132 4.7 16.5 1.0 CB B:THR130 4.8 20.2 1.0 CA B:THR130 4.8 11.9 1.0 CA C:THR130 4.8 7.6 1.0 CA D:THR130 4.8 13.2 1.0 CB D:THR130 4.9 25.0 1.0 CB C:THR130 4.9 22.2 1.0 CA B:GLY132 4.9 22.6 1.0 OG1 B:THR130 4.9 16.9 1.0 CA A:THR130 5.0 15.9 1.0 CB A:THR130 5.0 19.8 1.0 OG1 D:THR130 5.0 24.9 1.0

M.W.Sung, C.M.Driggers, B.Mostofian, J.D.Russo, B.L.Patton, D.M.Zuckerman, S.L.Shyng. Ligand-Mediated Structural Dynamics of A Mammalian Pancreatic K Atp Channel. J.Mol.Biol. V. 434 67789 2022.
ISSN: ESSN 1089-8638
PubMed: 35964676
DOI: 10.1016/J.JMB.2022.167789