Potassium in PDB 7smp: Cryo-Em Structure of NKCC1 Bu-I

The binding sites of Potassium atom in the Cryo-Em Structure of NKCC1 Bu-I (pdb code 7smp). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Cryo-Em Structure of NKCC1 Bu-I, PDB code: 7smp:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Cryo-Em Structure of NKCC1 Bu-I


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Cryo-Em Structure of NKCC1 Bu-I within 5.0Å range: probe atom residue distance (Å) B Occ B:K1303 b:30.0 occ:1.00 HH B:TYR383 2.0 66.8 1.0 OH B:TYR383 2.6 66.8 1.0 O5 B:82U1302 2.9 69.2 1.0 O B:THR499 2.9 64.7 1.0 HA B:ILE299 2.9 63.4 1.0 O B:PRO496 3.0 68.0 1.0 O B:ALA497 3.1 67.8 1.0 O B:ILE299 3.1 63.4 1.0 O B:ASN298 3.1 64.9 1.0 HA B:ALA497 3.3 67.8 1.0 C B:ILE299 3.7 63.4 1.0 CA B:ILE299 3.7 63.4 1.0 C B:ALA497 3.7 67.8 1.0 HE1 B:TYR383 3.8 66.8 1.0 OG1 B:THR499 3.8 64.7 1.0 CZ B:TYR383 3.8 66.8 1.0 C B:THR499 3.8 64.7 1.0 CA B:ALA497 4.0 67.8 1.0 C17 B:82U1302 4.1 69.2 1.0 HD21 B:ASN298 4.1 64.9 1.0 C B:PRO496 4.1 68.0 1.0 C B:ASN298 4.1 64.9 1.0 H8 B:82U1302 4.1 69.2 1.0 H B:THR499 4.1 64.7 1.0 CE1 B:TYR383 4.2 66.8 1.0 HA3 B:GLY500 4.2 63.3 1.0 HD22 B:ASN298 4.3 64.9 1.0 HG1 B:THR499 4.3 64.7 1.0 N B:THR499 4.3 64.7 1.0 ND2 B:ASN298 4.3 64.9 1.0 N B:ILE299 4.4 63.4 1.0 H2 B:82U1302 4.4 69.2 1.0 HG23 B:ILE299 4.4 63.4 1.0 HG22 B:ILE299 4.5 63.4 1.0 CA B:THR499 4.5 64.7 1.0 HA3 B:GLY301 4.5 68.8 1.0 N B:ALA497 4.5 67.8 1.0 CB B:THR499 4.7 64.7 1.0 N B:GLY500 4.7 63.3 1.0 CG2 B:ILE299 4.8 63.4 1.0 HB3 B:SER614 4.8 66.2 1.0 N B:ALA498 4.8 65.9 1.0 CB B:82U1302 4.8 69.2 1.0 C B:ALA498 4.8 65.9 1.0 N B:TRP300 4.9 66.0 1.0 CB B:ILE299 4.9 63.4 1.0 CG B:82U1302 4.9 69.2 1.0 H3 B:82U1302 4.9 69.2 1.0 O4 B:82U1302 4.9 69.2 1.0 CA B:GLY500 5.0 63.3 1.0 CE2 B:TYR383 5.0 66.8 1.0

Potassium binding site 2 out of 2 in the Cryo-Em Structure of NKCC1 Bu-I


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Cryo-Em Structure of NKCC1 Bu-I within 5.0Å range: probe atom residue distance (Å) B Occ A:K1302 b:30.0 occ:1.00 HH A:TYR383 1.8 107.1 1.0 OH A:TYR383 2.4 107.1 1.0 O A:PRO496 2.9 109.0 1.0 O A:THR499 2.9 100.5 1.0 HA A:ALA497 3.0 107.7 1.0 O5 A:82U1301 3.0 110.9 1.0 O A:ASN298 3.2 100.3 1.0 O A:ALA497 3.3 107.7 1.0 O A:ILE299 3.5 100.9 1.0 HG1 A:THR499 3.6 100.5 1.0 CZ A:TYR383 3.6 107.1 1.0 HA A:ILE299 3.7 100.9 1.0 HE1 A:TYR383 3.7 107.1 1.0 CA A:ALA497 3.7 107.7 1.0 C A:ALA497 3.8 107.7 1.0 C17 A:82U1301 3.8 110.9 1.0 C A:PRO496 3.9 109.0 1.0 OG1 A:THR499 4.0 100.5 1.0 C A:THR499 4.1 100.5 1.0 CE1 A:TYR383 4.1 107.1 1.0 H8 A:82U1301 4.1 110.9 1.0 C A:ILE299 4.2 100.9 1.0 H4 A:82U1301 4.2 110.9 1.0 HA3 A:GLY301 4.2 110.7 1.0 N A:ALA497 4.3 107.7 1.0 C A:ASN298 4.4 100.3 1.0 CA A:ILE299 4.4 100.9 1.0 O4 A:82U1301 4.4 110.9 1.0 HA3 A:GLY500 4.5 96.3 1.0 H3 A:82U1301 4.5 110.9 1.0 H A:THR499 4.6 100.5 1.0 N A:THR499 4.6 100.5 1.0 CG A:82U1301 4.7 110.9 1.0 CB A:82U1301 4.7 110.9 1.0 CE2 A:TYR383 4.8 107.1 1.0 H2 A:82U1301 4.8 110.9 1.0 HB3 A:SER614 4.8 105.6 1.0 CA A:THR499 4.8 100.5 1.0 C8 A:82U1301 4.8 110.9 1.0 HE2 A:TYR383 4.9 107.1 1.0 N A:ALA498 4.9 102.8 1.0 N A:ILE299 4.9 100.9 1.0 CB A:ALA497 5.0 107.7 1.0

M.A.Moseng, C.C.Su, K.Rios, M.Cui, M.Lyu, P.Glaza, P.A.Klenotic, E.Delpire, E.W.Yu. Inhibition Mechanism of NKCC1 Involves the Carboxyl Terminus and Long-Range Conformational Coupling. Sci Adv V. 8 Q0952 2022.
ISSN: ESSN 2375-2548
PubMed: 36306358
DOI: 10.1126/SCIADV.ABQ0952