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Potassium in PDB 7sgi: Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14Enzymatic activity of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
All present enzymatic activity of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14:
3.5.1.48; 3.5.1.62; Protein crystallography data
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14, PDB code: 7sgi
was solved by
C.J.Herbst-Gervasoni,
D.W.Christianson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7sgi:
The structure of Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14 also contains other interesting chemical elements:
Potassium Binding Sites:
The binding sites of Potassium atom in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
(pdb code 7sgi). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14, PDB code: 7sgi: Jump to Potassium binding site number: 1; 2; Potassium binding site 1 out of 2 in 7sgiGo back to Potassium Binding Sites List in 7sgi
Potassium binding site 1 out
of 2 in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
Mono view Stereo pair view
Potassium binding site 2 out of 2 in 7sgiGo back to Potassium Binding Sites List in 7sgi
Potassium binding site 2 out
of 2 in the Crystal Structure of Danio Rerio Histone Deacetylase 10 in Complex with Inhibitor 14
Mono view Stereo pair view
Reference:
R.R.Steimbach,
C.J.Herbst-Gervasoni,
S.Lechner,
T.M.Stewart,
G.Klinke,
J.Ridinger,
M.N.E.Geraldy,
G.Tihanyi,
J.R.Foley,
U.Uhrig,
B.Kuster,
G.Poschet,
R.A.Casero Jr.,
G.Medard,
I.Oehme,
D.W.Christianson,
N.Gunkel,
A.K.Miller.
Aza-Saha Derivatives Are Selective Histone Deacetylase 10 Chemical Probes That Inhibit Polyamine Deacetylation and Phenocopy HDAC10 Knockout. J.Am.Chem.Soc. V. 144 18861 2022.
Page generated: Wed Apr 5 10:17:51 2023
ISSN: ESSN 1520-5126 PubMed: 36200994 DOI: 10.1021/JACS.2C05030 |
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