Potassium in PDB 7s5t: Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0
Potassium Binding Sites:
The binding sites of Potassium atom in the Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0
(pdb code 7s5t). This binding sites where shown within
5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the
Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0, PDB code: 7s5t:
Jump to Potassium binding site number:
1;
2;
Potassium binding site 1 out
of 2 in 7s5t
Go back to
Potassium Binding Sites List in 7s5t
Potassium binding site 1 out
of 2 in the Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 1 of Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K401
b:78.3
occ:1.00
|
O
|
D:GLY132
|
2.9
|
74.0
|
1.0
|
O
|
B:GLY132
|
2.9
|
74.8
|
1.0
|
O
|
A:PHE133
|
2.9
|
75.7
|
1.0
|
O
|
D:PHE133
|
2.9
|
76.0
|
1.0
|
O
|
B:PHE133
|
2.9
|
76.3
|
1.0
|
O
|
C:PHE133
|
2.9
|
76.1
|
1.0
|
O
|
C:GLY132
|
2.9
|
74.5
|
1.0
|
O
|
A:GLY132
|
2.9
|
73.9
|
1.0
|
C
|
D:PHE133
|
3.5
|
76.0
|
1.0
|
C
|
B:PHE133
|
3.5
|
76.3
|
1.0
|
C
|
A:PHE133
|
3.5
|
75.7
|
1.0
|
C
|
C:PHE133
|
3.5
|
76.1
|
1.0
|
C
|
D:GLY132
|
4.0
|
74.0
|
1.0
|
C
|
B:GLY132
|
4.0
|
74.8
|
1.0
|
C
|
C:GLY132
|
4.0
|
74.5
|
1.0
|
C
|
A:GLY132
|
4.0
|
73.9
|
1.0
|
CA
|
D:PHE133
|
4.1
|
76.0
|
1.0
|
CA
|
B:PHE133
|
4.1
|
76.3
|
1.0
|
CA
|
A:PHE133
|
4.1
|
75.7
|
1.0
|
CA
|
C:PHE133
|
4.1
|
76.1
|
1.0
|
N
|
D:GLY134
|
4.3
|
77.6
|
1.0
|
N
|
B:GLY134
|
4.3
|
80.2
|
1.0
|
N
|
C:GLY134
|
4.3
|
78.5
|
1.0
|
N
|
A:GLY134
|
4.3
|
79.2
|
1.0
|
CA
|
B:GLY134
|
4.5
|
80.2
|
1.0
|
CA
|
D:GLY134
|
4.5
|
77.6
|
1.0
|
CA
|
C:GLY134
|
4.5
|
78.5
|
1.0
|
CA
|
A:GLY134
|
4.5
|
79.2
|
1.0
|
N
|
D:PHE133
|
4.6
|
76.0
|
1.0
|
N
|
B:PHE133
|
4.6
|
76.3
|
1.0
|
N
|
C:PHE133
|
4.6
|
76.1
|
1.0
|
N
|
A:PHE133
|
4.6
|
75.7
|
1.0
|
|
Potassium binding site 2 out
of 2 in 7s5t
Go back to
Potassium Binding Sites List in 7s5t
Potassium binding site 2 out
of 2 in the Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0
Mono view
Stereo pair view
|
A full contact list of Potassium with other atoms in the K binding
site number 2 of Human Katp Channel in Open Conformation, Focused on Kir (C166S G334D Double Mutant) and Sur TMD0 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:K402
b:77.3
occ:1.00
|
O
|
D:THR130
|
2.8
|
74.8
|
1.0
|
O
|
B:THR130
|
2.8
|
74.2
|
1.0
|
O
|
C:THR130
|
2.8
|
74.6
|
1.0
|
O
|
A:ILE131
|
2.9
|
71.4
|
1.0
|
O
|
B:ILE131
|
2.9
|
73.1
|
1.0
|
O
|
D:ILE131
|
2.9
|
72.6
|
1.0
|
O
|
A:THR130
|
2.9
|
73.3
|
1.0
|
O
|
C:ILE131
|
2.9
|
72.7
|
1.0
|
C
|
D:ILE131
|
3.6
|
72.6
|
1.0
|
C
|
B:ILE131
|
3.6
|
73.1
|
1.0
|
C
|
A:ILE131
|
3.6
|
71.4
|
1.0
|
C
|
C:ILE131
|
3.6
|
72.7
|
1.0
|
C
|
D:THR130
|
3.8
|
74.8
|
1.0
|
C
|
B:THR130
|
3.8
|
74.2
|
1.0
|
C
|
C:THR130
|
3.8
|
74.6
|
1.0
|
C
|
A:THR130
|
3.8
|
73.3
|
1.0
|
CA
|
D:ILE131
|
4.0
|
72.6
|
1.0
|
CA
|
B:ILE131
|
4.0
|
73.1
|
1.0
|
CA
|
A:ILE131
|
4.0
|
71.4
|
1.0
|
CA
|
C:ILE131
|
4.0
|
72.7
|
1.0
|
N
|
D:ILE131
|
4.3
|
72.6
|
1.0
|
N
|
B:ILE131
|
4.3
|
73.1
|
1.0
|
N
|
C:ILE131
|
4.4
|
72.7
|
1.0
|
N
|
A:ILE131
|
4.4
|
71.4
|
1.0
|
N
|
B:GLY132
|
4.7
|
74.8
|
1.0
|
N
|
D:GLY132
|
4.7
|
74.0
|
1.0
|
N
|
C:GLY132
|
4.7
|
74.5
|
1.0
|
N
|
A:GLY132
|
4.7
|
73.9
|
1.0
|
OG1
|
D:THR130
|
4.9
|
74.8
|
1.0
|
OG1
|
B:THR130
|
4.9
|
74.2
|
1.0
|
OG1
|
C:THR130
|
4.9
|
74.6
|
1.0
|
OG1
|
A:THR130
|
4.9
|
73.3
|
1.0
|
CA
|
D:THR130
|
4.9
|
74.8
|
1.0
|
CA
|
B:THR130
|
4.9
|
74.2
|
1.0
|
CA
|
C:THR130
|
5.0
|
74.6
|
1.0
|
CA
|
A:THR130
|
5.0
|
73.3
|
1.0
|
|
Reference:
C.Zhao,
R.Mackinnon.
Molecular Structure of An Open Human K Atp Channel Proc.Natl.Acad.Sci.Usa V. 118 2021.
ISSN: ESSN 1091-6490
DOI: 10.1073/PNAS.2112267118
Page generated: Fri Dec 17 09:44:34 2021
|