Potassium in PDB 7plk: Crystal Structure Bovine HSC70(AA1-554)E213A/D214A in Complex with Nicotinic-Acid-Derivative

The structure of Crystal Structure Bovine HSC70(AA1-554)E213A/D214A in Complex with Nicotinic-Acid-Derivative, PDB code: 7plk was solved by M.Zehe, C.Grimm, C.Sotriffer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 2.49
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.078, 48.799, 86.476, 90, 99.55, 90
R / Rfree (%)	22.3 / 28.6

The binding sites of Potassium atom in the Crystal Structure Bovine HSC70(AA1-554)E213A/D214A in Complex with Nicotinic-Acid-Derivative (pdb code 7plk). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Crystal Structure Bovine HSC70(AA1-554)E213A/D214A in Complex with Nicotinic-Acid-Derivative, PDB code: 7plk:

Potassium binding site 1 out of 1 in the Crystal Structure Bovine HSC70(AA1-554)E213A/D214A in Complex with Nicotinic-Acid-Derivative


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure Bovine HSC70(AA1-554)E213A/D214A in Complex with Nicotinic-Acid-Derivative within 5.0Å range: probe atom residue distance (Å) B Occ A:K602 b:90.5 occ:1.00 O A:THR145 2.8 25.5 1.0 OE1 A:GLU175 2.9 27.1 1.0 OD1 A:ASP10 2.9 37.5 1.0 OG1 A:THR145 2.9 25.4 1.0 N A:LEU11 3.1 27.2 1.0 O A:LEU11 3.1 34.3 1.0 C A:THR145 3.4 26.2 1.0 C A:LEU11 3.4 33.5 1.0 CD A:GLU175 3.6 26.3 1.0 NZ A:LYS71 3.7 26.8 1.0 CA A:LEU11 3.7 27.3 1.0 C A:ASP10 3.8 28.9 1.0 CG A:GLU175 3.8 23.4 1.0 CA A:ASP10 3.9 27.0 1.0 CB A:THR145 3.9 29.8 1.0 CG A:ASP10 4.0 25.6 1.0 N A:VAL146 4.1 24.4 1.0 N A:GLY12 4.1 31.6 1.0 CA A:THR145 4.1 29.9 1.0 CB A:LEU11 4.1 27.7 1.0 O A:HOH772 4.2 42.8 1.0 CA A:VAL146 4.3 25.0 1.0 CE A:LYS71 4.4 29.1 1.0 N A:THR145 4.4 37.0 1.0 CB A:ASP10 4.5 26.4 1.0 CA A:GLY12 4.6 29.1 1.0 OE2 A:GLU175 4.6 29.1 1.0 O A:ASP10 4.7 27.5 1.0 O A:ILE9 4.8 36.1 1.0 C A:VAL146 5.0 28.7 1.0 O A:HOH708 5.0 43.2 1.0

M.Zehe, C.Schollmayer, J.Kehrein, C.Plank, H.Kovacs, C.Grimm, C.Sotriffer. Combined in-Solution and Crystallographic Fragment Screening on A Two-Domain HSP70 Construct To Be Published.