Potassium in PDB 7odd: Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine

The structure of Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine, PDB code: 7odd was solved by M.Zehe, C.Grimm, C.Sotriffer, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.63 / 1.98
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	66.057, 49.073, 87.271, 90, 99.69, 90
R / Rfree (%)	22.5 / 24.5

The binding sites of Potassium atom in the Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine (pdb code 7odd). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total 2 binding sites of Potassium where determined in the Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine, PDB code: 7odd:
Jump to Potassium binding site number: 1; 2;

Potassium binding site 1 out of 2 in the Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine within 5.0Å range: probe atom residue distance (Å) B Occ A:K606 b:135.9 occ:1.00 OG1 A:THR145 2.6 43.6 1.0 OD1 A:ASP10 2.6 45.5 1.0 OE1 A:GLU175 2.7 40.4 1.0 N A:LEU11 3.0 33.1 1.0 O A:THR145 3.0 42.8 1.0 O A:LEU11 3.2 48.1 1.0 CD A:GLU175 3.3 44.5 1.0 CG A:GLU175 3.5 42.7 1.0 C A:THR145 3.5 44.9 1.0 C A:LEU11 3.5 48.6 1.0 C A:ASP10 3.6 45.3 1.0 CA A:ASP10 3.6 42.4 1.0 O A:HOH710 3.6 34.7 1.0 CG A:ASP10 3.6 37.0 1.0 CB A:THR145 3.7 34.8 1.0 NZ A:LYS71 3.8 39.2 1.0 CA A:LEU11 3.8 43.4 1.0 CB A:ASP10 4.0 35.0 1.0 CA A:THR145 4.0 40.5 1.0 OE2 A:GLU175 4.3 44.3 1.0 N A:VAL146 4.3 46.5 1.0 O07 A:VLS604 4.3 79.7 0.5 N A:GLY12 4.3 48.1 1.0 O07 A:VLS604 4.4 80.2 0.5 N A:THR145 4.5 46.5 1.0 CB A:LEU11 4.5 41.2 1.0 CG1 A:VAL369 4.5 31.2 1.0 C02 A:VLS604 4.6 78.3 0.5 O A:ASP10 4.6 39.5 1.0 C02 A:VLS604 4.6 78.3 0.5 CA A:VAL146 4.6 45.4 1.0 OD2 A:ASP10 4.7 43.4 1.0 O A:ILE9 4.7 43.3 1.0 CA A:GLY12 4.8 47.2 1.0 CE A:LYS71 4.8 40.8 1.0 CB A:GLU175 4.9 49.7 1.0 N A:ASP10 4.9 42.5 1.0 CG2 A:THR145 4.9 39.0 1.0

Potassium binding site 2 out of 2 in the Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 2 of Crystal Structure of Bovine HSC70(AA1-554)E213A/D214A in Complex with Tricine within 5.0Å range: probe atom residue distance (Å) B Occ A:K607 b:132.9 occ:1.00 OD2 A:ASP206 2.9 67.5 1.0 OD2 A:ASP199 3.1 42.8 1.0 OG1 A:THR204 3.2 50.2 1.0 CG A:ASP199 3.2 39.6 1.0 CG A:ASP206 3.3 53.9 1.0 O A:THR204 3.4 47.0 1.0 CB A:ASP206 3.5 47.4 1.0 N A:ASP206 3.5 39.0 1.0 C09 A:VLS604 3.5 77.5 0.5 C09 A:VLS604 3.6 77.5 0.5 O A:ASP199 3.6 41.6 1.0 N08 A:VLS604 3.6 78.0 0.5 N08 A:VLS604 3.6 78.0 0.5 OD1 A:ASP199 3.7 45.1 1.0 CB A:ASP199 3.8 36.5 1.0 C A:THR204 3.8 46.3 1.0 O A:HOH716 3.9 56.9 1.0 CB A:THR204 4.0 38.1 1.0 C A:PHE205 4.0 46.7 1.0 CA A:ASP206 4.1 40.4 1.0 C A:ASP199 4.2 38.7 1.0 CA A:PHE205 4.2 40.6 1.0 N A:PHE205 4.2 39.6 1.0 OD1 A:ASP206 4.2 62.2 1.0 C10 A:VLS604 4.3 78.4 0.5 C10 A:VLS604 4.4 78.4 0.5 N A:GLY201 4.5 36.2 1.0 O12 A:VLS604 4.5 79.0 0.5 O12 A:VLS604 4.5 78.9 0.5 CA A:THR204 4.6 42.2 1.0 CA A:ASP199 4.6 40.3 1.0 O A:PHE205 4.8 47.0 1.0 O A:HOH795 4.9 52.9 1.0 N A:LEU200 4.9 37.0 1.0 C03 A:VLS604 5.0 78.2 0.5 C03 A:VLS604 5.0 78.2 0.5 O05 A:VLS604 5.0 57.2 0.5

M.Zehe, C.Schollmayer, J.Kehrein, C.Plank, H.Kovacs, C.Grimm, C.Sotriffer. Combined in-Solution and Crystallographic Fragment Screening on A Two-Domain HSP70 Construct To Be Published.