Potassium in PDB 7oc1: Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin

All present enzymatic activity of Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin:
2.3.1.179;

The structure of Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin, PDB code: 7oc1 was solved by C.Georgiou, R.Brenk, L.O.Espeland, R.Klein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	68.69 / 1.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	84.024, 137.199, 65.692, 90, 90, 90
R / Rfree (%)	15.7 / 18.8

The binding sites of Potassium atom in the Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin (pdb code 7oc1). This binding sites where shown within 5.0 Angstroms radius around Potassium atom.
In total only one binding site of Potassium was determined in the Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin, PDB code: 7oc1:

Potassium binding site 1 out of 1 in the Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin


Mono view


Stereo pair view

A full contact list of Potassium with other atoms in the K binding site number 1 of Structure of Pseudomonas Aeruginosa Fabf Mutant C164Q in Complex with Platensimycin within 5.0Å range: probe atom residue distance (Å) B Occ A:K507 b:26.4 occ:1.00 OE1 A:GLU350 2.7 7.3 1.0 O A:ASN396 2.7 4.6 1.0 OD1 A:ASN302 2.9 6.5 1.0 OG A:SER395 3.0 7.0 1.0 O A:ASN302 3.0 4.2 1.0 O A:ALA303 3.3 5.8 1.0 CB A:GLU350 3.5 5.3 1.0 N A:ASN396 3.6 4.9 1.0 CD A:GLU350 3.6 6.5 1.0 C A:ALA303 3.7 5.3 1.0 C A:ASN396 3.7 4.8 1.0 C A:ASN302 3.7 5.3 1.0 CG A:ASN302 3.9 6.4 1.0 O A:HOH632 3.9 6.1 1.0 CG A:GLU350 4.0 5.4 1.0 CB A:SER395 4.1 6.0 1.0 N A:HIS304 4.1 4.3 1.0 CB A:ASN302 4.2 5.6 1.0 C A:SER395 4.2 5.2 1.0 CA A:SER395 4.2 5.8 1.0 CA A:ASN396 4.2 5.2 1.0 CA A:HIS304 4.3 4.3 1.0 O A:HOH671 4.4 6.4 1.0 N A:ALA303 4.4 5.3 1.0 CA A:ALA303 4.5 5.3 1.0 OG A:SER397 4.6 5.6 1.0 CA A:ASN302 4.6 5.5 1.0 O A:HOH634 4.6 7.1 1.0 OE2 A:GLU350 4.7 6.2 1.0 N A:SER397 4.8 4.6 1.0 NZ A:LYS336 4.9 5.0 1.0 CA A:GLU350 4.9 4.8 1.0 CB A:ASN396 4.9 5.9 1.0

L.O.Espeland, C.Georgiou, R.Klein, H.Bhukya, B.E.Haug, J.Underhaug, P.S.Mainkar, R.Brenk. An Experimental Toolbox For Structure-Based Hit Discovery For P. Aeruginosa Fabf, A Promising Target For Antibiotics. Chemmedchem 2021.
ISSN: ESSN 1860-7187
PubMed: 34189850
DOI: 10.1002/CMDC.202100302